Clinical trials: sponsored by VA Office of Research and Development
Heart Failure
Targeted Intervention to Improve Medication Adherence in Cognitively Impaired Patients With HF (TARGET)
Trialing an automated medication dispensing device (AMDD) to improve medication adherence in patients with heart failure.
- Trial name
- TARGET (NCT01602731)
- Testing
- Automated Medication Dispensing Device
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- VA Office of Research and Development
Nicotine Use Disorder, Nicotine Dependence
Baclofen Effects on Smoking Urge and Withdrawal
The purpose of this study is to determine whether baclofen is effective in reducing smoking urge, withdrawal, and reinforcement in moderate to heavy cigarette smokers.
- Conditions
- Nicotine Use Disorder, Nicotine Dependence, Smoking, Tobacco Use Disorder
- Trial name
- NCT00257894
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea Syndromes
Using Telemedicine to Improve Veteran Sleep Apnea Care
Obstructive sleep apnea (OSA) is highly prevalent in the Veteran population given the risk factors of male gender, being overweight, and increasing age.
- Trial name
- NCT01259440
- Testing
- Video Teleconferencing Care, Usual Care
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Disease, Stroke
A Personalized Dashboard to Educate Veterans at Risk of Stroke
Personalized risk communication methods have been used to educate patients that are at a high risk of developing cardiovascular disease.
- Trial name
- NCT01133171
- Testing
- Nurse Alone, Dashboard Plus Nurse
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- VA Office of Research and Development
Knee Osteoarthritis
Shoe Modification and Knee Osteoarthritis
This trial will assess the ability of shoe inserts to relieve pain and disability in people with knee osteoarthritis (OA) in the inner (medial) aspect of the knee.
- Trial name
- NCT00105365
- Testing
- Shoe insert, walking shoes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
PTSD
Divalproex Sodium in the Treatment of PTSD (Post-Traumatic Stress Disorder)
The purposes of this study are: To study the efficacy of divalproex in the treatment of PTSD; To study the plasma GABA (gamma aminobutyric acid) levels before and after treatment with divalproex in PTSD.
- Trial name
- NCT00108576
- Testing
- Divalproex
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- VA Office of Research and Development
Coronary Heart Disease
The VA HDL Intervention Trial (HIT): Secondary Prevention of Coronary Heart Disease in Men With Low HDL-Cholesterol and Desirable LDL-Cholesterol
This was a double-blind randomized trial comparing 1200 mg per day of gemfibrozil with placebo in 2531 men with coronary heart disease, an HDL-C of 40mg/dl or less, an LDL-C of 140 mg/dl or less, and triglycerides of 300mg/dl or…
- Trial name
- HIT (NCT00283335)
- Testing
- gemfibrozil
- Where
- United States
- Volunteers
- 2,531 people
- Sponsor
- VA Office of Research and Development
Cataract
Comparison of AC and PC Lenses After Vitreous Loss During ECCE
Objective: The standard definition of failure in cataract surgery is best corrected visual acuity of less than 20/40 at one year.
- Trial name
- NCT00453011
- Testing
- posterior chamber intraocular lens, anterior chamber intraocular lens
- Volunteers
- 1,202 people
- Sponsor
- VA Office of Research and Development
Heart Failure
Veterans Affairs Lowering Readmission in Heart Failure
Heart failure (HF) greatly increases mortality and lowers quality of life (QOL). HF is the most common indication for readmission in older adults and the most frequent reason for 30-day readmission.
- Trial name
- VALOR in HF (NCT01144182)
- Testing
- Comprehensive quality improvement program (QIP)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Esophagitis, Inflammation
Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule
The purpose of this research is to study the level of acid exposure above the gastroesophageal junction and the distal esophagus in patients with reflux symptoms using a capsule type acid measurement system.
- Conditions
- Esophagitis, Inflammation, Gastritis, Abdominal Pain
- Trial name
- NCT00579410
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development