Clinical trials: sponsored by Vanderbilt University Medical Center
Video Laryngoscopic Device Usage in Novice Users
Comparison Study of the McGrath MAC Video Laryngoscope With the King Vision
In this study, the investigators compare the effectiveness of two relatively new video laryngoscopes, McGrath MAC (Covidien, Dublin Ireland) and the King Vision (King Systems, Noblesville, IN), by practitioners experienced in…
- Trial name
- NCT02316769
- Testing
- King Vision video laryngoscope, McGrath MAC video laryngoscope
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Obesity, Overweight
Weight Loss Study for Patients With Obesity Due to Craniopharyngioma or Other Brain Tumor
The purpose of this study is to determine whether exenatide can cause weight loss in patients with a history of craniopharyngioma or other brain lesion.
- Conditions
- Obesity, Overweight, Craniopharyngioma
- Trial name
- NCT01484873
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University Medical Center
Identify Normal MII-pH Parameters
Assessing Normal Multichannel Intraluminal Impedance (MII)-pH Parameters for Today's Population
The normal values of a Multichannel Intraluminal Impedance (MII)-pH study can vary between ages, gender, race and different values of body mass index (BMI).
- Trial name
- NCT01566383
- Testing
- 24-hr pH monitoring
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
ACE Inhibitor-associated Angioedema
Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema
Individuals with heart disease or high blood pressure are often prescribed angiotensin converting enzyme (ACE) inhibitors to treat their disease.
- Trial name
- NCT01574248
- Testing
- icatibant
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Vanderbilt University Medical Center
Hypertension
Treatment of Resistant Hypertension by Prevention of T-Cell Co-Stimulation
The purpose of this study is to test whether abatacept, a drug approved by the Food and Drug Administration to treat rheumatoid arthritis, may help blood pressure medications to work better.
- Trial name
- NCT02232880
- Testing
- Abatacept
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Vanderbilt University Medical Center
Obesity
The Role of the Omentum in the Treatment of Morbid Obesity
The purpose of this research is to determine some of the reasons that blood sugar and insulin levels improve after bariatric surgery but before weight loss begins, as well as why people respond differently to weight loss surgery.
- Trial name
- NCT00212160
- Testing
- omentectomy
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Obesity, Insulin Resistance
Ghrelin and Insulin Resistance
Ghrelin, a hormone produced in the stomach that stimulates hunger and food intake, declines immediately after weight loss surgery. Some studies suggest that ghrelin may worsen an individual's ability to respond to insulin.
- Conditions
- Obesity, Insulin Resistance, Normal Weight,Healthy Controls
- Trial name
- NCT00884494
- Testing
- Ghrelin infusion to assess effects on insulin sensitivity
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Obesity, Hypertension
Pathophysiology of Cardiometabolic Risk Factors in African Americans
The overall goal of this proposal is to determine the autonomic and nitric oxide contribution in the pathogenesis of hypertension and insulin resistance in obese African American women.
- Trial name
- NCT01122407
- Testing
- L-NMMA, Trimethaphan
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Postural Tachycardia Syndrome
Assessment of Vascular Endothelial Function in Postural Tachycardia Syndrome
The purpose of this study is to see if people with Postural Tachycardia Syndrome (POTS) have different levels of certain chemicals in their blood than people who don't have POTS.
- Trial name
- NCT01308099
- Testing
- Blood Pressure and Blood Flow
- Where
- 2 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Orthostatic Hypotension, Pure Autonomic Failure
Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
The autonomic or automatic nervous system helps control blood pressure. Diseases of the autonomic nervous system may result in a drop in blood pressure on standing in many cases leading to fainting.
- Conditions
- Orthostatic Hypotension, Pure Autonomic Failure, Multiple System Atrophy, Parkinson's Disease
- Trial name
- 6103 (NCT01316666)
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Vanderbilt University Medical Center
Metabolic Syndrome, Obesity
Nutrition and Exercise Study to Understand Metabolic Syndrome
The purpose of this study is to measure the metabolic and behavioral effects of a 12-week yoga program coupled to health education (HED) compared to HED alone.
- Conditions
- Metabolic Syndrome, Obesity, Insulin Resistance
- Trial name
- NCT02899910
- Testing
- Health education, Yoga
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Breathing, Mind-body Practices
Study to Measure Relaxation From Different Types of Focused Breathing Exercises
Mind-body practices, such as yoga, ta'i chi, mindfulness and biofeedback, commonly use slow breathing techniques to induce physiological and mental relaxation.
- Conditions
- Breathing, Mind-body Practices, Yoga, Meditation
- Trial name
- NCT02226744
- Testing
- Focused Breathing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Obesity
Metabolic and Cardiovascular Impact of CD36 Deficiency in African Americans
CD36, a protein that facilitates tissue uptake of fat, as a common link between blood fat concentrations and metabolic disease states such as diabetes mellitus.
- Trial name
- NCT02126735
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center