Clinical trials: sponsored by University of Washington
Urinary Tract Infections (UTI's)
Lactobacillus Probiotic for Prevention of UTI
The purpose of this research is to see whether LACTIN-V (Lactobacillus crispatus CTV-05) is an effective method of preventing recurrent urinary tract infections (UTI's) and to learn the side effects of LACTIN-V.
- Trial name
- NCT03151967
- Testing
- Lactobacillus crispatus CTV-05
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- University of Washington
PTSD
A Lay-Led Intervention for War and Refugee Related Trauma
This study will examine the initial efficacy and feasibility of a program called Islamic Trauma Healing by conducting a small RCT (N = 60) comparing Islamic Trauma Healing in an U.S.
- Trial name
- NCT03502278
- Testing
- Islamic Trauma Healing
- Where
- 2 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Washington
Herpes Simplex Type II
Effect of Tenofovir on Genital Herpes Simplex Virus (HSV) Shedding
The investigators propose a randomized, double blind, placebo-controlled, cross-over trial to evaluate the effect of oral and topical (vaginal gel) tenofovir on genital herpes simplex virus (HSV) shedding among herpes simplex…
- Trial name
- NCT01448616
- Testing
- TDF, Vaginal TFV Gel
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Washington
Alcohol Drinking
Research on Translational Outcomes of Alcohol (Project RETRO)
The primary aim of the current study is to assess the effect of a single dose of carbidopa-levodopa on ad libitum alcohol consumption and alcohol craving in young adults with a history of binge drinking.
- Trial name
- NCT04742348
- Testing
- Carbidopa Levodopa
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Washington
Open tíbia Fracture With Sub-segmental Bone Loss
Calcium Sulfate Spacer in Open Tibia Fractures
Investigators will compare antibiotic impregnated Calcium sulfate versus PMMA versus nothing in these sub-segmental bone defects.
- Trial name
- NCT03042546
- Testing
- Calcium Sulfate, PMMA, No treatment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Washington
Chronic Migraine, Behavioral Treatment
Biofeedback-VR for Treatment of Chronic Migraine
Migraine is a common, debilitating neurologic condition affecting more than 900 million individuals worldwide. Established treatments for migraine include medications, vitamin and herbal supplements, neuromodulation, and…
- Conditions
- Chronic Migraine, Behavioral Treatment, Biofeedback, Virtual Reality
- Trial name
- NCT05720819
- Testing
- Combined biofeedback-virtual reality device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Washington
Prostate Adenocarcinoma
Apalutamide in Treating Patients With Prostate Cancer Who Are in Active Surveillance
This phase II trial studies how well apalutamide works in treating patients with prostate cancer who are in active surveillance. Testosterone can cause the growth of prostate cancer cells.
- Trial name
- NCT02721979
- Testing
- Apalutamide, Laboratory Biomarker Analysis, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Washington
Alzheimer Disease
Triglyceride Effects on Blood Flow in the Human Brain
The 'Western diet' characterized by high fat feeding (HFF) is a risk factor for Alzheimer's disease (AD); however, little is known about mechanisms.
- Trial name
- NCT05218018
- Testing
- Lipid drink
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Washington
Voluntary Medical Male Circumcision
Two-way Texting for VMMC Follow-up in Republic of South Africa
Voluntary medical male circumcision (alternatively abbreviated in the literature as VMMC or MC) is a critical HIV prevention intervention with global support for expansion across sub-Saharan Africa (SSA).
- Trial name
- 2wT_RSA (NCT04327271)
- Testing
- Text-based VMMC follow-up
- Where
- 9 sites in South Africa
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- University of Washington
Chronic Kidney Disease, Sarcopenia
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease
Chronic kidney disease is associated with the loss of skeletal muscle mass and function. This process detrimentally impacts mobility, functional independence, and quality of life.
- Conditions
- Chronic Kidney Disease, Sarcopenia, Frailty
- Trial name
- CoNR (NCT03579693)
- Testing
- CoQ10, Nicotinamide riboside
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Washington
Breast Cancer Screening
CESM ABMR Breast Cancer Screening Trial
This is a single institution, prospective screening trial of women at high risk for developing breast cancer, enriched with women with suspicious lesions on breast MRI which have been recommended for biopsy.
- Trial name
- NCT03517813
- Testing
- Contrast-enhanced Spectral Mammography (CESM)
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of Washington
Major Depression
ESTIA: Computerized Intervention Targeting Cognitive Control Deficits in Depressed Adults
Project:EVO is a video-game based intervention that targets neural networks associated with cognitive control. The same networks have been implicated in poor treatment response in middle and older aged adults suffering from major…
- Trial name
- NCT02891564
- Testing
- Band Together, Control Mobile 3D video game
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy
Performance Evaluation and Research for Older Adults Requiring Major Surgery
The purpose is to identify modifiable factors in older adults associated with functional decline following major non-emergent surgery.
- Trial name
- PERFORM (NCT00487890)
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Washington
Morbid Obesity
Adjustable Gastric Band Survey Study
Our aim is to complete a survey study of patients who have undergone Adjustable Gastric Band (AGB) surgery at the University of Washington Medical Center (UWMC) and expanded to other bariatric surgical sites outside the…
- Trial name
- AGB (NCT01041534)
- Testing
- Survey
- Where
- United States
- Sponsor
- University of Washington
Diverticulitis
DEBUT: Diverticulitis Evaluation of Patient Burden, Utilization, and Trajectory
Half of all Americans over 60 years of age have diverticulitis of the colon. Over the last decade, the use of elective colon resection has increased by more than 50%, and diverticulitis is now the leading reason for elective…
- Trial name
- DEBUT (NCT02776787)
- Where
- 9 sites in United States
- Volunteers
- 418 people
- Sponsor
- University of Washington
HIV-1-infection, Adherence, Medication
Social Media for ART Adherence and Retention in Adolescents and Young Adults: the Vijana-SMART Study
The goal of this study is to investigate whether a virtual peer support group improves ART knowledge, adherence, and mental health in youth living with HIV in Kenya.
- Conditions
- HIV-1-infection, Adherence, Medication, Depression
- Trial name
- NCT05634265
- Testing
- Vijana-SMART
- Where
- Kenya
- Volunteers
- 55 people
- Sponsor
- University of Washington
Post Traumatic Stress Disorder, Problem Drinking
Tools for Health and Resilience Implemented After Violence Exposure (Project THRIVE)
Sexual assault victimization is a common and particularly harmful form of trauma that is associated with increased risk for high-risk drinking and other conditions of public health concern, such as PTSD.
- Trial name
- NCT03703258
- Testing
- App-based intervention
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Washington
Cystic Fibrosis
A Pharmacokinetic and Safety Study of IV Gallium Nitrate (Ganite) in Cystic Fibrosis Patients
The purpose of this research study is to test the pharmacokinetics, safety, and tolerability of an intravenous infusion of a drug called Ganite (gallium nitrate) in patients with cystic fibrosis.
- Trial name
- NCT01093521
- Testing
- 100 mg/m2 dose, 200 mg/m2 dose
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
HIV/AIDS, Hepatitis C
Study of HIV, HCV, APS and Phylogenetics for PWID
This study will determine whether assisted partner notification services (APS) can identify and link to care, the sexual and needle-sharing partners of HIV-infected and HIV/hepatitis C (HCV) co-infected persons who inject drugs…
- Trial name
- SHARP (NCT03447210)
- Testing
- Assisted Partner Services
- Where
- 3 sites in Kenya
- Volunteers
- 4,301 people
- Sponsor
- University of Washington
Chronic Pain
Self-Management Interventions for Chronic Pain Relief With Cancer Survivors
Cancer survivors who suffer from chronic pain would benefit from a low-cost, self-management intervention they can use at home. This study will evaluate the efficacy of a recorded hypnosis intervention in reducing chronic pain…
- Trial name
- NCT03867760
- Testing
- Recorded Hypnosis Intervention, Recorded Relaxation Intervention
- Where
- 2 sites in United States
- Volunteers
- 109 people
- Sponsor
- University of Washington
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