Clinical trials: sponsored by University of Zurich
Regeneration Potential of Healthy Old Men in Terms of Satellite Cell Activation
Influence of Consecutive Strength- and Endurance Regimes on the Myonuclear Domain and Satellite Cell in the M. Vastus Lateralis of Old Healthy Men
Randomised training intervention. Influence of consecutive training regime on the impact of the myonuclear domain and satellite cell Sarcopenia Despite that the muscle mass can be positively influenced by training, the loading…
- Trial name
- NCT01905345
- Testing
- Training
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sickle Cell Disease
Clinical Trial to Study the Safety and Tolerability of Memantin Mepha® in Sickle Cell Disease Patients
Symptomatic sickle cell disease is worldwide the most frequent cause for hereditary hemolytic anemia with recurrent pain crisis.
- Trial name
- MemSID (NCT02615847)
- Testing
- Memantinhydrochlorid
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University of Zurich
Genital Ulcer Disease (GUD)
New Multiplex Real-time PCR for Genital Ulcer Disease
(i) To compare a new diagnostic PCR with established diagnostic procedures for T. pallidum (serology, dark field microscopy), H. ducreyi (cultivation), HSV types 1 and 2 (cultivation, PCR).
- Trial name
- NCT01688258
- Testing
- Diagnostic swab
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Glaucoma, Cataract
Phaco vs. Phaco-ELT vs. Phaco-Trabectome 12m
This study compares efficacy (i.e. IOP and hypotensive medications) of phaco alone vs. combined phaco plus excimer laser trabeculotomy vs. combined phaco plus trabectome.
- Trial name
- NCT01194310
- Testing
- phaco, phaco-ELT, phaco-Trabectome
- Where
- Switzerland
- Volunteers
- 245 people
- Sponsor
- University of Zurich
Changes in Gut Microbiota Composition After Lactulose Exposure
Elucidating the Influence of Lactulose Intake on the Gut Microbiota Composition
This study will test the influence of lactulose of the human gut microbiota. Healthy volunteers will ingest 50g of lactulose and donate stool samples 1 day before as well as 1-2 days and 14 days after the test.
- Trial name
- Lactulose (NCT02397512)
- Testing
- application of lactulose, application of sucrose
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Glaucoma
Goldmann Applanation Tonometry, Dynamic Contour Tonometry, and Corvis ST Tonometer
The study is investigating Intra ocular pressure (IOP) by Goldmann Applanation Tonometry, Dynamic Contour Tonometry, and the Corvis ST tonometer.
- Trial name
- NCT02624427
- Testing
- Measurement of intraocular pressure (IOP)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Metastatic Cancer, Mobile Health
Mobile Health Technology for Palliative Care Patients
To test the potential and acceptance of wireless activity tracking in palliative care patients leaving hospital care. Explorative study, collaboration project of the Clinic of Radiation-Oncology, University Hospital Zurich and…
- Conditions
- Metastatic Cancer, Mobile Health, Chronic Disease
- Trial name
- NCT03038841
- Testing
- Mobile Health
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Open Angle Glaucoma, Ocular Hypertension
Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy
The aim of this study is to evaluate the efficacy of selective laser trabeculoplasty after a prior failed phacoemulsification and Eximer Laser Trabeculectomy.
- Conditions
- Open Angle Glaucoma, Ocular Hypertension, Cataract
- Trial name
- SLT (NCT02434250)
- Testing
- Selective Laser Trabeculoplasty
- Where
- Switzerland
- Volunteers
- 203 people
- Sponsor
- University of Zurich
Glaucoma
Incidence of Dyschromatopsia in Glaucoma
Incidence of dyschromatopsia
- Trial name
- NCT02966678
- Testing
- Color Vision Test
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Depression
Mobile Sensing and Support for Depression
The objective of this study is two fold, first to explore the potential of context sensitive intervention delivery to provide in-situ support for people with depressive symptoms, second to explore the detection of daily-life…
- Trial name
- MOSS (NCT02776839)
- Testing
- Mobile sensing
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Zurich
PSA
Altered PSA Test Due to Possible Suspected Heterophilic Antibodies
The purpose of this study is to investigate if clinically non explainable high or low Prostate-specific antigen (PSA) levels are associated with heterophilic antibodies in the serum of participants.
- Trial name
- NCT02455466
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Ganglion Cells
Retinal Ganglion Cell Layer in Patients With Intracerebral Processes
Transsynaptic degeneration of the retinogeniculate pathways is well documented to occur in nonhuman primates when the cerebral lesion occurs even during adulthood.
- Trial name
- NCT02407886
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Chronic Obstructive Pulmonary Disease (COPD)
Altitude Related Illness In Patients With Respiratory Disease
Randomized, placebo controlled trial evaluating efficacy of dexamethasone in preventing acute mountain sickness in lowlanders with chronic obstructive lung disease travelling from 700 m to 3200 m.
- Trial name
- NCT02450968
- Testing
- Dexamethasone
- Where
- Kyrgyzstan
- Volunteers
- 124 people
- Sponsor
- University of Zurich
Ehler's Danlos Syndrome, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Children and Adolescents With Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
- Trial name
- NCT02712060
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Food Allergy
iFAAM: The Impact of Proton-pump Inhibitors (Antacids) on Threshold Dose Distributions
In patients with a walnut allergy double blind placebo controlled food challenge with walnut will be combined with the intake of proton pump inhibitor (PPI) or with placebo to assess the impact of PPI on threshold level and on…
- Trial name
- iFAAM-PPI (NCT02552537)
- Testing
- Omeprazole
- Where
- 2 sites in Spain, Switzerland
- Volunteers
- 44 people
- Sponsor
- University of Zurich
Food Allergy
Molecular Analysis of IgE Antibodies in Walnut Allergic Patients
Accurate diagnosis of food allergy depends on the identification of the causative allergenic molecule(s). The proposed study intends to investigate and compare the pattern of IgE antibody sensitisation in walnut allergic subjects…
- Trial name
- NCT02295267
- Testing
- walnut allergy provocation
- Where
- Switzerland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Food Allergy
Integrated Approaches to Food Allergen and Allergy Risk Management
Patients with history of a food allergy to hazelnut, walnut or celeriac will undergo food provocation with a dose of the allergenic food to which 5% of the respective food allergic population (ED05) has been calculated to respond…
- Trial name
- iFAAM (NCT02295397)
- Testing
- food
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cystic Fibrosis
Effect of a Nursing Program for Patients With Cystic Fibrosis on Disease Management
The purpose of this study is to evaluate the effect of a nursing program in patients with cystic fibrosis.
- Trial name
- NCT02286050
- Testing
- CF Nursing Program
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University of Zurich
Quality of Life
The Butler-Program 2.0: An Internet Platform for Elderly
In this study, effectiveness of an internet based intervention (Butler 2.0) for elderly is tested. Participants (n= 60) will be randomly assigned to two different groups (intervention vs. waitlist).
- Trial name
- NCT02816801
- Testing
- Butler-Program 2.0
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Abdominal Aortic Aneurysm, Deep Vein Thrombosis
Evaluation of a New Imagingtechnologie for Thrombosis
Arterial and venous thrombi play an important role in various vascular diseases such as myocardial infarction, stroke, transient ischemic attacks (TIA) and pulmonary embolism.
- Trial name
- PET-GP1_1 (NCT02469376)
- Testing
- [18F]-GP1
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- University of Zurich
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