Clinical trials: sponsored by University of Zurich
Chronic Disease, Illness Behavior
Couples Coping With Multiple Chronic Medical Conditions
Handling of complex health situations (as defined by multimorbidity) in partnership: communication between romantic partners; subjective illness perception; coping with stressful experiences due to multimorbidity.
- Trial name
- GUGKS (NCT01912157)
- Testing
- Expressive Writing
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- University of Zurich
Sleep Apnea, Obstructive
Effects of Suboptimal CPAP Therapy on Symptoms of Obstructive Sleep Apnoea
Obstructive sleep apnoea (OSA) is a highly prevalent sleep-related breathing disorder. The most effective treatment for OSA is continuous positive airway pressure (CPAP).
- Trial name
- NCT02781740
- Testing
- Continous Positive Air Pressure Device
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Dementia, Oral Hygiene
Oral Health, Bite Force and Dementia
Study aims: The primary aim is to identify influencing variables on oral hygiene / oral health and bite force in patients with dementia.
- Conditions
- Dementia, Oral Hygiene, Chewing Problem
- Trial name
- OrBiD (NCT03775772)
- Testing
- Oral Health, Bite Force
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Color Perception
Evaluation of Different Color Vision Tests in Children
The purpose of this study is to investigate which clinical colour vision assessment fits best for preschool children and school children.
- Trial name
- NCT02464241
- Testing
- only examination
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Intraventricular Hemorrhage of Prematurity
Erythropoietin for the Repair of Cerebral Injury in Very Preterm Infants
The purpose of this randomized and placebo-controlled EpoRepair trial is to evaluate the effect of intravenously administered recombinant human erythropoietin (Epo) as compared to placebo in preterm infants with brain damage on…
- Trial name
- EpoRepair (NCT02076373)
- Testing
- recombinant human Erythropoietin
- Where
- 8 sites in Austria, Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Effect of High Altitude
Effect of High Altitude Exposure, Acclimatization and Re-exposure on Nocturnal Breathing Pattern in Lowlanders
Prospective interventional trial in lowlanders evaluating the effect of acute exposure, acclimatization and re-exposure of high altitude on nocturnal breathing pattern.
- Trial name
- NCT02730143
- Testing
- Altitude exposure
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Polytrauma, Psychological Distress
Psychological Distress in Relatives of Severely Injured Patients
Patients who have sustained and survived a polytrauma do heavily depend on the support and functioning of their family. This is only possible if the family members are physically and mentally able to cope with the situation.
- Conditions
- Polytrauma, Psychological Distress, Relatives
- Trial name
- NCT03137420
- Testing
- Numeric Scale of Family Distress
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Prolonged Grief Disorder
Measurement and Assessment of Prolonged Grief Disorder in Asia
The overall project includes three sub-studies. Sub-Study I aims to develop the content of a new cultural sensitive grief questionnaire (International Prolonged Grief Disorder Scale, IPGDS Killikelly and Maercker, 2018) through…
- Trial name
- MAP Asia (NCT03568955)
- Testing
- International Prolonged Grief Disorder Scale (IPGDS)
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Zurich
Heart Failure
Differential Gene Expression in Patients With Heart Failure and Iron Deficiency - Effects of Ferric Carboxymaltose
The primary efficacy objective of this study is to evaluate the effect of ferric carboxymaltose on mitochondrial gene activation pattern after 12 weeks of treatment.
- Trial name
- NCT01978028
- Testing
- ferric carboxymaltose
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Focus of Study: Higher Cognition and the Vestibular System
The Influence of GVS on Mental Transformation
Corroboratory behavioral evidence showed interaction effects between vestibular stimulation and egocentric transformation. The investigators here examine in healthy participants, whether there are shared brain mechanisms…
- Trial name
- NCT02979314
- Testing
- Galvanic Vestibular Stimulation
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Effects of High Altitude
Acclimatization of Healthy Subjects During a Stay at 3200 m
The study evaluates respiratory acclimatization in healthy lowlanders staying for 3 weeks at 3200 m.
- Trial name
- NCT02451020
- Testing
- Altitude exposure
- Where
- Kyrgyzstan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hand Injuries
Three-dimensional Kinematic Motion Analysis of Finger and Wrist During Daily Activities
Development of reliable and objective evaluation methods is required for natural upper-extremity tasks. Three-dimensional imaging measurement techniques are a powerful tool for quantitative assessment of multijoint movements.
- Trial name
- NCT02890862
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Vertebral Fracture, Cement Augmentation
Assessing Cement-bone Incorporation and Adjacent Segment Degeneration Following Cement Augmentation; an MRI-PET Follow-up
3-year PET-MRI follow-up after vertebral balloon kyphoplasty aiming to investigate cement incorporation.
- Trial name
- NCT03369288
- Testing
- PET MRI
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstructive Sleep Apnoea (OSA), Exhaled Breath
Mass Spectral Fingerprinting in Obstructive Sleep Apnoea
To answer the question whether a previously detected breath profile in patients suffering from obstructive sleep apnoea (OSA) can be found in a cohort of patients with suspected OSA using mass spectrometry (validation study).
- Conditions
- Obstructive Sleep Apnoea (OSA), Exhaled Breath, Mass Spectrometry
- Trial name
- NCT02810158
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Depression
Effectiveness and Cost-effectiveness of Telephone-delivered Psychotherapy for Depression in Primary Care
The aim of the study is the examination of effectiveness and cost-effectiveness of a telephone-based psychotherapy (Tel-PT) for depression compared to treatment as usual in primary care.
- Trial name
- NCT02667366
- Testing
- Tel-PT, TAU and text messages
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- University of Zurich
Melanoma
Pilot Study Investigating the Metabolic Activity and Transcriptional Profiling in Vivo in Tumor Biopsies in Melanoma Patients During Treatment With Pazopanib Alone and in Combination With Paclitaxel
This is an open, monocentric, pilot study to determine the metabolic activity (glucose-uptake) in vivo during monotherapy with pazopanib in comparison to combination therapy with pazopanib plus paclitaxel and to investigate the…
- Trial name
- NCT01666418
- Testing
- Pazopanib/Paclitaxel
- Where
- Switzerland
- Volunteers
- 19 people
- Sponsor
- University of Zurich
Laser Burn, Gingival Disease
Comparison of Sample Biopsy Using Scalpel or Er:YAG Laser
For certain changes in the oral mucosa a histopathological examination of the affected tissue is indicated to confirm the diagnosis. The gold standard is the biopsy by scalpel.
- Conditions
- Laser Burn, Gingival Disease, Biopsy Wound
- Trial name
- NCT03638973
- Testing
- Biopsy
- Where
- Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Empty Nose Syndrome
Trigeminal Endonasal Perception: A Predictor for Septoplasty Outcome
This study investigates wether patients with increased trigeminal perception threshold and low expression of TRP channels have more often nasal blockage despite functionally successful nasal surgery (TRP channel = transient…
- Trial name
- NCT02230423
- Testing
- Nasal surgery
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University of Zurich
Monotherapy, Dolutegravir
Early Simplified: A Trial to Compare the Efficacy of Standard of Care Combination Antiretroviral Therapy With a Simplified Dolutegravir Monotherapy in Patients With a Primary HIV-1 Infection
Long term toxicity of combination antiretroviral therapy (cART) is a substantial contributor to morbidity and mortality in chronically infected HIV positive individuals.
- Conditions
- Monotherapy, Dolutegravir, Primary HIV Infection, Treatment Efficacy
- Trial name
- NCT02551523
- Testing
- Dolutegravir, Standard of care combinational antiretroviral therapy
- Where
- Switzerland
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Glaucoma
Non-Contact Air Tonometry (Topcon CT-1®) Versus Goldmann
In this prospective device comparison study with 58 healthy eyes, the Topcon CT-1® showed statistically significant elevated intraocular pressure measurements compared to the gold standard Goldmann application tonometry.
- Trial name
- NCT03684174
- Testing
- Intraocular pressure measurement
- Where
- Switzerland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Zurich
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