Clinical trials: sponsored by Uppsala University
Muscle Weakness, Vitamin D Deficiency
Vitamin D and Physical Performance Before and After Intervention and Birth Outcome in Pregnant Somali and Swedish Women
Somali migrant women, often in veiled clothing, living in a town in mid Sweden on the 60:th parallel were observed to be weak and to have a waddling gate.
- Trial name
- NCT02922803
- Testing
- 1 combination tablet of Vitamin D3/calcium per day, 2 combination tablets of Vitamin D3/calcium per day
- Where
- Sweden
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Behavioral Problems
Motivation and Adherence to Psychotherapy Assignments
The aims of this study are to experimentally investigate and compare whether motivation variables can predict adherence to a prescribed assignment in face-to-face and online interventions using a psychotherapy analogue model.
- Trial name
- AIDAII (NCT02895308)
- Testing
- Online psychoeducation, Face-to-face psychoeducation
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Acute Ischemia of Lower Limb
Treatment of Acute Lower Limb Ischaemia in Sweden 1994-2014
Study of acute lower ischemia therapies based on data collected from the Swedish Vascular Surgery Registry between 1994 and 2014.
- Trial name
- NCT02835027
- Testing
- Open versus endovascular surgery
- Volunteers
- 16,287 people
- Sponsor
- Uppsala University Hospital
Stroke
Effect of Intensified Physical Activity for Patients With Stroke - a Combined Physical and Behavioural Approach
Chronic conditions such as stroke are associated with physical disability and an economic burden for the family and the society.
- Trial name
- NCT01161329
- Testing
- High-Intensity Functional Exercise Programmes (HIFE)
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Uppsala University
Methods to Measure Contrast Vision
A Comparative Study of Six Methods to Measure Human Contrast Vision
This study evaluates the relative performance of different methods to measure the human spectral contrast sensitivity function (CSF).
- Trial name
- NCT02767284
- Testing
- UCST-V1, UCST-V2, UCST-V3
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Meningitis
Pneumococci and Hib Vaccination After Neurotrauma or Neurosurgery
The purpose of this study is to determine wether skull trauma or neurosurgery affect the immune response to two vaccine types.
- Trial name
- NCT02806284
- Testing
- PPSV23, Act-HIB
- Volunteers
- 85 people
- Sponsor
- Uppsala University
Colles' Fracture
Short Versus Conventional Plaster Cast Fixation Time in Reduced Distal Radius Fractures
The purpose of this study is to compare the radiographic and clinical outcomes after short versus conventional plaster cast fixation time in reduced distal radius fractures.
- Trial name
- GitRa (NCT02798614)
- Testing
- 10-day cast
- Volunteers
- 109 people
- Sponsor
- Uppsala University Hospital
Central Nervous System Tumour, Arteriovenous Malformation
Proton Radiotherapy for Primary Central Nervous System Tumours in Adults
Open label, multi-centre prospective study. Adult patients with primary central nervous system tumours fulfilling the inclusion criteria according to the study protocol.
- Trial name
- PRO-CNS (NCT02797366)
- Testing
- Proton radiotherapy
- Where
- 6 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Uppsala University
Spinal Cord Injury, Urinary Tract Infection
Effect of Cranberry Capsules on Urinary Infection Rates in Spinal Cord Injured Patients During Post Acute Rehabilitation
The purpose of this study is to establish whether cranberry capsules reduce rates of urinary tract infections during initial rehabilitation immediately after spinal cord injury.
- Conditions
- Spinal Cord Injury, Urinary Tract Infection, Rehabilitation
- Trial name
- NCT01079169
- Testing
- Cranberry capsules
- Where
- Sweden
- Volunteers
- 3 people
- Sponsor
- Uppsala University
Behavior Therapy
Therapy Labs: To Improve Adherence in Internet Based Psychotherapy
This project aims to investigate factors that are important in affecting adherence in internet based Cognitive Behavior Therapy (CBT).
- Trial name
- NCT02535598
- Testing
- Normal presentation, Enhanced presentation, Normal support
- Where
- Sweden
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Female Circumcision, Female Genital Mutilation/Cutting
A Community-based Participatory Intervention to Change Attitudes Towards Female Circumcision Among Somali Immigrants in Sweden
Female circumcision (FC) causes both immediate and long-term health consequences. In general, the more severe type of FC, the worse health consequences can be seen.
- Trial name
- NCT02335697
- Testing
- Attitude change towards female circumcision, No intervention
- Where
- Sweden
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Gastroparesis, Hip Fracture
Gastric Emptying in Elderly With Hip Fracture
The gastric emptying of 400 ml 12.6% carbohydrate rich drink is investigated in elderly women, age 75-100, with acute hip fracture.
- Conditions
- Gastroparesis, Hip Fracture, Mild Insufficient Nutrition
- Trial name
- GASEMPHIP (NCT02753010)
- Testing
- Gastric emptying of carbohydrate-rich beverage
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Pressure Ulcer
Reduced Pressure for Less Pressure Ulcers
Pressure ulcers (PU) cause pain and discomfort to affected patients, as well as considerable costs for society. The present study will evaluate the effect of the Continuous Bedside Pressure Mapping (CBPM)- system on PU prevalence…
- Trial name
- NCT02474979
- Testing
- CBPM-system, Control
- Where
- Sweden
- Volunteers
- 190 people
- Sponsor
- Uppsala University
Malignant Melanoma
Phase I/IIa AdCD40L Immunogene Therapy for Malignant Melanoma and Other Solid Tumors
In this phase I/II trial, immunostimulatory gene therapy (AdCD40L) will be investigated. In Part 1 patients with melanoma will receive AdCD40L as mono therapy.
- Trial name
- NCT01455259
- Testing
- AdCD40L
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Dyspnea
Trial of Caffeine to Alleviate Dyspnea Related to Ticagrelor
Ticagrelor treatment is associated with increased rates of dyspnea, where previous studies have implied a possible role of adenosine.
- Trial name
- TROCADERO (NCT02311088)
- Testing
- Caffeine
- Where
- 9 sites in Sweden
- Volunteers
- 26 people
- Sponsor
- Uppsala University
Hernia, Inguinal
Randomized Study of Open Mesh Repair in Local Anesthesia Versus Cost-optimized Laparoscopic Repair for Inguinal Hernia
The purpose of this study is to compare the frequency of long-term post operative pain after an open mesh repair ad modum Lichtenstein performed in local anaesthesia to that after an totally extraperitoneal laparoscopic repair…
- Trial name
- NCT01020058
- Testing
- Mesh repair for primary inguinal hernia
- Where
- 2 sites in Sweden
- Volunteers
- 384 people
- Sponsor
- Uppsala University Hospital
Lumbar Spinal Stenosis
Swedish Spinal Stenosis Study
A national randomized multicentre trial (RCT) where decompression is compared with decompression with simultaneous fusion in 245 patients with spinal stenosis on one or two adjacent lumbar levels with or without degenerative…
- Trial name
- SSSS (NCT01994512)
- Testing
- Decompression without fusion, Decompression with fusion
- Volunteers
- 245 people
- Sponsor
- Uppsala University
Musculoskeletal Neck Pain, Musculoskeletal Shoulder Pain
Activity and Life-role Targeted Pain Rehabilitation in Primary Health Care
The primary goal of the Swedish national rehabilitation plan on pain is to reduce disability and facilitate return-to-work. However, there is a lack of treatment strategies that effectively target and affect return-to-work and…
- Trial name
- NCT01447953
- Testing
- Activity targeted pain rehabilitation, Treatment as usual
- Where
- Sweden
- Volunteers
- 65 people
- Sponsor
- Uppsala University
Breast Cancer, Stress
Stress Management in Breast Cancer Patients
The purpose of this study within Caring sciences is to identify women with breast cancer who have stress symptoms and to offer these women appropriate care to reduce stress and increase well-being. This will be achieved by 1.
- Trial name
- NCT01555645
- Testing
- Stress management, in two steps
- Where
- 3 sites in Sweden
- Volunteers
- 466 people
- Sponsor
- Uppsala University
Cancer of Liver, Cancer of Pancreas
Effects of Dexmedetomidine During IRE Procedures for Solid Tumours
The purpose of the study is to evaluate effects of dexmedetomidine on anaesthesia during IRE procedures for solid tumours
- Trial name
- NCT02044224
- Testing
- Dexmedetomidine
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University Hospital