Clinical trials: sponsored by University of Zurich
Immune Senescence
Influence of Persistent CMV-infection on Immune Senescence
Recent studies indicate that persistent viral infections particularly with Cytomegalovirus (CMV) might have a negative impact on immune senescence (i.e. immunocompetence of elderly individuals).
- Trial name
- NCT00461695
- Testing
- Vaccination against TBEV (FSME Immun CC)
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- University of Zurich
User Experience
Desktop Versus Mobile Data Collection in Clinical Trial
Paper-based data collection for prospective clinical trials is associated with a poor quality of data collection. This typically involves missing or wrong data entry or a low recruitment rate, mainly due to the cumbersome and…
- Trial name
- NCT01473238
- Testing
- Evaluation form
- Where
- 2 sites in Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cholelithiasis, Cholecystitis
Efficacy of Proficiency-based Versus Free Laparoscopic Training in Cholecystectomy on a Virtual Reality Simulator
Virtual reality devices are widely accepted tools to familiarize surgical novices with the principles of laparoscopy. Free Virtual reality training will be tested against basic training and efficacy assessed in a randomized…
- Conditions
- Cholelithiasis, Cholecystitis, Cholecystolithiasis
- Trial name
- NCT01615549
- Testing
- Laparsocopic cholecystectomy
- Where
- 2 sites in Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Appendicitis, Abdominal Pain
The Value of Pancreatic Stone Protein in Predicting Acute Appendicitis
PSP (Pancreatic Stone Protein) is a compound naturally produced mainly in the pancreas and the gut. There is evidence from experimental and clinical trials that the levels of PSP in the blood rise in the presence of inflammation…
- Conditions
- Appendicitis, Abdominal Pain, Abdominal Sepsis
- Trial name
- NCT01610193
- Testing
- Appendicectomy
- Where
- 2 sites in Switzerland
- Volunteers
- 245 people
- Sponsor
- University of Zurich
Physiological Effects of Vitamin D
Vitamin D3, Folic Acid and Fexofenadine in Healthy Volunteers
The study is conducted to assess the effect of a vitamin D3 supplementation on the activities of two intestinal transporters and on the pharmacokinetics of the transporter substrates folic acid and fexofenadine.
- Trial name
- NCT01856348
- Testing
- Vitamin D
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Erosion Protection
Impact of Milk on Erosion/Abrasion of Enamel and Dentin - an in Situ Study
This in situ study aims to investigate the protective potential of milk and fluoridated milk on erosive wear of enamel the protective potential of milk and fluoridated milk on erosive wear of dentin to compare to protective…
- Trial name
- NCT01566357
- Testing
- Toothpaste, Milk, Fluoridated Milk
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pulmonary Hypertension
Smoking: a Risk Factor for Pulmonary Arterial Hypertension?
Environmental factors may play a role in the genesis of pulmonary hypertension, especially in endothelial dysfunction. One widespread environmental factor associated with systemic endothelial dysfunction is cigarette smoke.
- Trial name
- DACH (NCT01484899)
- Where
- 9 sites in Austria, Germany and 1 more
- Volunteers
- 500 people
- Sponsor
- University of Zurich
Ankylosing Spondylitis
Effects of Cardiovascular Training in Individuals With Ankylosing Spondylitis
To test the effects of a cardiovascular training compared to attention control in a group of AS-patients participating in classic spinal mobility exercise groups (randomized controlled trial)
- Trial name
- NCT00913302
- Testing
- Cardiovascular Training
- Where
- Switzerland
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Healthy
Non-erythroid Effects of Erythropoietin on Cognitive Function and Exercise Capacity in Humans
The blood hormone Erythropoietin (Epo) is not only produced by the kidneys but also by the brain, especially under hypoxic conditions. It has been shown in animal studies and human studies that Epo has neuroprotective properties.
- Trial name
- NCT01889056
- Testing
- Erythropoietin (Epoetin beta)
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Open Angle Glaucoma,, Ocular Hypertension
IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients
To investigate the effect of patterned laser trabeculoplasty (PLT) compared to selective laser trabeculoplasty (SLT) on intraocular pressure (IOP) in treatment naiv patients suffering from open-angle glaucoma or ocular…
- Trial name
- NCT01886456
- Testing
- Laser trabeculoplasty
- Where
- Switzerland
- Volunteers
- 210 people
- Sponsor
- University of Zurich
Chronic Venous Insufficiency, Post-thrombotic Syndrome
Practicability of Gliding Aids for Medical Compression Stockings
Medical compression stockings are highly effective in the prevention, treatment, and secondary prevention of chronic venous insufficiency and of post-thrombotic syndrome.
- Trial name
- NCT01432795
- Testing
- Gliding aids for medical compression stockings
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Iron Deficiency Anemia
Intravenous Ferric Carboxymaltose (Ferinject®) With or Without Erythropoietin in Patients Undergoing Orthopaedic Surgery
Study Design: Single-centre, block randomised, blinded, controlled, phase IIIb, parallel group pilot study. Primary Objective: To evaluate the effect of the administration of ferric carboxymaltose (Ferinject®) with or without…
- Trial name
- NCT00706667
- Testing
- Ferinject ®
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University of Zurich
Overweight
Development of Bone Grafts Using Adipose Derived Stem Cells and Different Scaffolds
The repair of large osseous defects remains still unsolved. Aim of this study is to isolate and cultivate fat-derived progenitor cells and differentiation into osteoblasts.
- Trial name
- NCT01218945
- Testing
- Cell Culture
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- University of Zurich
Heart Valve Diseases
Use of Standardized Diagnostic Imaging Data for Image Fusion in the Hybrid Operating Room
Objectives: Goal of the study is to investigate the potential benefit that transcatheter interventions such as Transcatheter Aortic Valve Implantation (TAVI), MitraClip, Left Atrial Appendage Closure and catheter Ablation can…
- Trial name
- NCT01821651
- Testing
- HeartNavigator, EchoNav, Control-Group EN
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University of Zurich
Glioma Patients
Hypertension Monitoring in Glioma Patients Treated With Bevacizumab
Prospective casecontrol study in glioma patients undergoing treatment with bevacizumab (Avastin). At present there are no data on the correlation between occurrence of arterial hypertension and clinical outcome in patients with…
- Trial name
- NCT01046279
- Testing
- Bevacizumab
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Cochlear Implant Recipients
Differences in Music Perception Skills Between Child, Teen and Adult Cochlear Implant Recipients
Adult recipients of cochlear implants (CI) generally loose interest in listening to music. This may be due to the rather limited spectral resolution of CI.
- Trial name
- NCT01876472
- Testing
- Assessment of music perception skills
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Health Behavior
vibroX-training in Endurance Trained Men
In endurance sports competitions such as cycling, an athlete's capacity to sustain submaximum power (i.e. endurance capacity) strongly influences overall race performance.
- Trial name
- NCT01672281
- Testing
- vibrox- vs. resistance training
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Stroke, Upper Extremity Paresis
Functional Recovery in Stroke Patients With Task-Specific Robot-Aided Arm Therapy
The goal of this study is to determine whether task-oriented, robot-aided therapy is more effective than conventional physical and occupational therapy at promoting functional recovery of the affected arm in chronic hemiparetic…
- Trial name
- NCT00719433
- Testing
- robot therapy (ARMin), conventional therapy
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University of Zurich
Performance
Influence of Sodium Bicarbonate on Time-to-exhaustion at Critical Power in Endurance Athletes
During endurance exercise in the heavy and severe intensity domains, the rate at which metabolites that have been associated with the fatigue process (e.g. Pi, ADP, H, and extracellular K) accumulate increases.
- Trial name
- NCT01621074
- Testing
- Sodium bicarbonate
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Herpes Zoster
Prevention of Varicella Zoster Virus (VZV)-Reactivation in HIV-positive Individuals Enrolled in a Prospective Immunogenicity and Safety Trial of VZV Vaccine: PROVE-IT-Study
The goal is to demonstrate the immunogenicity and safety of Zostavax® in HIV positive individuals. Study participants are stratified into different patient groups according to their CD4 cell count, viral load and HIV Status.
- Trial name
- NCT01213810
- Testing
- Zostavax
- Sponsor
- University of Zurich
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