Clinical trials: sponsored by University of Washington
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington
Substance Abuse, Juvenile Delinquency
The Community Youth Development Study: A Test of Communities That Care
The Community Youth Development Study is an experimental test of the Communities That Care (CTC) prevention planning system. It has been designed to find out if communities that were trained to use the CTC system improved public…
- Conditions
- Substance Abuse, Juvenile Delinquency, Sexual Behavior, Criminal Behavior
- Trial name
- CYDS IV (NCT01088542)
- Testing
- Communities That Care
- Where
- United States
- Volunteers
- 52,323 people, healthy volunteers welcome
- Sponsor
- University of Washington
Bacterial Vaginosis
Effects of a Vaginal Contraceptive Ring on Vaginal Microbiota and Local Immunity
To assess potential benefits associated with both intermittent (use for 3 weeks, remove for 1 week, as defined in the package insert) and continuous (use for 4 weeks, then replace) CVR use among women either with BV or at high…
- Trial name
- NCT02432404
- Testing
- NuvaRing
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cardiac Arrest
Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot
Following resuscitation from out-of-hospital cardiac arrest (OHCA), reperfusion injury can cause cell damage in the heart and brain.
- Trial name
- NCT04265807
- Testing
- Active Remote Ischemic Conditioning
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Washington
Idiopathic Pulmonary Fibrosis
Yoga Effect on Quality of Life Study Among Patients with Idiopathic Pulmonary Fibrosis
This study will evaluate whether regular yoga exercises designed specifically for patients with Idiopathic Pulmonary Fibrosis is associated with any change in quality of life.
- Trial name
- YES-IPF (NCT02848625)
- Testing
- Yoga
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Washington
TBI (Traumatic Brain Injury)
Pediatric Guideline Adherence and Outcomes- Argentina
Pediatric traumatic brain injury (TBI) is the leading killer of children worldwide but effective treatments for TBI are limited.
- Trial name
- PEGASUS (NCT03896789)
- Testing
- PEGASUS Program for Care
- Where
- 16 sites in Argentina, Chile and 1 more
- Volunteers
- 505 people
- Sponsor
- University of Washington
CYP2D6 Polymorphism
Effects of Isotretinoin on CYP2D6 Activity
Specific Aim: To investigate if isotretinoin (13-cis-retinoic acid) administration decreases CYP2D6 activity in adolescent patients.
- Trial name
- NCT03076021
- Testing
- Isotretinoin, dextromethorphan
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Washington
Osteo Arthritis Knee
Pain & Aging: Combined Interventions for Fitness in the Community Study
This clinical trial will determine the added benefit of combining exercise and behavioral health education (versus exercise and aging and health education) to improve physical activity in community-dwelling older adults who have…
- Trial name
- PACIFIC (NCT04099394)
- Testing
- Behavioral Health, Health Education
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- University of Washington
Chronic Pain, Brain Injuries, Traumatic
Telehealth Pain Self-Management for Employed Adults
The E-TIPS trial will evaluate an evidence-based, telehealth pain self-management intervention compared to standard care (a waitlist) for chronic pain in adults with physical disabilities who are employed.
- Conditions
- Chronic Pain, Brain Injuries, Traumatic, Multiple Sclerosis, Spinal Cord Injuries
- Trial name
- E-TIPS (NCT04248725)
- Testing
- E-TIPS
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Washington
Opioid-use Disorder
Mindful Body Awareness With Medication Treatment for Opioid Use Disorder
The national opioid epidemic requires development of real-world evidence-based treatments for opioid use disorder, including adjuncts to Medication for Opioid Use Disorder (MOUD).
- Trial name
- NCT04082637
- Testing
- Mindful Awareness in Body-oriented Therapy
- Where
- 5 sites in United States
- Volunteers
- 303 people
- Sponsor
- University of Washington
Hearing Loss, Hearing Loss, Sensorineural
Evaluation of Artificial Intelligence-Integrated Hearing Aids for Individuals with Hearing Loss
The goal of this clinical trial will be to evaluate the efficacy of artificial intelligence-integrated hearing aids in individuals with hearing loss. The main questions to answer are: 1.
- Trial name
- NCT06792110
- Testing
- Artificial Intelligence Integrated Hearing Aid Use, Phonak Infineo Hearing Aid, Oticon Real Hearing Aid
- Volunteers
- 100 people
- Sponsor
- University of Washington
Depression, Adolescent Behavior
Evaluation of an Asynchronous Remote Communities Approach to Behavioral Activation for Depressed Adolescents
The goal of this clinical trial is to learn if a digital health intervention, called "ActivaTeen," improves depression treatment for teenagers with depression.
- Trial name
- NCT06786247
- Testing
- ActivaTeen, Behavioral Activation
- Volunteers
- 70 people
- Sponsor
- University of Washington
HIV Infections
ARVs to Prevent Breastmilk HIV:Viral and Immune Responses
Identifying new approaches for preventing breastmilk transmission of HIV-1 is an important research priority. To this end, clinical trials are underway to evaluate the efficacy of HAART (zidovudine, lamivudine, nevirapine) during…
- Trial name
- NCT00167674
- Testing
- Combined short-course zidovudine/nevirapine, HAART
- Where
- Kenya
- Volunteers
- 58 people
- Sponsor
- University of Washington
Shigella, Child
Enterics for Global Health (EFGH)
Diarrhea remains a leading cause of death among young children, with the majority of diarrhea deaths occurring in low- and middle-income countries.
- Conditions
- Shigella, Child, Diarrhea
- Trial name
- EFGH (NCT06047821)
- Where
- 33 sites in Bangladesh, Kenya and 5 more
- Volunteers
- 9,800 people
- Sponsor
- University of Washington
HIV Infections, Hiv
HeadStART: Evaluating the Effectiveness of Community ART Delivery for People Newly Diagnosed With HIV
This is a cluster randomized controlled trial at 12 health centers in refugee settlements in Uganda aiming to evaluate effectiveness of expansion of community antiretroviral therapy (ART) delivery to people newly diagnosed with…
- Trial name
- HeadStART (NCT06126913)
- Testing
- Community Antiretroviral Therapy
- Where
- Uganda
- Volunteers
- 2,720 people
- Sponsor
- University of Washington
Juvenile Idiopathic Arthritis
Sleep Shared-Management Intervention for Children With Juvenile Idiopathic Arthritis
Sleep deficiency is a public health concern in children with a chronic illness such as Juvenile Idiopathic Arthritis (JIA) because it is often overlooked in clinical care, attributed to the underlying chronic illness, and…
- Trial name
- SLEEPSMART (NCT04066205)
- Testing
- SLEEPSAMRT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Washington
Pre-Exposure Prophylaxis, HIV Infections
PrEPARE: PrEP in Pregnancy, Accelerating Reach and Efficiency
This study tests strategies for improving PrEP implementation in maternal and child health clinics using a difference-in-difference approach.
- Conditions
- Pre-Exposure Prophylaxis, HIV Infections, Pregnancy Related
- Trial name
- NCT04712994
- Testing
- PrEP Optimization Interventions
- Where
- 8 sites in Kenya
- Volunteers
- 1,958 people, healthy volunteers welcome
- Sponsor
- University of Washington
Recurrent Transformed B-Cell Non-Hodgkin Lymphoma, Refractory Transformed B-Cell Non-Hodgkin Lymphoma
Ibrutinib in Treating Patients With Relapsed or Refractory Transformed Indolent B-cell Non-Hodgkin Lymphoma
This pilot phase II trial studies ibrutinib in treating patients with transformed indolent (a type of cancer that grows slowly) B-cell non-Hodgkin lymphoma that have returned after a period of improvement (relapsed) or do not…
- Trial name
- NCT02207062
- Testing
- Ibrutinib, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Castration-Resistant Prostate Carcinoma, Prostate Adenocarcinoma
Olaparib for the Treatment of Castration Resistant Prostate Adenocarcinoma
This phase II trial investigates the effect of olaparib in treating patients with castration resistant prostate adenocarcinoma. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- NCT04951492
- Testing
- Olaparib
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Washington
Drinking Behavior
Motivating Campus Change Study
The study evaluates the relative merit of a multi-component PFI presented in the traditional simultaneous delivery (i.e., all components at once) versus a sequential format, wherein individual PFI components are delivered one at…
- Trial name
- MC2 (NCT04030325)
- Testing
- Sequential Personalized Feedback Intervention Delivery, Simultaneous Personalized Feedback Intervention Delivery, Text Message Boosters
- Where
- United States
- Volunteers
- 1,012 people, healthy volunteers welcome
- Sponsor
- University of Washington
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