Clinical trials: sponsored by Uppsala University
Insomnia
Implementation of Internet-based Cognitive Behaviour Therapy for Adolescents With Co-morbid Insomnia
Insomnia is a commonly reported comorbidity for adolescents with psychiatric conditions. It is well-known that insomnia can exacerbate the concurrent psychiatric symptom load.
- Trial name
- NCT03492905
- Testing
- Internet-based Cognitive Behaviour Therapy (iCBT)
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Uppsala University Hospital
Acute Kidney Injury, Anesthesia
The Effect of Propofol or Sevoflurane on Renal Function
This study investigates the role of the anesthetic agents propofol and sevoflurane on renal function in otherwise healthy patients undergoing basic back surgery.
- Trial name
- NCT03336801
- Testing
- Back Surgery, Propofol, Sevoflurane
- Where
- Sweden
- Volunteers
- 37 people
- Sponsor
- Uppsala University
Obesity, Morbid
Effect of Bariatric Surgery on Cognition, Genetics and Lifestyle
Obesity bariatric surgery patients usually lose more than 50% of their former obesity within a relatively short time (~ 2 years).
- Trial name
- NCT02085369
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Uppsala University
Depression, Depressive Symptoms
Treatment of Depressive Symptoms in Older Individuals in Isolation During Covid-19
This research study is designed to investigate the effects of a brief psychological intervention for improving depressed mood in older individuals (65 years and older) in isolation during the Coronavirus (COVID-19) pandemic.
- Trial name
- CoviDep (NCT04508868)
- Testing
- Brief Behavioral Activation with Mental Imagery, Minimal Attention Control Intervention
- Where
- Sweden
- Volunteers
- 41 people
- Sponsor
- Uppsala University
Anxiety Disorders, Post Traumatic Stress Syndrome
Auricular Acupuncture as an add-on Treatment for Symptoms of Anxiety
Mental illness is very common in todays' society, and it is the most common cause for sick leave in Sweden. Affective diseases, such as different states of anxiety and depression, are the two most common conditions of mental…
- Trial name
- NCT04654884
- Testing
- Auricular acupuncture (AA)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Cryotherapy Effect
Cryoprotection of Chemotherapy-induced Oral Mucositis After Autologous Stem Cell Transplantation, a Randomized Study
This study evaluates, among study patients with lymphoma or myeloma undergoing autologous SCT, whether cooling oral mucosa with a cooling device compared with ice cubes/crushed ice or ice pop succeeds in reducing the degree of…
- Trial name
- NCT03203733
- Testing
- Cooral™, cryotherapy
- Where
- 5 sites in Norway, Sweden
- Volunteers
- 182 people
- Sponsor
- Uppsala University
Malnutrition
Effects of Nutritional Supplementation and Dietary Advice in Elderly Patients After Hospital Discharge.
The purpose of this study is to evaluate the effects of nutritional therapy in elderly malnourished patients. The hypothesises are that nutritional supplementation and dietary advice alone or in combination affects mortality…
- Trial name
- NCT01057914
- Testing
- Nutritional supplementation with a liquid formula, Dietary advice, Combination of supplement and dietary advice
- Where
- 5 sites in Sweden
- Volunteers
- 671 people
- Sponsor
- Uppsala University
Type 1 Diabetes Mellitus
Mesenchymal Stem Cells to Intervene in the Development of Type 1 Diabetes: a Blinded Randomized Study
This project aims to evaluate the efficacy of autologous mesenchymal stem cell treatment to preserve insulin production and beta-cell mass in recently diagnosed patients with type 1 diabetes mellitus.
- Trial name
- NCT02057211
- Testing
- autologous mesenchymal stem cell transplantation
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Uppsala University Hospital
Renal Failure, Anesthesia
Renal Function During Pediatric Anesthesia
It is known that volatile anesthesia, such as sevoflurane, retain water and that this appears more pronounced in children. However, the mechanisms for this effect is unknown and it is not clear if the commonly used anesthetic…
- Trial name
- NCT02571426
- Testing
- Sevoflurane, propofol
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Circulating Tumor Cell, Peritoneal Metastases
Circulating Tumour Cells in Patients With Peritoneal Metastases
This study aims to evaluate the prognostic value of circulating tumour cells (CTC) in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy due to gastrointestinal cancers that have spread to the…
- Conditions
- Circulating Tumor Cell, Peritoneal Metastases, Hyperthermic Intraperitoneal Chemotherapy
- Trial name
- NCT04083547
- Testing
- iCellate
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Uppsala University
Oxidative Stress, Inflammation
Milk and Soured Milk (filmjölk) Intervention on Oxidative Stress and Inflammation
This study evaluates a high intake of milk compared with a high intake of soured milk (Swedish filmjölk) on markers of oxidative stress and inflammation in a randomized crossover intervention study.
- Trial name
- NCT03821116
- Testing
- Milk, Soured milk (filmjölk)
- Where
- Sweden
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Depression, Anxiety
Internet-based Cognitive Behavior Therapy After Myocardial Infarction
The overall aim and primary objective is to evaluate the effects on level of depression and anxiety of an Internet-based CBT-program in depressed and/or anxious patients after a myocardial infarction (MI).
- Conditions
- Depression, Anxiety, Myocardial Infarction
- Trial name
- U-CARE: Heart (NCT01504191)
- Testing
- Internet-based CBT
- Where
- 25 sites in Sweden
- Volunteers
- 239 people
- Sponsor
- Uppsala University
Long Term Sick Leave, Absent-mindedness
Joint Coordination to Facilitate the Transition From Sick Leave to Employment
GESAM is a randomized controlled intervention study that addressed women and men on long-term sick leave in Uppsala County. Participants which are on sick leave due to mental illness and/or pain and were expected to reach the…
- Trial name
- GESAM (NCT03348410)
- Testing
- Motivational interviewing
- Where
- Sweden
- Volunteers
- 193 people
- Sponsor
- Uppsala University
Pelvic Girdle Pain
Low Level Laser Therapy in Persistent Pelvic Girdle Pain
Persistent pregnancy-related pelvic girdle pain is common, 2-5% av all women given birth is suffering from disabling daily pain with high impact on quality of life.
- Trial name
- NCT02789735
- Testing
- Active laser therapy
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University
COVID-19, Critical Illness
COVID-19 in the Swedish ICU-cohort: Risk Factors of Critical Care Admission and Intensive Care Mortality
The Corona virus disease 2019 (COVID-19) pandemic is currently involving all parts of the world. Several risk factors for critical illness and death from the disease have been proposed.
- Trial name
- NCT04390074
- Testing
- COVID-19 and Intensive Care
- Where
- Sweden
- Volunteers
- 9,905 people
- Sponsor
- Uppsala University
Mental Disorder, Rehabilitation
Rehabilitation Coordinators in Specialist Psychiatry
REKO-A is a randomized controlled intervention study that addressed women and men on sick leave in Uppsala County. Participants which are on sick leave due to mental illness.
- Trial name
- NCT03729050
- Testing
- Rehabilitation Coordinator in Specialist Psychiatry
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Uppsala University
Chronic Pain, Depressive Symptoms
Internet-delivered Cognitive Behavioral Therapy for Patients With Chronic Pain and Psychiatric Distress
This study is a randomized controlled trial studying the efficacy of an iCBT treatment for patients with chronic pain and comorbid psychiatric distress.
- Conditions
- Chronic Pain, Depressive Symptoms, Anxiety, Stress, Psychological
- Trial name
- TIPPS (NCT03316846)
- Testing
- Internet-Delivered Cognitive Behavioral Therapy
- Where
- Sweden
- Volunteers
- 187 people
- Sponsor
- Uppsala University
Chronic Insomnia, Chronic Pain
Internet-based CBT for Insomnia in Chronic Pain
The main goal is to study the effect of therapist-guided internet-delivered cognitive behavioural therapy for insomni comorbid with chronic pain in a clinical sample.
- Trial name
- IBIS (NCT03075683)
- Testing
- Cognitive behavioural therapy, Applied relaxation
- Where
- Sweden
- Volunteers
- 85 people
- Sponsor
- Uppsala University
Peripheral Vascular Diseases, Heart Failure
Peripheral Artery Disease in Vastmanland
The main purposes of this study are: to describe the prevalence and degree of reduced left ventricular function and hypertrophy in patients with peripheral arterial disease in comparison to controls from the general population…
- Conditions
- Peripheral Vascular Diseases, Heart Failure, Ventricular Dysfunction
- Trial name
- PADVa (NCT01452165)
- Where
- Sweden
- Volunteers
- 457 people
- Sponsor
- Uppsala University
Schizophrenia, Depression
Magnetic Stimulation of the Brain in Schizophrenia or Depression
The primary objective is to evaluate if repetitive transcranial magnetic stimulation (rTMS) with theta burst frequency over dorsomedial prefrontal cortex (DMPFC) is an effective treatment for negative symptoms (anhedonia and…
- Conditions
- Schizophrenia, Depression, Anhedonia, Avolition
- Trial name
- MA-SCH-DEP (NCT02905604)
- Testing
- dmPFC iTBS
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University