Clinical trials: sponsored by University of Zurich
Copd, Chronic Respiratory Disease
Quality-of-Life Management for COPD Patients
The investigators aim to investigate the effects of a telemonitoring and chatbot-based application of "Living well with COPD" (CAir) on health-related quality-of-life in patients with COPD.
- Trial name
- CAir (NCT04373070)
- Testing
- CAir
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University of Zurich
Palliative Care
Dignity Therapy+: A Brief Psychological and Existential Intervention for Dying Patients and Their Families.
Background: There has been significant progress in symptom management, pain relief and improvement of quality of life in patients nearing death by implementing palliative care programs.
- Trial name
- DT-plus (NCT02646527)
- Testing
- Dignity Therapy
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Altitude Hypoxia
Effect of Acetazolamide on Right Heart Function During Exercise in Lowlanders Older Than 40 Years at Altitude
Randomized, placebo controlled trial evaluating efficacy of acetazolamide on right heart function during exercise in lowlanders older than 40 years travelling from 760 m to 3'100 m.
- Trial name
- NCT03537924
- Testing
- ACETAZOLAMIDE oral capsule
- Where
- Kyrgyzstan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pulmonary Hypertension Outcome Assessment
Zürich Pulmonary Hypertension Outcome Assessment Cohort
PH is a serious disease with a dismal prognosis and impaired quality of life when left untreated. Reliable patient centered and prognostically relevant outcome measures are highly warranted in the field of PH.
- Trial name
- ZHPHCohort (NCT02249806)
- Testing
- PH target therapy according to physician
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Interstitial Lung Disease
Effect of Short-term Oxygen During CPET in ILD
In a randomized, sham-controlled crossover trial the investigators will test whether supplemental oxygen given during cardiopulmonary exercise testing will improve exercise performance and physiological parameters in patients…
- Trial name
- NCT04897048
- Testing
- Incremental exercise test (IET), Constant work rate exercise test (CWRET)
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University of Zurich
Pulmonary Hypertension
Effect of Normobaric Hypoxia and Hyperoxia in Patients With Pulmonary Hypertension
Pulmonary Hypertension (PH) is a severe disease with a bad prognosis. However, thanks to extensive research in this field, there are more and better treatment options that allow patients to participate in recreational activities…
- Trial name
- NCT03195959
- Testing
- Hypoxia and Hyperoxia
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- University of Zurich
Right Heart Function, Chronic Obstructive Pulmonary Disease
Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude
The purpose of this randomized, placebo-controlled double-blind trial is to evaluate the effect of acetazolamide on right heart function at rest in lowlanders with chronic obstructive pulmonary disease (COPD) traveling to high…
- Conditions
- Right Heart Function, Chronic Obstructive Pulmonary Disease, Altitude Sickness
- Trial name
- NCT04915365
- Testing
- Acetazolamide
- Where
- Kyrgyzstan
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Altitude Hypoxia
Effect of Acetazolamide on Lung Water Content by Ultrasound in Lowlanders Older Than 40 Years at Altitude
Randomized, placebo controlled trial evaluating the effect of acetazolamide on lung water content by ultrasound in lowlanders older than 40 years travelling from 760 m to 3'100 m.
- Trial name
- NCT03539367
- Testing
- ACETAZOLAMIDE oral capsule
- Where
- Kyrgyzstan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hypertension, Pulmonary
Effect of Exercise Training in Patients With Pulmonary Hypertension
Pulmonary Hypertension (PH) is a serious disease with a dismal prognosis when left untreated. Advances in medical therapy have improved survival according to recent registries and systematic reviews, but are associated with high…
- Trial name
- NCT02558582
- Testing
- respiratory and exercise therapy, respiratory and exercise therapy with supplemental oxygen
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- University of Zurich
Vaginal Tear, Perineal Tear
Application of a Perineal Protection Device in Vacuum-assisted Births
Visible birth tears are common in vaginal births, especially in vacuum-assisted births. One aim of obstetrical work is to minimize such injuries by an adequate birth management , for example with a proper perineal support.
- Trial name
- NCT04370340
- Testing
- BabySlide
- Where
- Switzerland
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Breast Cancer, Implants
Diagnostic Performance of an Automated Breast Ultrasound System (ABUS)
The purpose of this study is to evaluate the diagnostic performance of a new ABUS system among 4 different population: Population A: women undergoing screening for familial or genetic predisposition for breast cancer.
- Trial name
- NCT02661204
- Testing
- Automated breast ultrasound examination (ABUS)
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- University of Zurich
Stroke, Ischemic
Perfusion Augmentation Through Exercise
Large cerebral vessel occlusion is a common phenomenon in the general population and accounts for 13-35% of ischemic strokes. Chronic stenosis in the large cerebral arteries is associated with cerebral hypoperfusion, cognitive…
- Trial name
- PERFEX (NCT05584605)
- Testing
- Aerobic treadmill training, Stretching exercise
- Where
- 3 sites in Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Pain, Acute
Developing an Objective Measure of Experienced Pain
Pain is a public health challenge around the world. However, there is no single standardized measure of pain, to the point that the estimated prevalence of chronic pain in adults ranges between 2% and 64% depending on the methods…
- Trial name
- NCT05415423
- Testing
- Developing an objective measure of experienced pain
- Where
- Switzerland
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Motor Control in Incomplete Spinal Cord Injured Persons
Effects of Transcutaneous Spinal Cord Stimulation on Residual Voluntary Motor Control in Individuals With Incomplete Spinal Cord Injury
Recently, a transcutaneous protocol of electrical spinal cord stimulation (tSCS) has been developed. It was suggested, that this method could be used to improve the therapy process after a spinal cord injury (SCI).
- Trial name
- NCT03137108
- Testing
- Transcutaneous electrical spinal cord stimulation
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University of Zurich
Hematoma, Subdural, Chronic, Hematoma, Subdural, Intracranial
Covers to Improve Esthetic Outcome After Surgery for Chronic Subdural Hematoma
The clinical-functional result after frontal and parietal burr-hole trepanation for the treatment of chronic subdural hematoma (cSDH) is effective with regards to control of the hematoma and regression of symptoms (headache…
- Conditions
- Hematoma, Subdural, Chronic, Hematoma, Subdural, Intracranial, Haematoma;Subdural;Traumatic
- Trial name
- CORRECT-SCAR (NCT03755349)
- Testing
- Placement of burr-hole covers, No placement of burr-hole covers
- Where
- Switzerland
- Volunteers
- 83 people
- Sponsor
- University of Zurich
Fertility Disorders, Early Pregnancy
Cycle and Pregnancy Monitoring With Wearable Sensor Technology (AVA)
In this study physiological data is measured using wearable sensors as well as hormonal and ultrasound measurements of growing follicles/ ovulation in a group of endocrinologically healthy women with regular cycles, who aim for a…
- Trial name
- SUSAVA (NCT03161873)
- Testing
- Ava
- Where
- Switzerland
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Normal Body Weight, Obesity
Endocrine and Neural Control of Eating in Women
The purpose of this study is to better understand how female sex hormones influence the food intake in the gut system through the release of satiety hormones as well as through central regulative mechanisms in the brain that…
- Trial name
- NCT02994420
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Endometriosis, Quality of Life
Quality of Life in Endometriosis - a Case Control Study
Endometriosis, one of the most common diseases of women during their reproductive period., may present a chronic disabling disease with major impact on women's life.
- Conditions
- Endometriosis, Quality of Life, Pain, Sexuality
- Trial name
- NCT02511626
- Where
- Switzerland
- Volunteers
- 1,267 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Gait Disorders, Neurologic, Gait Disorder, Sensorimotor
Gait Adaptability: Tracking Locomotor Recovery After Incomplete Spinal Cord Injury
Adaptive gait assessements will be evaluated as a potential new marker for tracking locomotor recovery throughout rehabilitation of spinal cord injury subjects.
- Trial name
- NCT03343132
- Testing
- Standard locomotor therapy
- Where
- Switzerland
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Neurological Movement Disorders
Probing Neural Circuitry for the Control of Movement
The investigators are interested in examining 1) the basic organization of spinal and cortical circuitry for the control of movement and 2) the influence of injury of these circuits.
- Trial name
- NCT02150642
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Zurich
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