Clinical trials: sponsored by University of Zurich
Spinal Cord Injury, Stroke
Interactive Motor Imagery in Virtual Reality
This project will build and test the first rehabilitation system employing virtual reality (VR)-based observation, motor imagery and execution to treat lower-limb neuropathic pain and motor dysfunction in participants with an…
- Trial name
- NCT02149186
- Testing
- iCTuS-L
- Where
- Switzerland
- Volunteers
- 79 people
- Sponsor
- University of Zurich
Pulmonary Hypertension
Acute Exposure to High Altitude on Exercise Capacity
Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to High Altitude (2500m above sea level) in constant loaded exercise capacity.
- Trial name
- NCT03637153
- Testing
- Assessment at Low Altitude (470m above sea level), Exposure to High Altitude (2500m above sea level)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Pulmonary Hypertension
Acute Exposure to High Altitude on Pulmonary Artery Pressure and Right Heart Function (Echo) Under Exercise
Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to High Altitude (2500m above sea level) on pulmonary artery pressure and right heart function (Echo) under exercise.
- Trial name
- NCT03637179
- Testing
- Assessment at Low Altitude (470m above sea level), Exposure to High Altitude (2500m above sea level)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Vestibular
Prospective Assessment of Peripheral-vestibular Function After Skull Base Surgery
Due to its localization in the cerebello-pontine angle, the vestibulo-cochlear nerve is at risk to damage during surgery performed nearby.
- Trial name
- NCT02773277
- Testing
- head-impulse testing
- Volunteers
- 10 people
- Sponsor
- University of Zurich
Verticality Perception in Stroke
Verticality Perception in Stroke Patients
The long-term goal of this research is to advance our knowledge of how information from the labyrinth is brought to perception and how adaptation to vestibular imbalance influences spatial orientation.
- Trial name
- NCT02184923
- Testing
- presentation of visual vertical
- Where
- Switzerland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pulmonary Hypertension
Acute Exposure of High Altitude on Cardiac Output
Randomized crossover trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response High Altitude (Säntis; 2500m above sea level) on non-invasive cardiac output assessments by Finapres® NOVA Technology at…
- Trial name
- NCT03637218
- Testing
- Assessment at Low Altitude (470m above sea level), Exposure to High Altitude (2500m above sea level)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
COPD
Impact of Walking Behind the COPD Patient on 6MWD
The six-minute walk test (6MWT) is a well established field exercise test to assess the functional exercise capacity in chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT04033783
- Testing
- 6MWT - accompanied, 6MWT - not accompanied
- Where
- 2 sites in Switzerland
- Volunteers
- 49 people
- Sponsor
- University of Zurich
Sleep Disturbance, Sleep Disorder
Sleep in Psychiatric Inpatients
Decades of research have shown that sleep disturbances are common among patients with a wide range of psychiatric disorders. Such reported sleep disturbances include disrupted sleep efficiency and continuity, sleep quality…
- Conditions
- Sleep Disturbance, Sleep Disorder, Insomnia, Hypersomnia
- Trial name
- SPIN (NCT04201392)
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Nightmare, Psychiatric Disorder
Psychiatric Inpatient Nightmare Treatment
Nightmares are repeated extremely dysphoric and well-remembered dreams, which typically occur during REM sleep in the second half of sleep, may awaken the dreamer, and upon awakening, individuals quickly become oriented and…
- Trial name
- PINIT (NCT04198142)
- Testing
- Imagery Rehearsal Therapy, Treatment as Usual with dream diaries
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Esophageal Cancer, Surgery--Complications
Preemptive Endoluminal Negative Pressure in Minimally Invasive Transthoracic Esophagectomy
The primary objective of the preSponge randomized controlled trial (RCT) will be to assess the potential protective effects of preemptive endoscopic negative pressure therapy (ENP) on postoperative morbidity in high-risk patients…
- Conditions
- Esophageal Cancer, Surgery--Complications, Leak, Anastomotic
- Trial name
- NCT04162860
- Testing
- Eso-SPONGE® device
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Adenocarcinoma, Circulating Tumor Cells
CTC Pancreatic Adenocarcinoma
Proportion of circulating tumor cells (CTC) in the postoperative phase after curative tumor removal of pancreatic cancer will be determined and correlated to the accordance of anesthesia (desflurane versus propofol)
- Conditions
- Adenocarcinoma, Circulating Tumor Cells, Pancreatic Neoplasms
- Trial name
- NCT02335151
- Testing
- Desflurane
- Where
- 4 sites in Switzerland
- Volunteers
- 86 people
- Sponsor
- University of Zurich
Animal Assisted Therapy
Efficacy of Equine Assisted Therapy on Negative Symptoms in Patients With Schizophrenia
The main object of this study is to evaluate the efficacy of equine assisted therapy on substantial and so far unsatisfactorily treatable symptom complexes in patients with schizophrenia.
- Trial name
- STABLE (NCT03935243)
- Testing
- equine assisted therapy, activating control phase
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- University of Zurich
Chronic Pain, Spirituality
Spiritual Assessment in Chronic Pain Patients
The World Health Organization's (WHO) understanding of health(care) is incrementally incorporating the spiritual dimensions equivalent to the physical, psychological and social ones.
- Trial name
- NCT03679871
- Testing
- Questionnaire validation
- Where
- 6 sites in Switzerland
- Volunteers
- 225 people
- Sponsor
- University of Zurich
Coronary Arteriosclerosis, Endothelial Function
Paracetamol and Endothelial Function in Patients With Stable Coronary Artery Disease
The purpose of this study is to determine the effect of orally given paracetamol on the vascular function and on 24-hour blood pressure in patients with coronary artery disease
- Trial name
- NCT00534651
- Testing
- Paracetamol
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- University of Zurich
Prenatal Anxiety, Generalized Anxiety
Willkommen Mutterglück: Online CBT for Pregnant and Postpartum Women With Depression and Anxiety
This intervention study aims to evaluate the effectivity of web-based cognitive therapy in reducing depression and anxiety in pregnant and postpartum women.
- Conditions
- Prenatal Anxiety, Generalized Anxiety, Postpartum Depression, Major Depressive Disorder
- Trial name
- NCT04183946
- Testing
- Online Cognitive Behavioural Therapy
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- University of Zurich
General Population
Monitoring of Biomarkers by Portable Breath Gas Sensors: an Exploratory Study
Breath analysis is a non-invasive procedure to detect and monitor diseases and it is particularly attractive for patients who have to routinely check biomarkers, such as diabetics (blood glucose) or end-stage renal disease…
- Trial name
- NCT02685241
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Coronary Artery Disease
Ultra Low Dose CT for CACS and AC of SPECT
The aim of the study is to compare the CACS obtained from standard dose CT to the CACS obtained from ultra-low-dose scans. Additionally, the usefulness of ultra-low-dose CT for AC of myocardial perfusion SPECT will be assessed.
- Trial name
- NCT02458352
- Testing
- Ultra low dose non-contrast enhanced CT, Standard dose non-contrast enhanced CT
- Where
- Switzerland
- Volunteers
- 105 people
- Sponsor
- University of Zurich
High Altitude Pulmonary Hypertension
Cerebral Tissue Oxygenation in Highlanders/Lowlanders
The purpose of the current study is to evaluate the cerebral tissue oxygenation of Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a longitudinal cohort study.
- Trial name
- NCT03172429
- Where
- Kyrgyzstan
- Volunteers
- 79 people
- Sponsor
- University of Zurich
High Altitude Pulmonary Hypertension
Right Ventricular Function During Exercise in Highlanders/Lowlanders
The purpose of the current study is to evaluate the right ventricular function during graded cycling on an ergometer by transthoracic echocardiography in Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by…
- Trial name
- NCT03165032
- Where
- Kyrgyzstan
- Volunteers
- 173 people
- Sponsor
- University of Zurich
Chronic Obstructive Pulmonary Disease
Effect of Acetazolamide on Exercise Performance in Patients With Respiratory Disease at Altitude
In this trial, the investigators will evaluate the effect of acetazolamide (375 mg per day) vs. placebo on exercise performance at altitude in patients with COPD.
- Trial name
- NCT03177837
- Testing
- ACETAZOLAMIDE oral capsule
- Where
- Kyrgyzstan
- Volunteers
- 176 people
- Sponsor
- University of Zurich
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.