Clinical trials: sponsored by University of Washington
Sudden Death, Out-Of-Hospital Cardiac Arrest
Head-to-pelvis Computed Tomography Evaluation of Sudden Death Survivors
Out-of-hospital arrest can occur from multiple etiologies. In patients without an obvious reason for the sudden-death event, diagnostic evaluation is not clear.
- Trial name
- NCT03111043
- Testing
- Head to pelvis CT scan
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- University of Washington
Autism
Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
The goal of this proposed trial will modify an existing toothbrushing app for teens with autism and compare toothbrushing outcomes with a control app.
- Trial name
- NCT06208722
- Testing
- Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Washington
Smart Eyewear
Smart Eyewear to Automatically Detect Drug Delivery Events
This project is designed as a prospective observational study of medication preparation and delivery using a novel wearable data input device to automate detection of drug delivery events in the anesthesia workspace at University…
- Trial name
- NCT05184660
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Infections
A Cohort for Evaluation of Open-label PrEP Use and PreP Preferences Among African Women
INSIGHT is a Prospective, Observational, open-label cohort study on women in Sub-Saharan Africa on PrEP screening, informed choice, and compliance. There are no specific intervention arms or comparative treatment plans.
- Trial name
- INSIGHT (NCT05746065)
- Testing
- PrEP
- Where
- 20 sites in Eswatini, Kenya and 5 more
- Volunteers
- 3,087 people
- Sponsor
- University of Washington
Dementia
Deprescribing to Reduce Injurious Falls Among Older Adults With Dementia
STOP-FALLS-D is an educational intervention to inform and activate patients, their care partner(s), and their primary care providers to work together to reduce use of central nervous system (CNS) active medications and prevent…
- Trial name
- STOP-FALLS-D (NCT05777772)
- Testing
- STOP Falls D Educational Intervention
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- University of Washington
Closed Transverse Fracture of Shaft of Tibia
Union Rate of Transverse Tibia Fracture
The investigators will compare the three methods of seating a tibial nail - Backslapping or Backslapping with Dynamic Locking or Internal Compression.
- Trial name
- NCT03042533
- Testing
- Conventional Compression, Standard Backslapping, Dynamic Locking with Backslapping
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Washington
Down Syndrome, Trisomy 21
Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down Syndrome
To explore the effects of Partial Body Weight Support (PBWS) within an enriched play environment for infants with Down Syndrome (DS), who are not yet walking, to better understand how PWBS may impact their mobility; exploration…
- Trial name
- NCT05307523
- Testing
- Enriched Play Environment with Partial Body Weight Support Harness, Enriched Play Environment without Partial Body Weight Support Harness
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Washington
Depression
Activating and Connecting Teens (ACT) Study
National data indicate over 650,000 children and adolescents are exposed to physical, sexual, or emotional abuse or physical or emotional neglect each year.
- Trial name
- ACT (NCT03438656)
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Washington
Lower Limb Amputation Below Knee (Injury)
NIH Release/Relock Socket
The goal of the research is to create and evaluate a new technology for management of daily residual limb fluid volume fluctuation.
- Trial name
- NCT04305782
- Testing
- Release/Relock Socket - In Lab, Release/Relock Socket - Out of Lab, Release/Relock Socket & Control
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Spinal Cord Injuries, Spinal Cord Diseases
Comparison of Transcutaneous and Epidural Spinal Stimulation for Improving Function
Incomplete spinal cord injuries (SCI) are the most frequent neurologic category, comprising 66.7% of all SCI cases. People with incomplete SCI may retain some ability to move the legs and therefore the capacity to regain walking.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Central Nervous System Diseases, Nervous System Diseases
- Trial name
- NCT04043715
- Testing
- Transcutaneous spinal stimulation, Epidural spinal stimulation
- Where
- United States
- Sponsor
- University of Washington
Depression, Anxiety
Stay Connected: Testing an Intervention to Combat Coronavirus-related Social Isolation Among Older Adults
This study will use the University of Washington's ALACRITY Center's (UWAC) Discover, Design, Build, \& Test (DDBT) method to develop and test an intervention to address the mental health health needs of older adults in senior…
- Conditions
- Depression, Anxiety, Loneliness
- Trial name
- NCT04966910
- Testing
- Stay Connected, Treatment as usual
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Washington
Alcohol Drinking
The College, Alcohol and Peers Study (CAPS)
The present study will evaluate college students (N=100) from 2- and 4-year colleges/universities between 21-24 years old to assess anxiety, affect, broad social motives (BSM) and peer group influences on drinking and other…
- Trial name
- NCT03890484
- Testing
- Peer Type - New Peer, Peer Type - Close Friends
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Washington
Behavior, Child
Helping Educational Leadership Mobilize Evidence
Many universal, evidence-based prevention practices (EBPPs) have been developed to prevent SEB problems, typically in elementary schools, but progress toward widespread implementation has been slow and few efforts have been made…
- Trial name
- HELM (NCT06340074)
- Testing
- HELM, Implementation Attention Control (IAC)
- Where
- United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of Washington
Post COVID-19 Condition, Post-COVID-19 Syndrome
The COPE Study: Pilot Intervention to Improve Symptom Self-management and Coping in Adults With Post COVID-19
This project is a randomized controlled pilot trial using mixed methods to examine the feasibility, acceptability, and initial effects of a telemedicine group-based intervention designed to improve symptom management and coping…
- Trial name
- NCT05658536
- Testing
- 6-Week Self-Management Group
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Washington
Coronary Artery Disease, Valvular Heart Disease
Sugammadex Titration in Cardiac Surgery Patients
Sugammadex is frequently used to reverse the effects of neuromuscular blocking drugs. The recommended doses are 2 mg/kg or 4 mg/kg depending upon the depth of neuromuscular blockade.
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Aorta Disease, Heart Failure
- Trial name
- NCT05246397
- Testing
- Sugammadex administration
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Breastfeeding, Exclusive, Immunization; Infection
Leading Advancements in the Uptake of Newborn Community Health
The primary objective of the study is to determine the impact of a behavior change intervention that partners Orthodox priests with members of the Health Development Army (HDA) and train them to conduct newborn health outreach to…
- Conditions
- Breastfeeding, Exclusive, Immunization; Infection, Growth; Stunting, Nutritional
- Trial name
- LAUNCH (NCT05111899)
- Testing
- Newborn Health Education
- Where
- Ethiopia
- Volunteers
- 316 people
- Sponsor
- University of Washington
Hypogonadism, Male
Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17
This study will be performed in normal men whose endogenous testosterone production has been temporarily suppressed by the administration of a single dose of 120 mg of the oral GnRH antagonist Relugolix, which is approved for the…
- Trial name
- OralT12 (NCT06312761)
- Testing
- Relugolix 120Mg Tab, Curcumin, Testosterone Undecanoate 237 MG Oral Capsule
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Prevention
Pharmacy Delivery to Expand the Reach of PrEP in Kenya
3 consecutive studies to test a novel model for PrEP initiation and refills in Kenya: pharmacy-based PrEP delivery.
- Trial name
- NCT04558554
- Testing
- pharmacy-based PrEP delivery
- Where
- 2 sites in Kenya
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alzheimer's Disease; Dementia
APOE Genotype and Diet Influences on Alzheimer's Biomarkers
This study involves the collection of cognitive and biomarker responses to HIGH and LOW meals in healthy older adults with and without the APOE E4 genotype.
- Trial name
- NCT03070535
- Testing
- HIGH and LOW meal ingestion
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cystic Fibrosis
Saline Hypertonic in Preschoolers + CT
The purpose of this study is to assess whether inhalation of 7% hypertonic saline (HS) twice daily for 48 weeks reduces structural lung disease as assessed by computed tomography (CT) in comparison with inhalation of 0.9%…
- Trial name
- SHIP-CT (NCT02950883)
- Testing
- Active Treatment Group 7% Hypertonic Saline, Control Group 0.9% Isotonic Saline
- Where
- 25 sites in United States, Australia and 7 more
- Volunteers
- 116 people
- Sponsor
- University of Washington, the Collaborative Health Studies Coordinating Center
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