Clinical trials: sponsored by University of Zurich
Adverse Drug Reactions
Collection, Evaluation and Assessment of Adverse Drug Reactions on the Oncology Ward
The proposed cohort study collected within a 5-month observation period adverse drug reaction (Adverse Drug Events - ADE) in patients at the Department of Oncology at the University of Zurich.
- Trial name
- NCT01058122
- Testing
- Collection of adverse drug events
- Where
- Switzerland
- Volunteers
- 129 people
- Sponsor
- University of Zurich
PTSD
Reconsolidation and EMDR
Blocking of reconsolidation by pharmacological or behavioral means offers the therapeutic possibility of weakening traumatic memories in posttraumatic stress disorder (PTSD).
- Trial name
- NCT02572830
- Testing
- Delayed Bilateral Eye Movements, Undelayed Bilateral Eye Movement
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Outcome
Immediate Post-operative Recovery After Regional vs. General Anesthesia
Early post-anesthesia status of patients emerging from surgery encompasses vital respiratory and hemodynamic parameters as well as subjective signs of well-being such as absence of nausea, vomiting and a low pain level.
- Trial name
- NCT03047148
- Testing
- Data mining from records
- Where
- Switzerland
- Volunteers
- 1,880 people
- Sponsor
- University of Zurich
Stroke
INTERACTION, Monitoring of Stroke Patients in Hospital and Home Environment
Clinical assessment and monitoring of balance and arm function in stroke patients with sensor based measurement, in clinical and home environment.
- Trial name
- INTERACTION (NCT02118363)
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Respiratory Amplitude
Influence of Couch Tracking Motion
Tumor motion increases the uncertainty in Radiation Oncology. Couch tracking can compensate for this uncertainty. However it is not known if the couch motion influences the respiratory pattern of the patients.
- Trial name
- NCT02820532
- Testing
- Protura Treatment table
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pulpitis
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation
The purpose of this study is to determine whether dentinal fluid (tooth fluid) of teeth with or without a painful inflammatory condition in their nerve (pulp) contain inflammatory marker.
- Trial name
- NCT02967081
- Testing
- Collection of dentinal fluid using a cellulose membrane
- Where
- Switzerland
- Volunteers
- 67 people
- Sponsor
- University of Zurich
Sleep Apnea, Obstructive
The Effects of CPAP Withdrawal on Cerebral Vascular Reactivity and Brain Oxygenation in OSA
Obstructive sleep apnoea (OSA) is a highly prevalent sleep-related breathing disorder associated with adverse cardiovascular outcome. Underlying mechanisms are subject of debate.
- Trial name
- NCT02493673
- Testing
- Continuous positive airway pressure device
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- University of Zurich
COPD
Breath Analysis in Chronic Obstructive Lung Disease (COPD)
To answer the question whether a disease specific profile of breath in patients with COPD can be detected by an untargeted metabolomic study using exhaled breath analysis by mass spectrometry.
- Trial name
- NCT02186639
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hypersensitivity
Methodological Study to Compare the Effect of Different Methods of Measuring Cat Allergy Symptoms in Patients That Have Immunized Their Cats With FEL-CMV.
In this Project we will monitor the symptoms of cat allergic participants who live together with a cat which is immunized with FEL-CMV using the novel symptom recording method "HypoScore", a General weekly symptom score, and a…
- Trial name
- NCT03089788
- Testing
- Home-based test, Skin test
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Severe Tricuspid Regurgitation
International Multisite Transcatheter Tricuspid Valve Therapies Registry
For a long time, tricuspid valve disease has been considered as less important than left-sided valvular heart disease. If treated in an advanced stage and simultaneously with other cardiac diseases, it is associated with…
- Trial name
- TriValve (NCT03416166)
- Testing
- Transcatheter Tricuspid Intervention
- Where
- Switzerland
- Volunteers
- 269 people
- Sponsor
- University of Zurich
Refractory Neurogenic LUTD
Sacral Neuromodulation for Neurogenic LUT Dysfunction
Prospective, randomized, placebo-controlled, double-blind multicenter trial including 4 tertiary sacral neuromodulation referral centers in Switzerland (Zürich, Bern, Nottwil, St.Gallen).
- Trial name
- NCT02165774
- Testing
- Turning OFF the neuromodulator, Turning ON the neuromodulator
- Where
- 4 sites in Switzerland
- Volunteers
- 61 people
- Sponsor
- University of Zurich
Ulcerative Colitis, Flare Up, Symptom
Real-world Data Regarding Treatment of Ulcerative Colitis Patients With Golimumab
TNF inhibitors have improved treatment options for patients with inflammatory bowel disease (IBD) and three TNF inhibitors, infliximab, adalimumab and golimumab are available for treatment of ulcerative colitis in Switzerland.
- Trial name
- NCT03394586
- Testing
- Exposure to golimumab
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Local Infiltration, Anesthesia
Painless Local Anaesthesia With Bicarbonate Admixture
This study examines whether the injection of local anesthesia mixed with sodium bicarbonate in the ratio of 3:1 creates a less burning sensation and is as effective regarding the anesthetic effect as in the ratio of 9:1.
- Trial name
- NCT03238625
- Testing
- Lidocaine and sodium bicarbonate, Lidocaine, Sodium cloride 0.9%
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Spinal Cord Injury
Validation of a Novel Robot-aided Assessment of Gait Ability
The aim of this study is the validation of a novel gait assessment method implemented in the Lokomat gait trainer with respect to established clinical gait assessment methods.
- Trial name
- NCT02425332
- Testing
- Lokomat gait trainer
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Severely Burned Patients
HLA Sensitization in Severely Burned Patients
Primary goal of this study is the analysis of HLA (Human leucocyte antigen) formation in severly burned patients. Potential HLA triggers in the treatment of severely burned patients are blood products, assist devices or temporary…
- Trial name
- NCT02537821
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Difficult Intubation
Visualization of the Intubation Pathway With the "IRRIS"-Device
A prospective, open label, non-randomized, single centre safety and feasibility study. Patients with no expected airway difficulties scheduled for elective surgery including tracheal intubation and general anesthesia procedures…
- Trial name
- IRRIS (NCT03234283)
- Testing
- IRRIS InfraRed - Red Intubation System
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Chronic Depressive Disorder
Development of a Telephone-based Continuation Treatment for Patients With Chronic Depression.
There is a high risk for relapse in people suffering from depression. Studies indicate that the continuation of an acute psychotherapeutic treatment can reduce the likelihood of relapse.
- Trial name
- NCT02397850
- Testing
- phone calls 30 min, phone calls 50 min
- Where
- Switzerland
- Volunteers
- 7 people
- Sponsor
- University of Zurich
Healthy, Schizotypal Personality
Exceptional Experiences (EE), Salience & Dopaminergic Neurotransmission
The dopamine hypothesis of schizophrenia implies that alterations in the dopamine system cause functional abnormalities in the brain that may converge to aberrant salience attribution and eventually lead to psychosis.
- Trial name
- NCT03333369
- Testing
- 200 mg levodopa/50 mg benserazide, Dextrose
- Where
- Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Alzheimer Disease
Cognitive-Behavioral Treatment for Mild Alzheimer's Patients and Their Caregivers
The purpose of this study is to determine whether a comprehensive cognitive-behavioral therapy-based, multi-component treatment programme is effective in the treatment of neuropsychiatric symptoms of patients with mild…
- Trial name
- CBTAC (NCT01273272)
- Testing
- Comprehensive, CBT-based, multi-component treatment, Treatment as usual
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Oropharyngeal Cancer, Hypopharyngeal Cancer
A Phase II Study In Patients With Advanced Head And Neck Cancer Of Standard Chemoradiation And Add-On Cetuximab
Sixty patients with advanced squamous cell carcinomas of the head and neck will be enrolled in this study. Patients are treated with standard chemoradiation in combination with concurrent add-on cetuximab.
- Conditions
- Oropharyngeal Cancer, Hypopharyngeal Cancer, Laryngeal Cancer
- Trial name
- NCT01435252
- Testing
- Cetuximab
- Where
- Switzerland
- Volunteers
- 68 people
- Sponsor
- University of Zurich
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