Clinical trials: sponsored by Uppsala University
Neuroendocrine Tumors, Quality of Life
HRQoL During PRRT in Patients With NETs
Neuroendocrine tumours (NETs) can arise in different locations in the body, and may give rise to hormonal symptoms, which may affect the patients' health-related quality of life (HRQoL).
- Conditions
- Neuroendocrine Tumors, Quality of Life, Peptide Receptor Radionuclide Therapy
- Trial name
- NCT05427032
- Volunteers
- 756 people
- Sponsor
- Uppsala University
COPD, Physical Activity
Intervention Study to Investigate Supplemental Oxygen in COPD
The purpose of this trial is to study the effects on exercise capacity, physical activity, inflammatory markers and quality of life of supplemental ambulatory oxygen, to be used during physical activity, in patients with COPD who…
- Conditions
- COPD, Physical Activity, Sedentary
- Trial name
- NCT01783808
- Testing
- Supplemental oxygen
- Where
- Sweden
- Volunteers
- 144 people
- Sponsor
- Uppsala University
Healthy
An Attempt at Translating Novelty-enhanced Extinction of Context Conditioning From Rodents to Humans
In rodents, novel exploration has been used to strengthen the consolidation of a variety of hippocampal-dependent learning tasks.
- Trial name
- NCT05150951
- Testing
- Novel Exploration, Threat conditioning, Extinction
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Respiratory Tract Infections, Respiratory Syncytial Virus Infections
Inflammatory Mediators Associated With Infection by Respiratory Syncytial Virus
Infection with human respiratory syncytial (RS) virus is the most common cause of hospital stay due to pediatric lower respiratory tract infection.
- Trial name
- IMAR (NCT03757429)
- Testing
- RS-virus infection
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- Uppsala University
Sepsis, ARDS, Human
Factors Associated With Decisions to Withhold or Withdraw Intensive Care
Medical and socioeconomic data are extracted from the Swedish Intensive Care Registry (SIR), the Swedish National Patient Registry and Statistics Sweden for all adult patients admitted to in Swedish intensive care units between…
- Conditions
- Sepsis, ARDS, Human, COVID-19
- Trial name
- NCT05394961
- Testing
- Treatment in an intensive care unit with a diagnosis of sepsis and/or ARDS and/or covid-19
- Where
- Sweden
- Volunteers
- 33,256 people
- Sponsor
- Uppsala University
Dihydropyrimidine Induced Gastrointestinal Toxicity in Colorectal Cancer
Role of Antisecretory Factor in Dihydropyrimidine Treatment of Colorectal Cancer
One debilitating, and sometimes even life-threatening, toxicity from dihydropyrimidines, e g 5-FU and capecitabine, is gastrointestinal mucositis resulting in, eg severe diarrhoea necessitating in-hospital care including periods…
- Trial name
- SALFLADMET (NCT05339230)
- Where
- Sweden
- Volunteers
- 73 people
- Sponsor
- Uppsala University Hospital
Back Problems or Pain, Foot Problems or Pain
Rehabilitation Coordinators in Orthopedic Care
REKO-O is a study that addressed women and men on sick leave in Uppsala County. Participants which are enrolled in orthopedic care clinic.
- Conditions
- Back Problems or Pain, Foot Problems or Pain, Shoulder Problems or Pain
- Trial name
- REKOO (NCT03944018)
- Testing
- Intervention with rehabilitation coordinator
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Uppsala University
Covid19
Long Term Outcome in ICU Treated COVID-19: Risk Factors for 1-year Mortality
Mortality within one year after intensive care unit (ICU) admission with Coronavirus disease 2019 (COVID-19) will be assessed. Risk and risk factors for one year mortality in ICU patients will be compared to patients admitted to…
- Trial name
- NCT05063747
- Testing
- No intervention.
- Where
- Sweden
- Volunteers
- 13,537 people
- Sponsor
- Uppsala University
Covid19
Long Term Outcome in ICU Treated COVID-19: New Chronic Diseases
Additional chronic diseases one year after intensive care unit (ICU) admission with Coronavirus disease 2019 (COVID-19) will be assessed in comparison to two control cohorts.
- Trial name
- NCT05075096
- Testing
- No intervention.
- Where
- Sweden
- Volunteers
- 60,000 people
- Sponsor
- Uppsala University
Pancreatic Neuroendocrine Tumor
Biomarker Study of Pancreatic Neuroendocrine Tumours
The biology of pancreatic neuroendocrine tumors can change during the disease course. This evolution of disease can manifest through increases in tumor proliferation rate, resistance to medical therapy and/or a change in tumor…
- Trial name
- NCT03741517
- Testing
- 18F-FDG-PET, 68Ga-DOTATOC-PET, Computed tomography
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University
Type 2 Diabetes
The Effect of Blood Flow Restriction Training on Glycemic Control Among Type 2 Diabetes Patients
Blood flow restriction training (BFRT) combined with resistance or aerobic exercise has been shown to improve the glucose uptake in humans.
- Trial name
- BLFT (NCT04946799)
- Testing
- Low-intensity training combined with blood flow restriction (LI-BFR), High-intensity aerobic exercise (HI), Low intensity exercise (LI)
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Uppsala University
Obesity
Double-blinded, 6 Months Study With Bydureon® or Placebo in Adolescents With Obesity to Explore Changes in BMI
Combat-JUDO (Combating Juvenile Diabetes and Obesity through normalization of beta-cell function) is part of a collaborative project funded by the Seventh Framework Programme of the European Commission aiming to develop…
- Trial name
- Combat-JUDO (NCT02794402)
- Testing
- Exenatide
- Where
- 2 sites in Austria, Sweden
- Volunteers
- 44 people
- Sponsor
- Uppsala University
Mechanical Ventilation Complication, Neurological Disorder
The Cerebral-Respiratory Interaction in Controlled Mechanically Ventilated Neurosurgical Patients. (The CeRes-CMV Study)
The impact of mechanical ventilation on intracranial perfusion is still not completely clarified. It is often assumed that raising airway pressure will invariably elevate the intracranial pressure, but this is not always the…
- Conditions
- Mechanical Ventilation Complication, Neurological Disorder, Lung Injury
- Trial name
- CeRes-CMV (NCT05363085)
- Testing
- Mechanically ventilated neurosurgical patients
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Mechanical Ventilation Complication, Neurological Complication
The Cerebral-Respiratory Interaction During Spontaneous Breathing Ventilation in Neurosurgical Patients (CeRes-SB)
Mechanical ventilation (MV) is a life-saving supportive therapy and one of the most common interventions implemented in intensive care.
- Conditions
- Mechanical Ventilation Complication, Neurological Complication, Respiratory Complication
- Trial name
- CeRes-SB (NCT05363098)
- Testing
- Mechanically ventilated neurosurgical patients
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Primary Aldosteronism Due to Aldosterone Producing Adenoma, Primary Aldosteronism Due to Nodular Hyperplasia
First-in-human Evaluation of [18F]CETO
Purpose of this clinical phase 1 trial was to determine if para-chloro-2-[18F]fluoroethyletomidate positron emission computed tomography ([18F]CETO-positron emission computed tomography(PET)/computed tomography(CT)) can be used…
- Conditions
- Primary Aldosteronism Due to Aldosterone Producing Adenoma, Primary Aldosteronism Due to Nodular Hyperplasia, Adrenal Cushing Syndrome, Non-Secretory Adrenal Adenoma
- Trial name
- NCT05361083
- Testing
- F18CETO
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Anal Cancer
Role of Antisecretory Factor in Curative Radiochemotherapy for Anal Carcinoma
Curative radiochemotherapy (RCT) for anal carcinoma (AC) is associated with considerable acute and long-term toxicity. The acute toxicity derives from the combined effects of radiation and chemotherapy and is dominated by…
- Trial name
- SALFLAC (NCT05351931)
- Volunteers
- 38 people
- Sponsor
- Uppsala University Hospital
Fibromyalgia, Respiratory Alkalosis and Metabolic Acidosis
Evaluation of Respiratory Function in Fibromyalgia
This study will evaluate respiratory function in people with fibromyalgia and whether or not breathing patterns in this patient group can be explained by stress, emotional or biomechanical variables.
- Conditions
- Fibromyalgia, Respiratory Alkalosis and Metabolic Acidosis, Chronic Hyperventilation
- Trial name
- NCT04098731
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Covid19, Myeloma Multiple
Impact of COVID-19 After Autologous Hematopoietic Stem Cell Transplantation in Sweden
This retrospective observational cohort study aims to describe the impact of COVID-19 in patients treated with autologous stem cell transplantation (ASCT) for malignant disease in terms of risk factors, morbidity, need for…
- Conditions
- Covid19, Myeloma Multiple, Malignant Lymphoma, Hematologic Neoplasms
- Trial name
- AutoCOVID-19 (NCT04760184)
- Testing
- Autologous stem cell transplantation
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Uppsala University
Chronic Pain
Psychological Flexibility in Chronic Pain Populations; an Observation- and Validation Study
Chronic pain in general is a substantial problem and is a source of a great deal of disability and suffering. It is known that processes like stigma and psychological flexibility (PF) play a significant role in these outcomes.
- Trial name
- NCT05050565
- Testing
- Experiences of stigma and psychological flexibility in chronic pain participants
- Where
- Sweden
- Volunteers
- 404 people
- Sponsor
- Uppsala University
Non-clinical Participants, Intrusive Memories
Understanding Reactions to Emotional Material in the Media During COVID-19 - Study 2
This second feasibility study aims to adapt a protocol usually run in the laboratory in the Psychology Department for healthy participants (including the trauma film paradigm (James et al., 2016) and a simple cognitive task…
- Trial name
- NCT05063825
- Testing
- Simple cognitive task intervention
- Where
- Sweden
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Uppsala University