Clinical trials: sponsored by Uppsala University
Irritable Bowel Syndrome, Constipation
Spinal Cord Stimulation for Pain Relief in Irritable Bowel Syndrome
To elucidate Spinal Cord Stimulation (SCS) as treatment for IBS. An SCS system with a 4-polar electrode at the T5-8 level is implanted.
- Conditions
- Irritable Bowel Syndrome, Constipation, Diarrhea, Pain
- Trial name
- NCT01726751
- Testing
- Spinal Cord Stimultion (SCS), Spinal cord nerve stimulation
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Uppsala University
Colorectal Neoplasms
Quantitative Immunochemical Fecal Occult Blood Test in Symptomatic Patients
The aim of this study is to compare the outcome of three (3) quantitative immunochemical faecal occult blood test in symptomatic patients.
- Trial name
- FIKA (NCT02491593)
- Testing
- fecal occult blood test
- Where
- Sweden
- Volunteers
- 242 people
- Sponsor
- Uppsala University
Oxygen Toxicity, Oxidative Stress
Optimized Oxygen Delivery During General Anesthesia in Newborn Infants
An open randomized control trial investigating the delivery of two levels of inspired oxygen to newborn infants during general anesthesia.
- Trial name
- ANOXneo (NCT02698020)
- Testing
- Room-air
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Uppsala University
Diabetes Mellitus
Complement Inhibitor Eculizumab in Clinical Islet Transplantation
This is a dual centre, single arm, exploratory study of the possibility to use eculizumab (Soliris) to prevent/reduce destruction of islets of Langerhans after portal infusion of the islets in patients with diabetics accepted for…
- Trial name
- ICC (NCT02727608)
- Testing
- Eculizumab
- Where
- Sweden
- Volunteers
- 3 people
- Sponsor
- Uppsala University
Diabetes Mellitus, Type 1, Diabetes Mellitus
Azithromycin Insulin Diet Intervention Trial in Type 1 Diabetes
Increasing evidences suggest that infections are important etiological factors for the development of Type 1 Diabetes (T1D). The overall hypothesis of the study is that the treatment of children, during the first year after…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Metabolic Disease, Glucose Metabolism Disorders
- Trial name
- AIDIT (NCT03682640)
- Testing
- Azithromycin Monohydrate, Insulin Lispro, Dietician support
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University
Cardiovascular Risk Factor, Lifestyle Risk Reduction
Implementation of a Structured Lifestyle Program in Primary Care. Changes in Lifestyle Habits and Cardiovascular Risk.
The aim of the present study is to describe and evaluate the effect of a structured lifestyle intervention program, focusing on lifestyle habits, in a primary care setting in patients with high cardiovascular risk.
- Conditions
- Cardiovascular Risk Factor, Lifestyle Risk Reduction, Primary Care
- Trial name
- NCT03681002
- Testing
- structured lifestyle program
- Volunteers
- 450 people
- Sponsor
- Uppsala University
Adhesive Small Bowel Obstruction
A Study of the Cost for Patients Operated for Adhesive Obstruction (SBO) During a Five-year Period
A cohort study of the cost for patients operated for adhesive small bowel obstruction (SBO) during a five-year period
- Trial name
- NCT03602352
- Volunteers
- 402 people
- Sponsor
- Uppsala University
Oro-cecal Transit Time
Rapid Orocecal Transit Time and Fermentation in IBS.
Orocecal transit time is studied in individuals with irritable bowel syndrome (IBS) of both the constipation-dominant, diarrhea-dominant, and mixed form using the lactulose hydrogen breath test for orocecal transit time through…
- Trial name
- RapidoIBS (NCT03141268)
- Testing
- Lactulose breath test
- Where
- Sweden
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Functional Gastrointestinal Disorders
GLP-1 Inhibits Prandial Antro-duodeno-jejunal Motility in Humans
The inhibitory effect of low dose GLP-1 is investigated on prandial motility of the stomach, duodenum and jejunum in vivo in humans.
- Trial name
- GLPMOT (NCT02731664)
- Testing
- GLP-1, Intravenous saline
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Irritable Bowel Syndrome
Transplantation of Anaerobic Cultured Human Intestinal Microbiota in Irritable Bowel Syndrome
Patients with irritable bowel syndrome (IBS) are treated with microbiota from a human intestinal anaerobic sample cultured for decades. Patients are recruited consecutively with symptoms of IBS and serve as their own controls.
- Trial name
- ACHIM2 (NCT02857257)
- Testing
- ACHIM
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Uppsala University
Pain
Behavioral Medicine Treatment for Adolescents in Pain
Recurrent pain, such as headache, stomach pain and musculoskeletal pain is common in children and adolescents. Children and adolescents are reported to have restrictions in daily life activities, social contacts, and school…
- Trial name
- NCT01381263
- Testing
- Behavioural medicine treatment, Standard treatment
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Uppsala University
Adhesive Small Bowel Obstruction
Surgery for Adhesive Small Bowel Obstruction in a Defined Population: a Cohort Study
A cohort study of patients operated for adhesive small bowel obstruction (SBO) during a five-year period
- Trial name
- NCT03534596
- Volunteers
- 402 people
- Sponsor
- Uppsala University
Acute Psychosis
Acceptance & Commitment Therapy for Psychotic Inpatients
The overarching aim of the research project is to investigate whether Acceptance \& Commitment Therapy (ACT) is an efficacious psychotherapeutic method of treatment for inpatients suffering from acute psychosis.
- Trial name
- NCT02458105
- Testing
- Acceptance & Commitment Therapy, Attention
- Where
- Sweden
- Sponsor
- Uppsala University
Rotator Cuff Injury
Rehabilitation After Rotator Cuff Repair
A new postoperative regimen with a new bandage technique after surgery results in a better shoulder function and quality of life after surgery - than traditional postoperative regimen with shoulder lock and abductor cushion.
- Trial name
- NCT02261701
- Testing
- Early mobilization, Post surgery shoulder lock
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Uppsala University
Intertrochanteric Fracture
PFN-A Augmentation for Intertrochanteric Femoral Fractures
This study evaluates the potential negative effect of cement augmentation in the femoral head on viability of the head. Half of the participants will have the standard intramedullary nail (PFN-A; Proximal Femoral Nail…
- Trial name
- NCT03000972
- Testing
- Cement augmentation, PFN-A Nail
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Uppsala University
Intellectual Disability, Adolescent Development
Prevention Among Young People With Intellectual Disability
This study aims to evaluate an intervention using the Toolkit "Children - what does it involve?" and the "Real-Care-Baby" (RCB) simulator among students with intellectual disability (ID), using a cluster randomized trial design…
- Conditions
- Intellectual Disability, Adolescent Development, Young Adult
- Trial name
- NCT03348124
- Testing
- "Children - what does it involve?"
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Uppsala University
Diverticulitis
Diagnostics in Diverticulitis (DIDit)
This study focuses on if low dose CT without intravenous contrast has a high enough specificity and sensitivity for acute diverticulitis that it can be used as the primary diagnostic method instead of a full dose CT with…
- Trial name
- NCT03443011
- Testing
- Low dose CT without intravenous contrast
- Where
- Sweden
- Volunteers
- 149 people
- Sponsor
- Uppsala University
Abdominal Aortic Aneurysm
The Efficacy of Ticagrelor on Abdominal Aortic Aneurysm (AAA) Expansion
Abdominal aortic aneurysm (AAA) is a major health problem and ruptured AAA is a common cause of death in Europe and North America.
- Trial name
- TicAAA (NCT02070653)
- Testing
- Ticagrelor
- Where
- Sweden
- Volunteers
- 145 people
- Sponsor
- Uppsala University
Serum Concentrations, Intoxication
Blood Serum Concentrations of Routine Drugs in Patients Treated in the Intensive Care Unit.
To follow up the result of a quality measurement based on the results of a new routine for drug analysis introduced during a period of time in the intensive care unit.
- Conditions
- Serum Concentrations, Intoxication, Post Mortem Concentrations
- Trial name
- INTOx (NCT02305004)
- Where
- Sweden
- Volunteers
- 359 people
- Sponsor
- Uppsala University
Fear of Childbirth, Pregnancy
Fear of Childbirth - Comparison of Two Treatments
Childbirth related fear is a public health issue strongly related to subsequent reproduction, a request for caesarean section and women's and children's health.
- Trial name
- NCT02306434
- Testing
- Therapy by iCBT, Standard care-counselling
- Where
- Sweden
- Volunteers
- 258 people
- Sponsor
- Uppsala University