Clinical trials: sponsored by University of Washington
Composite Lymphoma, Grade 3b Follicular Lymphoma
Pembrolizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Diffuse Large B-cell Lymphoma or Grade 3b Follicular Lymphoma
This pilot phase I trial studies the side effects of pembrolizumab and combination chemotherapy in treating patients with previously untreated diffuse large B-cell lymphoma or grade 3b follicular lymphoma.
- Conditions
- Composite Lymphoma, Grade 3b Follicular Lymphoma, Stage I Diffuse Large B-Cell Lymphoma, Stage I Follicular Lymphoma
- Trial name
- NCT02541565
- Testing
- Cyclophosphamide, Doxorubicin Hydrochloride, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Washington
Aneurysm, Cerebral Aneurysm
Doppler Flow Wires in Cerebral Angiography
The purpose of this study is to use a wire with a Doppler tip to measure blood flow in vessels in the brain and determine hemodynamic factors associated with treatment success or failure.
- Trial name
- NCT03145701
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Washington
Prostate Adenocarcinoma Without Neuroendocrine Differentiation, Stage I Prostate Cancer AJCC v8
Olaparib Before Surgery in Treating Participants With Localized Prostate Cancer
This phase II trial studies how well olaparib works in treating participants with prostate cancer that has not spread to other parts of the body (localized).
- Conditions
- Prostate Adenocarcinoma Without Neuroendocrine Differentiation, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage IIA Prostate Cancer AJCC v8
- Trial name
- NCT03570476
- Testing
- Olaparib, Radical Prostatectomy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Washington
Cervical Cancer
Randomized Trial of In-Home Cervical Cancer Screening in Underscreened Women
The purpose of this trial is to determine whether mailing in-home human papillomavirus (HPV) screening kits is effective in increasing uptake of cervical cancer screening and early detection and treatment of cervical neoplasia in…
- Trial name
- NCT02005510
- Testing
- Mailed in-home high-risk HPV testing kit, Usual care
- Where
- United States
- Volunteers
- 19,851 people
- Sponsor
- University of Washington
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
The goal of this pilot study is to develop and implement a larger scale, multi-site stepped collaborative care trial that targets injured patients with presentations of posttraumatic stress disorder (PTSD) and related…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02335125)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Psychotropic Drugs
- Volunteers
- 40 people
- Sponsor
- University of Washington
Amputation
Microprocessor Knees in Early Rehabilitation
High-quality, empirical evidence to guide prosthetic rehabilitation following amputation ensures that Service members, Veterans, and civilians who experience limb loss have the potential to receive the highest quality care…
- Trial name
- NCT03433300
- Testing
- Ottobock Kenevo/C-Leg, Ottobock 3R60/3R62
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Washington
B Acute Lymphoblastic Leukemia, Minimal Residual Disease
Pembrolizumab in Treating Minimal Residual Disease in Patients With Acute Lymphoblastic Leukemia
This phase II trial studies how well pembrolizumab works in treating small amounts of cancer cells that remain after attempts to remove the cancer has been made in patients with acute lymphoblastic leukemia.
- Conditions
- B Acute Lymphoblastic Leukemia, Minimal Residual Disease, Recurrent Acute Lymphoblastic Leukemia, T Acute Lymphoblastic Leukemia
- Trial name
- NCT02767934
- Testing
- Laboratory Biomarker Analysis, Pembrolizumab
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Washington
Pharyngeal Gonococcal Infection
Gent for Pharyngeal Gonorrhea (GC)
The Centers for Disease Control and Prevention has identified antimicrobial-resistant (AMR) Neisseria gonorrhoeae (NG) as one of the nation's top three urgent AMR threats.
- Trial name
- NCT03632109
- Testing
- gentamicin 360mg IM
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Washington
Atypical Squamous Cell of Undetermined Significance, Cervical Carcinoma
Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening
This randomized clinical trial studies home-based HPV or clinic-based Pap screening for cervical cancer. It is not yet known whether home-based screening is more effective, cost-effective, and/or acceptable than clinic-based…
- Conditions
- Atypical Squamous Cell of Undetermined Significance, Cervical Carcinoma, Cervical Intraepithelial Neoplasia Grade 2/3, Health Status Unknown
- Trial name
- NCT01550783
- Testing
- Cervical Papanicolaou Test, Cytology Specimen Collection Procedure, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 1,335 people, healthy volunteers welcome
- Sponsor
- University of Washington
Recurrent Breast Carcinoma, Stage IV Breast Cancer
Eribulin Mesylate in Treating Patients With Previously Treated Metastatic Breast Cancer
This phase II trial studies how well eribulin mesylate works in treating patients with previously treated breast cancer that has spread to other places in the body.
- Trial name
- NCT01908101
- Testing
- Eribulin Mesylate, Laboratory Biomarker Analysis
- Where
- 12 sites in United States
- Volunteers
- 86 people
- Sponsor
- University of Washington
ICD
Nursing Interventions Following Sudden Cardiac Arrest
Determine the benefits of implantable cardioverter defibrillator (ICD) patients participating in a structured, 8-week educational telephone intervention delivered by expert cardiovascular nurses post-ICD.
- Trial name
- NCT04462887
- Testing
- Nursing intervention program
- Volunteers
- 168 people
- Sponsor
- University of Washington
Suicidal Ideation Active, Suicidal and Self-injurious Behavior
Military Continuity Project
The investigators propose to utilize text messaging to create and investigate the efficacy of a Continuing Contacts via Text (CCVT) intervention that extends the continuity of care for Service Members with a recent suicide…
- Trial name
- MCP (NCT01829620)
- Testing
- TAU, CCVT+TAU
- Where
- 3 sites in United States
- Volunteers
- 658 people
- Sponsor
- University of Washington
Pharmacogenetics
Naproxen Pharmacogenetic Study (Project 1, Aim 2)
This is a mechanism-based study in healthy adults to determine the effect of the CYP2C9 M1L gene polymorphism on the functional activity of the encoded CYP2C9 enzyme towards the probe substrate naproxen.
- Trial name
- NCT04449471
- Testing
- Naproxen tablet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pain
Virtual Reality Water Friendly Wound Care
Using virtual reality as a form of distraction during a painful burn wound care procedure in addition to pain medication.
- Trial name
- H2OWC (NCT02646787)
- Testing
- Active Virtual Reality, Passive Virtual Reality
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Washington
Stress
Interoceptive Engagement
The proposed project is the first pilot test to examine interoceptive function as a mechanistic biomarker underlying Mindful Awareness in Body-oriented Therapy (MABT).
- Trial name
- NCT03583060
- Testing
- Mindful Awareness in body-oriented therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Washington
Educational Problems
The Flipped Classroom Approach in Ophthalmology Residency
This study aims to evaluate the flipped classroom approach compared to the traditional classroom approach in teaching horizontal strabismus in ophthalmology residency didactics.
- Trial name
- NCT04381676
- Testing
- Flipped Classroom Approach
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Washington
Oral Lichen Planus, Oral Lichenoid Mucositis
Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions.
Oral lichen planus (OLP) is a common chronic autoimmune disease associated with cell-mediated immunological dysfunction. Symptomatic OLP is painful and complete healing is rare.
- Conditions
- Oral Lichen Planus, Oral Lichenoid Mucositis, Oral Lichenoid Reaction
- Trial name
- NCT03509675
- Testing
- Ibuprofen suspension 5mg/100ml
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Washington
Multiple Sclerosis
Study of Exercise on Impact of Cognitive Functioning in Multiple Sclerosis Patients
Cognitive impairment affects roughly 50% of people with multiple sclerosis (MS). There are currently no satisfactory medical treatments for cognitive impairments related to MS and alternative forms of treatment are needed.
- Trial name
- NCT02106052
- Testing
- Aerobic exercise, Stretching and toning exercise
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Washington
Stage IIA Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma
Pazopanib Hydrochloride Followed by Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma
This randomized pilot clinical trial studies pazopanib hydrochloride followed by chemotherapy and surgery in treating patients with soft tissue sarcoma.
- Conditions
- Stage IIA Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma
- Trial name
- NCT01446809
- Testing
- Doxorubicin Hydrochloride, External Beam Radiation Therapy, Ifosfamide
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Washington
Wounds, Gunshot
Helping Individuals With Firearm Injuries
The investigators will conduct a cluster randomized trial of an intervention program that combines a hospital-based intervention, structured outreach program, and multi-agency attention.
- Trial name
- HIFI (NCT02630225)
- Testing
- Critical Time Intervention, Treatment as Usual, Motivational Interviewing
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- University of Washington
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.