Clinical trials: sponsored by University of Washington
Sleep Disturbance, Asthma
Sleep Intervention for Kids and Parents: A Self-Management Pilot Study
Behavioral intervention for 6-11 year children with persistent asthma and sleep disturbance and a parent with sleep disturbance.
- Trial name
- SKIP (NCT03144531)
- Testing
- Sleep Intervention for Kids and Parents (SKIP)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Washington
Male Infertility, Klinefelter's Syndrome
RA-2 13-cis Retinoic Acid (Isotretinoin)
Men with infertility and normal hormone levels have few options for fertility treatment. Previous research work has suggested that men with infertility may have low levels of the active form of Vitamin A, called retinoic acid, in…
- Conditions
- Male Infertility, Klinefelter's Syndrome, Y-chromosome Microdeletions
- Trial name
- RA-2 (NCT02061384)
- Testing
- 13-cis retinoic acid, Calcitriol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Metastatic Breast Cancer With BRCA 1 or BRCA 2 Genetic Mutation, Triple-Negative Breast Cancer
Expanded Access With ABT-888 (Veliparib) to Treat Metastatic Breast Cancer
This is an expanded access protocol to allow continued maintenance therapy with ABT-888 (veliparib) for three patients with metastatic triple negative breast cancer who are currently receiving the investigational product in…
- Trial name
- NCT02985658
- Testing
- Veliparib, Cisplatin, Vinorelbine
- Where
- United States
- Sponsor
- University of Washington
Opioid-use Disorder
Treatment Navigation for Opioid Use Disorder
The investigators will conduct a pilot randomized controlled trial (RCT) study of 100 people with a history of opioid use disorder releasing to WA Department of Corrections (DOC) community corrections supervision in King County.
- Trial name
- NCT03398265
- Testing
- Treatment Navigation (Intervention), Control
- Where
- 5 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Washington
Recurrent Non-Small Cell Lung Carcinoma, Stage IV Non-Small Cell Lung Cancer
Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Previously Treated Advanced Non-small Cell Lung Cancer
This research study examines the use of Abraxane (paclitaxel albumin-stabilized nanoparticle formulation) in patients with lung cancer. Abraxane is a chemotherapy approved to treat patients with breast cancer.
- Trial name
- NCT01620190
- Testing
- Laboratory Biomarker Analysis, Paclitaxel Albumin-Stabilized Nanoparticle Formulation
- Where
- 12 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Washington
Breast Cancer Stage I, Breast Cancer Stage III
Occupational Therapist-Led Work Intervention in Facilitating Work Maintenance or Re-entry to the Workforce in Patients With Stage I to III Breast Cancer Undergoing Chemotherapy
This trial studies how well occupational therapy (occupational therapist-led work intervention) works in facilitating work maintenance or re-entry to the workforce for stages I to III breast cancer patients who will be undergoing…
- Conditions
- Breast Cancer Stage I, Breast Cancer Stage III, Breast Cancer Stage II, Breast Cancer Stage IIA
- Trial name
- NCT03723863
- Testing
- Occupational Therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Washington
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
The overarching goal of this UH2-UH3 proposal is to work with the NIH Health Care Systems Research Collaboratory to develop and implement a large scale, cluster randomized pragmatic clinical trial demonstration project that…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02655354)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management
- Where
- 24 sites in United States
- Volunteers
- 635 people
- Sponsor
- University of Washington
Estrogen Receptor Positive, Recurrent Breast Carcinoma
F-18 FES PET/CT in Measuring Hormone Expression in Patients With Primary, Recurrent, or Metastatic Breast Cancer Undergoing Endocrine-Targeted Therapy
This clinical trial studies use of F-18 16 alpha-fluoroestradiol ([F-18] FES) positron emission tomography (PET)/computed tomography (CT) in measuring tumor hormone receptor expression in patients undergoing endocrine-targeted…
- Conditions
- Estrogen Receptor Positive, Recurrent Breast Carcinoma, Stage IV Breast Cancer AJCC v6 and v7
- Trial name
- NCT02149173
- Testing
- Computed Tomography, F-18 16 Alpha-Fluoroestradiol, Fludeoxyglucose F-18
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Washington
Major Depression
Comparing Engage to PST for Late Life Depression
This is a non-inferiority trial of Engage, a new intervention for late-life depression, and problem solving therapy (PST). Patient participants will be randomized to either Engage or PST and receive 9 weeks of either…
- Trial name
- Engage (NCT02086201)
- Testing
- Problem Solving Therapy, Engage
- Where
- 2 sites in United States
- Volunteers
- 262 people
- Sponsor
- University of Washington
HIV
Financial Incentives to Increase Pediatric HIV Testing
The purpose of this study is to determine whether giving small financial incentives will motivate parents to test their children for HIV.
- Trial name
- FIT (NCT03049917)
- Testing
- Financial incentive
- Where
- Kenya
- Volunteers
- 452 people
- Sponsor
- University of Washington
Acute Myeloid Leukemia
Feasibility of Partners in Care Program for Caregivers of Patients With Acute Myeloid Leukemia
This trial studies the feasibility of delivering the Partners in Care Program to caregivers of patients with acute myeloid leukemia.
- Trial name
- NCT03806192
- Testing
- Telephone-Based Intervention, Behavioral, Psychological or Informational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Washington
Posttraumatic Stress Disorders
Veterans Nature Therapy (Vet Hike)
This pilot study evaluates the feasibility of conducting a study to evaluate the impact of nature exposure/hiking in groups on symptoms of posttraumatic stress disorder in Veterans.
- Trial name
- NCT03997344
- Testing
- Group nature hikes, Group urban hikes
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Washington
Asthma in Children
Home Air in Agriculture: Pediatric Intervention Trial
This study seeks to reduce exposure to asthmagens in the homes of a community of Latino children residing in an area of intense agricultural production in Eastern Washington by testing the effectiveness of an intervention (high…
- Trial name
- HAPI (NCT04919915)
- Testing
- HEPA air cleaner
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Washington
HIV/AIDS
Impact of Physical Activity and Diet on Symptom Experience in People Living With HIV
We will conduct a four-year, observational study of 850 participants to measure physical activity and diet, once a year for three years.
- Trial name
- PROSPER-HIV (NCT03790501)
- Testing
- No intervention
- Where
- 4 sites in United States
- Volunteers
- 850 people
- Sponsor
- University of Washington
Hypertension, Dietary Modification
Hypertension Prevention Program, Implementation and Scale up- a Hybrid Effectiveness Implementation Study
This is an effectiveness-implementation study to assess the effectiveness of a peer-led multi-component lifestyle program that will aim to lower BP among pre-hypertensive individuals in Nepal.
- Conditions
- Hypertension, Dietary Modification, Health Behavior
- Trial name
- NCT04899648
- Testing
- Behavioral Intervention Group
- Volunteers
- 500 people
- Sponsor
- University of Washington
Syphilis
Lumbar Puncture and Syphilis Outcome
Treponema pallidum, the bacterium that causes syphilis, invades the central nervous system in about 40% of patients with syphilis. This happens early after infection.
- Trial name
- NCT02031146
- Testing
- Lumbar puncture
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- University of Washington
Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma
Abiraterone Acetate in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
This phase II trial studies how well abiraterone acetate works in treating patients with hormone-resistant prostate cancer that has spread from the primary site (place where it started) to other places in the body (metastatic).
- Conditions
- Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Adenocarcinoma
- Trial name
- NCT01503229
- Testing
- Abiraterone Acetate, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Washington
Mild to Heavy Alcohol Consumption
Cognitive, Behavioral and Aging Effects of Pain Medication in Alcohol Users
The purpose of this study is to examine the relationship between heavy alcohol use, pain, and response to pain medication in older adults.
- Trial name
- CAAP (NCT02945293)
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Washington
Epinephrine Causing Adverse Effects in Therapeutic Use
Cardiovascular Effects of Racemic Epinephrine Pellets
The primary aim of this study was to determine if topical racemic epinephrine pellets affect heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) or mean arterial pressure (MAP) in children receiving…
- Trial name
- NCT04688346
- Testing
- HemeRX epinephrine pellets
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Washington
Knee Osteoarthritis
Study for Rural Innovations in the Delivery of Exercise
: Falls are the primary cause of injury and a leading cause of disability and mortality among older adults. Risk factors for falling are common among older adults with knee osteoarthritis (OA) - a highly prevalent condition.
- Trial name
- STRIDE (NCT04881864)
- Testing
- Tele-Enhance Fitness
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Washington
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