Clinical trials: sponsored by Virginia Commonwealth University
Chronic Low Back Pain, Fear of Pain
The VIGOR Study - Virtual Immersive Gaming to Optimize Recovery in Low Back Pain
This study will measure the effects of interactive, whole-body video games on movement behavior in people with chronic low back pain.
- Conditions
- Chronic Low Back Pain, Fear of Pain, Fear of Injury
- Trial name
- VIGOR (NCT03463824)
- Testing
- Experimental Group 1, Experimental Group 2
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Virginia Commonwealth University
Tobacco Use
The Abuse Liability of a Novel Heated Tobacco Product (IQOS) and Its Feasibility as a Menthol Cigarette Substitute
This project examines the influence of flavor availability on switching to an MRTP known as IQOS, part of the Heated Tobacco Product (HTP) class, among menthol smokers using clinical lab and naturalistic evaluations of abuse…
- Trial name
- NCT05499377
- Testing
- Tobacco product administration and assessment
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Functional Gastrointestinal Disorders
Transcutaneous Electric Nerve Stimulation (TENS) for Vagal Modulation
This study is to determine if the auricular microstimulator produces the expected increase in HRV.
- Trial name
- NCT05987813
- Testing
- TENS Unit
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Autism Spectrum Disorder
Effect of a 9-Month Internship Intervention for Military Dependents With ASD
The aims of the project are: 1. VCU will modify the Project SEARCH Plus ASD Model to meet the needs of military dependents with ASD. 2.
- Trial name
- NCT04001790
- Testing
- Project Search plus ASD Supports
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Drug Interaction, Analgesics
Drug-drug Interaction Study of Lemborexant as an Adjunctive Treatment for Buprenorphine/Naloxone for Opioid Use Disorder
The purpose of this research study is to test the safety, tolerability, drug interactions with buprenorphine-naloxone, and effectiveness lemborexant when used to treat Opioid Use Disorder.
- Conditions
- Drug Interaction, Analgesics, Opioid Use Disorder
- Trial name
- NCT04818086
- Testing
- Lemborexant, Buprenorphine-naloxone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Virginia Commonwealth University
Myocardial Fibrosis, Myocardial Injury
Myocardial Perfusion and Fibrosis in Cancer Survivors
This is a cross-sectional pilot study. The investigators seek to obtain early information pertaining to the relationship between measurements of myocardial perfusion reserve and myocardial fibrosis after receipt of…
- Conditions
- Myocardial Fibrosis, Myocardial Injury, Chemotherapeutic Toxicity
- Trial name
- NCT03191461
- Testing
- Adenosine stress test MRI
- Where
- 2 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Breast Cancer
Improving Uptake of Genetic Cancer Risk Assessment in African American Women- Video
Genetic counseling and testing (GCT) provides invaluable information for women who are at-risk of hereditary breast and/or ovarian cancer (HBOC). Black women underutilize GCT compared to White women.
- Trial name
- NCT04476654
- Testing
- YouTube Video Arm
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Virginia Commonwealth University
Caries,Dental, Apical Periodontitis
Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - General
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine…
- Trial name
- NCT04104789
- Testing
- Kovanaze Nasal Spray, Articaine Injection
- Sponsor
- Virginia Commonwealth University
Overweight and Obesity, Pediatric Obesity
Evaluating the Feasibility of a Stepped-care Approach to Treating Adolescents With Binge and Loss of Control Eating
There are limited evidence-based treatments for adolescents with binge eating and fewer specifically targeting adolescents with both binge eating and overweight/obesity.
- Conditions
- Overweight and Obesity, Pediatric Obesity, Eating, Binge
- Trial name
- NCT03404713
- Testing
- Pathways to Health, Be4U
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Virginia Commonwealth University
Mental Stress, Emotional Stress
Trauma Informed Care for Newly Resettled Refugees
The main purpose of this study is to evaluate early-phase interventions for refugee wellness promotion and build evidence for dissemination of the intervention model and curricula through refugee resettlement programs, local and…
- Trial name
- NCT03288935
- Testing
- TICM, TICO
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Schizophrenia
HDAC Inhibitor Augmentation to Clozapine
The main goal of this pilot study is to test the extent to which adjunctive treatment with the histone deacetylase (HDAC) inhibitor vorinostat improves brain plasticity and cognition in a pilot placebo-controlled trial in…
- Trial name
- NCT03263533
- Testing
- Vorinostat Oral Capsule Group 1, Vorinostat Oral Capsule Group 2
- Sponsor
- Virginia Commonwealth University
Surgical Blood Loss, Burns
Measurement of Blood Volume Loss During Burn Surgery
Burn surgery is associated with significant reductions in hematocrit. However, it is unclear whether these reductions are the result of hemodilution from non-red cell containing intraoperative transfusions or from loss of red…
- Trial name
- NCT03340116
- Testing
- Burn surgery, Measurement of RBC volume, plasma volume, and total blood volume using Daxor BVA-100
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Parkinson Disease
Vibrational Therapy to Improve Gait and Balance in Parkinson's Disease
The purpose of this research study is to determine optimum dose of vibration delivered by an experimental device called PDVibe2 required to treat freezing of gait in persons with Parkinson's disease (PD).
- Trial name
- NCT03872115
- Testing
- PDVibe2
- Sponsor
- Virginia Commonwealth University
Stress, Mood
The Effect of a Therapy Dog Activity on Employees' Stress, Mood, and Job Satisfaction and Commitment
The goal of the current study is to determine if participating in a therapy dog activity is associated with changes in perceived stress, mood, and job satisfaction and commitment.
- Conditions
- Stress, Mood, Job Satisfaction
- Trial name
- NCT03849144
- Testing
- Therapy dog activity, Low impact exercise
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Renal Insufficiency, Chronic
The Effects of Passive Heat Therapy in Patients With Chronic Kidney Disease
The objective of this proposal is to investigate the acute effects of whole-body passive heat therapy using far-infrared technology on vascular function, exercise capacity, and renal function in CKD patients.
- Trial name
- NCT05924919
- Testing
- Whole-body Passive Heat Therapy (HT), Thermoneutral Control (CON)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University
Pediatric Obesity
Exploring the Familial Reach of Adolescent Obesity Treatment
An observational study ancillary to the randomized clinical trial (RCT) TEENS+ (R01HD095910), a family-based lifestyle intervention, for adolescents with obesity, to determine: 1) if family-wide changes to the shared home…
- Trial name
- NCT05780970
- Testing
- No intervention
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Virginia Commonwealth University
Tobacco Use
Effects of an Oral Nicotine Product in Smokeless Tobacco Users
The purpose of this research study is to find out how three different nicotine pouches and participant's own brand of smokeless tobacco affect blood nicotine levels and how participants feel.
- Trial name
- NCT05280769
- Testing
- oral nicotine pouch - 2 mg, oral nicotine pouch - 4 mg, oral nicotine pouch - 8 mg
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Pain, Procedural
The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort
The purpose of this study is to compare patient responses during and after surgery when local anesthetic is used for dental treatment under general anesthesia (GA) and when it is not used.
- Trial name
- NCT04500158
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Virginia Commonwealth University
Smoking
Checking Smoking Status as a Routine Vital Sign: A Cluster-Randomized Trial of Its Effect on Cessation Counseling
The purpose of this study is to determine if checking smoking status as a routine vital sign increases the delivery rate of cessation counseling to adult smokers in primary care practices.
- Trial name
- NCT00245323
- Testing
- Smoking status as a routine vital sign
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Virginia Commonwealth University
Autism
Effect of Parenting With Positive Interven on Comm Inclusion for Military Connected and Dependents With Autism
The purpose of this research study is to find out if a training program for parents with military dependent or connected children with autism (ASD) who have challenging behavior will help those children and their families…
- Trial name
- NCT05580432
- Testing
- Parenting with Positive Behavior Interventions
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Virginia Commonwealth University