Clinical trials: sponsored by University of Washington
Pain, Acute
Water-friendly Virtual Reality and Brief Thermal Pain
Using immersive virtual reality as a form of pain distraction during a brief "painful but tolerable" temperature.
- Trial name
- NCT04245475
- Testing
- Virtual Reality psychological pain reduction
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Washington
Male Infertility, Azoospermia
RA-4: 13-cis Retinoic Acid for Treatment of Men With Azoospermia
Men with infertility and normal hormone levels have few options for fertility treatment. Previous research suggests that men with infertility may have low levels of the active form of Vitamin A, called retinoic acid, in their…
- Trial name
- NCT03323801
- Testing
- 13-cis retinoic acid
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
HIV-1-infection
The Partners Scale-Up Project
An implementation project to scale-up delivery of antiretroviral-based HIV-1 prevention methods to Kenyan HIV-1 serodiscordant couples in HIV-1 care centers.
- Trial name
- NCT03052010
- Testing
- Integrated PrEP as a bridge to ART HIV-1 prevention strategy, PrEP, ART
- Where
- 2 sites in Kenya
- Volunteers
- 4,898 people, healthy volunteers welcome
- Sponsor
- University of Washington
Parent-child Interaction
Beginning Relationships in a Native Community
The purpose of this study is to to conduct a randomized controlled trial comparing an intervention group and a control/wait list group to evaluate the feasibility of the Promoting First Relationships method in an American Indian…
- Trial name
- P20-RP3 (NCT02091804)
- Testing
- Immediate Group, Wait-List group
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Washington
Opioid-Related Disorders
Trial of Adherence App for Buprenorphine Treatment (TAAB) Study
The purpose of this study is to pilot test a smartphone application that allows video-based directly observed therapy for participants receiving buprenorphine treatment for opioid use disorder in office-based settings.
- Trial name
- NCT03779997
- Testing
- Video-based DOT Application
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- University of Washington
COPD, Depression
Cognitive Behavioral Therapy for COPD
The purpose of this study in patients with advanced COPD and depression is twofold: 1. Determine the feasibility and acceptability of a 6-session e-counseling intervention 2.
- Trial name
- CLIMB (NCT01694628)
- Testing
- CLIMB (COPD Lifestyle, Mood, and Behavior)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Washington
Drinking; Excess, Habit (Continual), Identity, Social
Evaluating Change in Drinking Identity as a Mechanism for Reducing Hazardous Drinking - Study 2
The purpose of the proposed research is to evaluate whether changes in drinking identity (DI; how much one associates one's self with drinking) can reduce hazardous drinking (HD; heavy alcohol use and negative alcohol-related…
- Trial name
- NCT03889873
- Testing
- Narrative Writing
- Where
- United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- University of Washington
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma
Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
This partially randomized phase I/II trial studies the side effects and how well sirolimus works when given together with docetaxel and carboplatin in treating patients with castration-resistant prostate cancer that has spread to…
- Conditions
- Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IV Prostate Cancer AJCC v7, Metastatic Malignant Neoplasm in the Bone
- Trial name
- NCT02565901
- Testing
- Carboplatin, Docetaxel, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Washington
Estrogen Receptor Negative, HER2/Neu Negative
Collecting, Analyzing, and Storing Samples From Patients With Metastatic, Triple Negative Breast Cancer Receiving Anti-cancer Therapy
This pilot research trial studies collecting, analyzing, and storing samples from patients with triple negative breast cancer (breast cancer cells that do not have estrogen receptors, progesterone receptors, or large amounts of…
- Conditions
- Estrogen Receptor Negative, HER2/Neu Negative, Progesterone Receptor Negative, Stage IV Breast Cancer AJCC v6 and v7
- Trial name
- ITOMIC (NCT01957514)
- Testing
- Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Quality-of-Life Assessment
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Washington
Sporadic Amyotrophic Lateral Sclerosis
Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (SALS)
The purpose of this research is to find out if mexiletine is safe and effective in people with Amyotrophic Lateral Sclerosis (ALS).
- Trial name
- MX-ALS-001 (NCT01849770)
- Testing
- Mexiletine
- Where
- 10 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Washington
Post-Traumatic Headache, Traumatic Brain Injury
Acupuncture for Headache Post-Traumatic Brain Injury: A Feasibility Study
This study evaluates and addresses challenges to implementing an acupuncture intervention for adults who have headaches after sustaining a moderate traumatic brain injury.
- Trial name
- NCT04216173
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Washington
HIV Pre-exposure Prophylaxis During Breastfeeding
PrEP in Breastfeeding Study
The purpose of this study is to quantify the magnitude and extent of infant exposure to daily emtricitabine (FTC) /tenofovir disoproxil fumarate (TDF) via maternal breastmilk when taken pre-exposure prophylaxis (PrEP) by…
- Trial name
- NCT02776748
- Testing
- FTC/TDF PrEP
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 50 people
- Sponsor
- University of Washington
Mental Health Issue, Adoption of Measurement-Based Care (MBC)
Brief Online Training (BOLT) for Routine Outcome Monitoring
The goal of this project is to improve school-based services by developing and testing an online training and consultation system to facilitate the use of measurement-based care (also known and referenced in original grant as…
- Trial name
- NCT05041517
- Testing
- BOLT + PTC
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Washington
Analgesia
Assessment of the Effect of Age on Duration of Analgesia From Single-shot Femoral Nerve Blocks
Cohort study to examine the effect of age on duration of analgesia in patients receiving single-shot femoral nerve block prior to surgery, by postoperative phone follow-up questionnaire.
- Trial name
- NCT04495413
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Parent-child Interaction
A Primary Prevention Trial to Strengthen Child Attachment in a Native Community
The purpose of this study is to to conduct a randomized controlled trial comparing an intervention group and a control group to evaluate the feasibility of the Promoting First Relationships method in an American Indian community…
- Trial name
- FPT PFR (NCT02139332)
- Testing
- PFR Group, Resource & Referral Group
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Washington
Chronic Kidney Disease
Clearance of 25-hydroxyvitamin D in Chronic Kidney Disease
The goal of this study is to better understand vitamin D catabolism and how it is affected by CKD and race.
- Trial name
- CLEAR (NCT02937350)
- Testing
- D6-25-hydroxyvitamin D3
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Washington
Cystic Fibrosis, Patient Engagement
Cystic Fibrosis Reproductive and Sexual Health Collaborative: Building Online Research Partnerships
This is a Patient-Centered Outcomes Research Institute engagement effort aimed at training researchers/providers and patients to work in research teams together online throughout the research process (including: development…
- Trial name
- NCT04999865
- Testing
- 4-part educational program to build patient-engagement methodology capacity
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Schizophrenia, Schizoaffective Disorder
Evaluation of mHealth for Serious Mental Illness
This study is a waitlist control trial evaluating the acceptability and preliminary efficacy of a smartphone application with people with mental illness.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Major Depressive Disorder, Bipolar Disorder
- Trial name
- NCT04068467
- Testing
- Smartphone App, Waitlist Control
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- University of Washington
Ann Arbor Stage I Mantle Cell Lymphoma, Ann Arbor Stage II Mantle Cell Lymphoma
Enzalutamide in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma
This pilot clinical trial studies enzalutamide in treating patients with mantle cell lymphoma that has returned after a period of improvement (relapsed) or has not responded to previous treatment (refractory).
- Conditions
- Ann Arbor Stage I Mantle Cell Lymphoma, Ann Arbor Stage II Mantle Cell Lymphoma, Ann Arbor Stage III Mantle Cell Lymphoma, Ann Arbor Stage IV Mantle Cell Lymphoma
- Trial name
- NCT02489123
- Testing
- Enzalutamide, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Washington
Influenza, Respiratory Viral Infection
Pilot of Cohort of Households for Influenza Monitoring and Evaluation in Seattle
This study will evaluate a home-based approach to influenza infection control, using prepositioned home-based influenza self-test kits, telemedicine services, and rapid delivery of Xofluza (Baloxavir marboxil) for administration…
- Trial name
- pCHIMES (NCT04141930)
- Testing
- Baloxavir Marboxil
- Where
- United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- University of Washington
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