Clinical trials: sponsored by Virginia Commonwealth University
Gastroesophageal Reflux Disease, Non Erosive Reflux Disease
Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD)
The purpose of this study is to find out if people who have non-erosive reflux disease (NERD) have changes the investigators can see with a microscope (called confocal endomicroscopy) that is used during endoscopy (a camera scope…
- Conditions
- Gastroesophageal Reflux Disease, Non Erosive Reflux Disease, Dyspepsia
- Trial name
- CE_NERD (NCT02039869)
- Testing
- Confocal endomicroscopy, Proton pump inhibitor, Sucralfate
- Where
- 3 sites in United States
- Sponsor
- Virginia Commonwealth University
Breast Cancer
Epigenetics and Psychoneurologic Symptoms in Women With Breast Cancer
This study examines the relationship among epigenetic alterations and the development and persistence of psychoneurologic symptoms (cognitive dysfunction, depressive symptoms, anxiety, fatigue, sleep disturbance, and pain) in…
- Trial name
- NCT01411943
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Virginia Commonwealth University
Ventilator Associated Pneumonia
Strategies to Prevent Pneumonia (SToP Pneumonia)
This study tests whether special oral care provided by nurses to critically ill patients who are on a breathing machine (mechanical ventilator) can help to reduce the build-up of dental plaque on the teeth and reduce the risk of…
- Trial name
- NCT00234598
- Testing
- Toothbrushing only, Chlorhexidine only, Toothbrushing and Chlorhexidine
- Where
- United States
- Volunteers
- 547 people
- Sponsor
- Virginia Commonwealth University
Substance Use Disorder
Computerized Screening, Brief Intervention, and Referral to Treatment in Primary Care
This is a randomized, controlled clinical trial to evaluate the effect of a computerized screening, assessment, and brief intervention on substance use in patients recruited from a primary care clinic.
- Trial name
- SBIRT (NCT01003834)
- Testing
- Computerized brief intervention, Computerized health screening, Computerized assessment
- Where
- United States
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Anxiety Disorder, Breast Cancer
Cranial Stimulation for Chemotherapy Symptoms in Breast Cancer
RATIONALE: Cranial microcurrent electrical stimulation (CES) is mild electrical current received through electrodes placed on the earlobes. CES may lessen symptoms in women with breast cancer receiving chemotherapy.
- Conditions
- Anxiety Disorder, Breast Cancer, Depression, Fatigue
- Trial name
- NCT00902330
- Testing
- energy-based therapy
- Volunteers
- 161 people
- Sponsor
- Virginia Commonwealth University
Childhood Brain Tumor, Childhood Hodgkin Lymphoma
Dietary and Exercise Interventions in Preventing Cardiovascular Disease in Younger Survivors of Leukemia, Lymphoma, or Brain Tumors
This clinical trial studies dietary and exercise interventions in preventing cardiovascular disease in younger survivors of childhood cancer.
- Conditions
- Childhood Brain Tumor, Childhood Hodgkin Lymphoma, Childhood Non-Hodgkin Lymphoma, Malignant Childhood Neoplasm
- Trial name
- NCT02000986
- Testing
- Specimen Collection/Risk Factor Assessment -> Diet/Exercise -> Chemotherapy
- Sponsor
- Virginia Commonwealth University
Pneumonia
A Peri-intubation Oral Intervention to Reduce Oral Flora and VAP
The purpose of this study is determine if a single, early dose of chlorhexidine applied within 12 hours after endotracheal tube insertion will reduce the bacteria in the oral cavity and the incidence of pneumonia in trauma…
- Trial name
- NCT00248300
- Testing
- Chlorhexidine
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Virginia Commonwealth University
Nausea, Vomiting
Randomized Trial of the Effectiveness of Topical "ABH Gel" vs. Placebo in Cancer Patients With Nausea
This randomized clinical trial studies ABH (lorazepam, diphenhydramine hydrochloride, and haloperidol) gel in patients with nausea. ABH gel, when absorbed into the skin, may be an effective treatment for nausea and vomiting.
- Trial name
- NCT01556932
- Testing
- ABH gel
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Virginia Commonwealth University
Overweight and Obesity
Motivational Interviewing in NOURISH for Parents of Overweight Children
The purpose of this study is to investigate if a brief, motivational interviewing intervention (NOURISH+MI) can improve retention and treatment adherence for parents enrolled in an intervention for their child's overweight…
- Trial name
- NOURISH+MI (NCT01912989)
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Virginia Commonwealth University
Lung Cancer
Prone Patient Positioning in Reducing Tumor Motion and Improving Breathing Reproduction in Patients With Lung Cancer Undergoing Radiation Therapy
This clinical trial studies prone patient positioning in reducing tumor motion and improving breathing reproduction in patients with lung cancer undergoing radiation therapy.
- Trial name
- NCT01851161
- Testing
- computed tomography, 4-dimensional computed tomography, radiation therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Virginia Commonwealth University
Flail Chest
Flail Chest - Rib Fixation Study
The purpose of this study is to determine whether operative fixation of unilateral flail chest provides greater benefit than non-operative treatment.
- Trial name
- NCT01147471
- Testing
- operative rib fixation, operative rib fixation surgery
- Where
- 7 sites in United States
- Volunteers
- 24 people
- Sponsor
- Virginia Commonwealth University
Metabolic Syndrome, Nonalcoholic Fatty Liver Disease
Prediction of Severity of Liver Disease by a 13C Octanoate Breath Test (OBT)
The purpose of the study is to demonstrate that the ¹³C-Octanoate Breath Test (OBT) can be used as an aid, in conjunction with other clinical information and medical history, for evaluating disease severity and detecting NASH…
- Trial name
- NCT01244503
- Testing
- Sodium Octanoate Breath Test
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- Virginia Commonwealth University
Leukemia, Not Otherwise Specified, Malignant Neoplasm
Efficacy of a Patient Education Video
Patients in the intervention arm will view the 23-minute video depicting the Hematopoietic stem cell transplantation (HSCT) experience.
- Trial name
- NCT02114827
- Testing
- Video, FAQ Sheet
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Virginia Commonwealth University
Epithelial Cancer
Randomized RT +/- Lapatinib for Advanced Solid Tumor Cancer Patients Receiving Radiation Therapy for Metastatic Disease
Lapatinib will prevent radiation-induced increase in Transforming Growth Factor alpha (TGFα), an important growth factor in cancer cell recovery after ionizing irradiation.
- Trial name
- NCT01427322
- Testing
- Lapatinib, Radiation therapy
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Virginia Commonwealth University
Cancer
Developing an Online Clinical Trial Specific Question Prompt List
The investigators will leverage e-technologies to provide an online version of the Question Prompt LIst (QPL-CT), that patients access via available iPads, enabling both the real-time prioritizing of patient questions as well as…
- Trial name
- NCT02030379
- Testing
- QPL-CT
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Virginia Commonwealth University
Atrial Fibrillation, Left Atrial Appendage Closure
Atrial Appendage Closure Prospective Observational Study
The purpose of this research is to monitor how well patients do after surgery for treatment of left atrial appendage (LAA).
- Trial name
- LARIAT (NCT02309268)
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Lung Cancer, Breast Cancer
Neural Stem Cell Preserving Brain Radiation Therapy & Stereotactic Radiosurgery in Patients With 1-6 Brain Metastases
For patients with 1-6 intraparenchymal brain metastases from various primary histologies (except for melanoma), stereotactic radiosurgery (administered upfront or concurrently) or complete surgical resection with neural stem cell…
- Conditions
- Lung Cancer, Breast Cancer, Prostate Cancer
- Trial name
- NCT00581113
- Testing
- Radiotherapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Virginia Commonwealth University
Health Behaviors, Obesity
Goal Setting for Health Behavior and Psychosocial Issues in Primary Care
The purpose of this delayed cluster randomized intervention trial is to evaluate primary care strategies to increase goal setting, shared decision-making and evidence-based support and counseling for health behaviors and…
- Conditions
- Health Behaviors, Obesity, Substance Abuse, Anxiety
- Trial name
- MOHR (NCT01825746)
- Testing
- Implementation of the MOHR assessment in primary care workflow
- Where
- 8 sites in United States
- Volunteers
- 3,591 people
- Sponsor
- Virginia Commonwealth University
Binge Eating/Loss of Control Eating
An Integrative Intervention for Loss of Control Eating Among Adolescent Girls
This study aims to develop a manualized and culturally sensitive intervention for adolescent girls targeting binge and loss of control (LOC) eating.
- Trial name
- NCT01395355
- Testing
- Linking Individuals Being Emotionally Real (LIBER8), Weight Management Control
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Virginia Commonwealth University
Adenocarcinoma of the Lung, Large Cell Lung Cancer
Phase I IGART Study Using Active Breathing Control and Simultaneous Boost for Patients With NSCLC
This phase I trial studies the side effects and best dose of image-guided adaptive radiation therapy using active breathing control when given together with chemotherapy and simultaneous integrated boost in treating patients with…
- Conditions
- Adenocarcinoma of the Lung, Large Cell Lung Cancer, Squamous Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer
- Trial name
- NCT02059967
- Testing
- Paclitaxel, image-guided adaptive radiation therapy, carboplatin
- Sponsor
- Virginia Commonwealth University