Clinical trials: sponsored by University of Zurich
Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue, Pyoderma Gangrenosum
Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
This study investigates the genetic architecture of Neutrophil-Mediated Inflammatory Skin Diseases. After collecting informed consent, all patients' clinical phenotype is graded at inclusion with a detailed case report form and a…
- Conditions
- Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue, Pyoderma Gangrenosum, Erosive Pustular Dermatosis of the Scalp, Sweet's Syndrome
- Trial name
- NEUTROGENE (NCT01952275)
- Testing
- Collection of biological samples
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- University of Zurich
Acute Coronary Syndromes
Inflammation and Acute Coronary Syndromes
Subproject 1: Optimize prevention after acute coronary syndromes (ACS) by improving caregiver and patient education (http://elips.hug-ge.ch/eng/index_eng2.htm) Subproject 2: Discover novel genomic biomarkers of ACS in leukocyte…
- Trial name
- SPUM-ACS (NCT01000701)
- Where
- 4 sites in Switzerland
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Mitral Valve Insufficiency
High and Intermediate Risk Degenerative Mitral Regurgitation Treatment: A Trial Comparing MitraClip® to Surgical Therapy
The study is comparing MitraClip® to Surgical therapy in high and intermediate risk patients, who should be older than 18 years, and shall evaluate safety and efficacy of MitraClip® vs.
- Trial name
- HiRiDe (NCT02534155)
- Testing
- MitraClip®, Mitral valve Surgery
- Where
- 12 sites in Germany, Italy and 1 more
- Volunteers
- 294 people
- Sponsor
- University of Zurich
Polycystic Ovary Syndrome, Endometriosis
Mathematical Model for the Human Menstrual Cycle, Endocrinological Diseases and Fertility Treatment-PAEON
Development of a bio-mathematical model of the human female cycle
- Conditions
- Polycystic Ovary Syndrome, Endometriosis, Hyperprolactinemia
- Trial name
- PAEON (NCT02098668)
- Testing
- Fertility treatment
- Where
- Switzerland
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension, Chronic Cardiorespiratory Disease
Effect of Short-term Oxygen During CPET in Pulmonary Hypertension
In a randomized, sham-controlled trial the investigators will test whether supplemental oxygen given during cardiopulmonary exercise testing will improve exercise performance and physiological parameters in patients with…
- Trial name
- ExOx-CPET (NCT01748474)
- Testing
- Supplemental oxygen via a mask
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Squamous Cell Carcinoma
Aggressive Squamous Cell Carcinoma in Organ Transplant Recipients
To identify risk factors for aggressiveness in Squamous Cell Carcinoma of the skin in organ transplant recipients.
- Trial name
- NCT02095912
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Skin Toxicity
Serum 25-OH Vitamin D Modulation by Sunbed Use According to EU Guideline EN 60335-2-27
Our study aims to clarify the impact of the use of a standard sunbed according to new EU guideline EN 60335-2-27 and possibly discount the positive effects of tanning beds.
- Trial name
- NCT01976481
- Testing
- sunbed exposure
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- University of Zurich
Inflammatory Bowel Disease
The Altitude Inflammatory Bowel Disease Study
This is a prospective, controlled and observational study. Participants underwent a 3-hour exposure to hypoxic conditions simulating an altitude of 4,000 meters above sea level (m.a.s.l.) in a hypobaric pressure chamber.
- Trial name
- NCT02849821
- Testing
- hypobaric pressure chamber, Sigmoidoscopy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Healthy
13C Trioctanoate Breath Test as a Measurement of Gastric Fat Volume Emptying
13C breath tests represent an attractive alternative in the measurement of gastric emptying (GE). Therefore these tests have been used in a variety of clinical settings such as in the assessment of gastroparesis, delayed GE in…
- Trial name
- 13CTriOBT (NCT02602158)
- Testing
- Octanoic acid (1-13C, 99%), TRIOCTANOIN (1,1,1-13C3, 99%)
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Immunosuppression, Skin Neoplasms
Sunbit UV Measuring Device to Track Sun Behavior
Sunbit is a new wearable UV dosimeter to measure solar radiation in real time. The purpose of this study is to track sun behavior of patients at high risk for skin cancer, to investigate the feasibility of this prototype in daily…
- Trial name
- NCT02221843
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University of Zurich
Skin Cancer, Infection Reactivation
Viral Reactivation and Skin Cancer
Several studies show that the incidence of skin cancer parallels the length and depth of immunosuppression. This study will analyze the correlation of viral reactivation and skin cancer in organ transplant recipients.
- Trial name
- NCT02395562
- Where
- Switzerland
- Volunteers
- 1,200 people
- Sponsor
- University of Zurich
Personality Features in Anorexia Nervosa
Motivation to Change, Coping, and Self-Esteem in Adolescent Anorexia Nervosa
By use of several questionaires, this study aimed at an investigation of the changes in motivation, symptoms, self-esteem and coping style in adolescent patients with anorexia nervosa..
- Trial name
- NCT02828956
- Volunteers
- 92 people
- Sponsor
- University of Zurich
Hypertension
Phosphate in Blood Pressure Regulation
High dietary phosphate intake in the general population is associated with a higher risk for developing kidney disease and cardiovascular disease with an increased overall mortality.
- Trial name
- Phos-RR (NCT02822131)
- Testing
- sodium phosphate, sevelamer, sodium bicarbonate, sodium chloride
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Spinal Cord Injuries
Effectiveness of Automated Locomotor Training in Patients With Acute Incomplete Spinal Cord Injury: A Multicenter Trial
The purpose of this study is to determine whether longer locomotor training results in a mor favorable outcome in patients with incomplete spinal cord injury.
- Trial name
- NCT01147185
- Testing
- Locomotor training using a robotic device
- Where
- 4 sites in Germany, Spain and 1 more
- Volunteers
- 21 people
- Sponsor
- University of Zurich
Elective Surgery Requiring Tracheal Intubation Using an Oral Tracheal Tube
Blind Intubation Through The Self-Pressurised Disposable Air-Q Laryngeal Intubation Mask: An International Multicentre Trial
The disposable Air-Q self-inflating laryngeal intubation mask (Air-Q, Mercury Medical, Clearwater, FL, USA) is an extra-glottic airway device which enables blind intubation with a tracheal tube.
- Trial name
- NCT01906060
- Testing
- Air-Q Intubation Laryngeal Mask
- Where
- 3 sites in Poland, Switzerland
- Volunteers
- 1,000 people
- Sponsor
- University of Zurich
Adenocarcinoma, Stomach Cancer
Prospective Evaluation of the Preoperative Lymph Node Staging in Patients With Cancer of the Esophagogastric Junction and Stomach
This prospective study includes patients with histologically proven cancer of the esophagogastric junction (Siewert Type II and III) and the stomach.
- Conditions
- Adenocarcinoma, Stomach Cancer, Cancer of Esophagogastric Junction
- Trial name
- NCT00800969
- Testing
- FDG-PET-CT
- Where
- Switzerland
- Sponsor
- University of Zurich
COPD
The Improving Care in Chronic Obstructive Lung Disease Study A Cluster Randomized Trial
Background The Swiss health ministry launched a national quality program "QualiCCare" in 2011 to improve healthcare for patients with COPD.
- Trial name
- CAROL (NCT01921556)
- Testing
- active comparator, QualiCCare education
- Where
- Switzerland
- Volunteers
- 216 people
- Sponsor
- University of Zurich
Aortic Aneurysm
Evaluation of Aortic Aneurysms With Focus on Wall Stress and Wall Rupture Risk
Retrospective study to evaluate the impact of computational wall stress analysis based on computed tomography (CT) of ruptured and not-ruptured aortic aneurysms as an additional predictor for rupture with dedicated software.
- Trial name
- NCT02800876
- Testing
- CT-acquisition
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Palliative Patients, Surrogate Decision Maker
Multiprofessional Advance Care Planning and Shared Decision Making for End of Life Care
Multiprofessional Advance Care Planning and shared decision making for end of live care for terminal patients and their relatives.
- Trial name
- MAPS (NCT01914848)
- Testing
- Advance Care Planning ACP, Control Group
- Where
- Switzerland
- Volunteers
- 115 people
- Sponsor
- University of Zurich
Laryngeal Contact Granuloma
Characterization of Laryngeal Contact Granulomas: Retrospective Analysis of Symptoms, Promotive Factors and Therapy
Retrospective analysis of data from patients with laryngeal contact granulomas in order to identify possible differences and/or similarities between the cases and in order to determine whether and which conclusions can be drawn…
- Trial name
- NCT01967693
- Testing
- Retrospective analysis of data
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- University of Zurich