Clinical trials: sponsored by Virginia Commonwealth University
Overweight
Barriers to Effective Weight Loss in Overweight Adolescents
The current study aims to investigate the impact of a comprehensive, team-based, family-centered, lifestyle modification program on body weight, metabolic abnormalities, fitness measures, and self-esteem in overweight adolescents…
- Trial name
- TEENS (NCT00562263)
- Testing
- Lifestyle modification
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Obesity
Barriers to Treatment in Obese Adolescents
The purpose of this study is to identify significant racial and ethnical differences in risk factors for development of obesity and weight loss in adolescents in Central Virginia
- Trial name
- NCT00167830
- Testing
- Motivational Interviewing, Strength and Cardiovascular Conditioning, Food selection and portion control
- Where
- United States
- Volunteers
- 292 people
- Sponsor
- Virginia Commonwealth University
Minimal Hepatic Encephalopathy
Probiotic Lactobacillus GG (LGG) in Patients With Minimal Hepatic Encephalopathy
This research proposes to find whether the probiotic lactobacillus GG is safe and well tolerated in patients with minimal hepatic encephalopathy. We also want to get insight into the mechanisms of action of LGG.
- Trial name
- NCT00992290
- Testing
- Lactobacillus GG
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Virginia Commonwealth University
Lung Cancer
Implantation of Markers for the Radiotherapy of Lung Cancer Patients
This clinical trial studies imaging markers in planning radiation therapy in patients with lung cancer. Implanting markers in the tumor that can be seen using imaging procedures during radiation therapy may allow x-rays to be…
- Trial name
- NCT00856427
- Testing
- radiation therapy treatment planning/simulation, implanted fiducial-based imaging
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Virginia Commonwealth University
Mild Traumatic Brain Injury, Post-Concussive Syndrome
Hyperbaric Oxygen Therapy (HBO2T) for Post-Concussive Symptoms (PSC) After Mild Traumatic Brain Injury (mTBI)
The goal of this research is to serve as a demonstration project to determine the tolerability of individuals with persistent post-concussive symptoms from combat-related mild TBI (traumatic brain injury), identify dose-finding…
- Trial name
- HBOT (NCT01220713)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Virginia Commonwealth University
Cancer-related Problem/Condition, Neurotoxicity
Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients With Cancer
RATIONALE: Electrical stimulation pain therapy may help relieve chronic pain and numbness caused by chemotherapy. PURPOSE: This pilot trial studies electrical stimulation pain therapy in treating chronic pain and numbness caused…
- Conditions
- Cancer-related Problem/Condition, Neurotoxicity, Pain, Peripheral Neuropathy
- Trial name
- NCT01196442
- Testing
- electrical stimulation pain therapy, questionnaire administration
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Virginia Commonwealth University
Cardiovascular Diseases, Heart Diseases
Longitudinal Cardiac Outcomes and Body Composition
To relate cardiac structure and blood pressure (BP) elevation in adults to childhood BP and body size and composition.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00081692
- Volunteers
- 715 people
- Sponsor
- Virginia Commonwealth University
Traumatic Brain Injury, Brain Injury, Chronic
Evaluation of an Intervention Model for Family Crisis and Support
To learn more about how a family treatment program helps people after brain injury. Specifically, do families feel better and function better after going through the program, and do patients feel better and function better after…
- Trial name
- NCT00205530
- Testing
- Brain Injury Family Intervention (BIFI)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Virginia Commonwealth University
Traumatic Brain Injury, Acquired Brain Injury
Brain Injury Inpatient Educational Intervention for Families and Caregivers
The Brain Injury Inpatient Guide for Families and Caregivers (BIIG-FACS) is a comprehensive intervention to meet the needs of family members and significant others of patients who are undergoing acute, inpatient brain injury…
- Trial name
- BIIG-FACS (NCT01062243)
- Testing
- Brain Injury Education
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Virginia Commonwealth University
Breast Cancer, Radiation Toxicity
Lovastatin in Reducing Side Effects After Radiation Therapy in Women With Breast Cancer
RATIONALE: Drugs, such as lovastatin, may protect normal cells from the side effects of radiation therapy. PURPOSE: This phase II trial is studying how well lovastatin works in reducing side effects after radiation therapy in…
- Trial name
- NCT00902668
- Testing
- lovastatin, questionnaire administration, adjuvant therapy
- Volunteers
- 3 people
- Sponsor
- Virginia Commonwealth University
Healthy
Assessment of Inspiratory Profiles Through Airflow Resistances Designed to Mimic Inhalers
It is hypothesized that different inhalation profiles (inhalation flow rate versus time curves) result from different forms of patient training.
- Trial name
- NCT01410877
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Atrial Fibrillation
A Multicenter Data Registry for Outcomes From Surgical Treatment of Atrial Arrhythmias
Minimally invasive surgical treatment of atrial fibrillation is safe and effective at controlling atrial fibrillation. The fundamental goal of STAR Outcomes registry is to improve the understanding of the efficacy of surgical…
- Trial name
- STAR (NCT00747838)
- Testing
- Minimally Invasive Maze Procedure
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Virginia Commonwealth University
Cardiometabolic Risk, Cardiovascular Disease
Reduce Cardiovascular Risk in Women Through Tai Chi Intervention
Tai chi intervention may lead to relaxation and could potentially reduce the risk of cardiovascular disease. This project entails a comprehensive and innovative approach for understanding, measuring, and potentially reducing…
- Trial name
- NCT01467544
- Testing
- Tai Chi class
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Virginia Commonwealth University
Chronic Pancreatitis
A Prospective Study of Natural History of Pancreatitis
To prospectively define the natural history and the clinical, laboratory and histomorphometric features of chronic pancreatitis (CP) of varying etiology.
- Trial name
- NCT00685087
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Virginia Commonwealth University
Staphylococcus Aureus
Antimicrobial Drug Use and Resistant Staphylococcus Aureus
The purpose of this investigation is to study the relationships between antimicrobial stewardship program efforts, antimicrobial drug use, and infection control efforts to the incidence rates of hospital acquired infections with…
- Trial name
- NCT01075451
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Virginia Commonwealth University
Breast Cancer
Individualized Risk-Based Education in Promoting Breast Cancer Screening in Healthy Women
RATIONALE: Education, based on a patient's risk factors, may help promote breast cancer screening in healthy women. PURPOSE: This randomized clinical trial is studying individualized risk-based education to see how well it…
- Trial name
- NCT00416975
- Testing
- counseling intervention, educational intervention, evaluation of cancer risk factors
- Volunteers
- 899 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Prostate Cancer
Radiation Therapy Followed by Surgery in High-Risk, Localized Carcinoma of the Prostate
The purpose of the study is to assess the safety of four different doses of radiation therapy followed by to surgery to remove prostate tumor.
- Trial name
- NCT00691977
- Testing
- Radiation Therapy followed by prostatectomy
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Pulmonary Procedures
Registry for Patients Undergoing Pulmonary Procedures
The purpose of this research study is to examine the safety, tolerability, and effectiveness of currently available pulmonary procedures when used to diagnose or treat different diseases.
- Trial name
- NCT01397292
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Virginia Commonwealth University
HIV Infections, Substance Use
Reducing HIV: Safer Sex Skill Building in Pregnant Drug Abusing Women
This study will examine safer sex skills building (SSB), a targeted behavioral HIV prevention and risk reduction group intervention in two samples of pregnant drug abusing women.
- Trial name
- NCT00619320
- Testing
- Safer Sex Skills Building (SSB)
- Where
- 2 sites in United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Sedation, Mechanical Ventilation
Sedation and Psychopharmacology in Critical Care
Certain methods of sedation increase the duration of respiratory failure. Two strategies, a nursing- implemented sedation algorithm and daily interruption of sedatives, decrease length of mechanical ventilation compared to…
- Conditions
- Sedation, Mechanical Ventilation, Depression, Post-traumatic Stress Disorder
- Trial name
- NCT00205517
- Testing
- Daily interruption of sedation versus sedation algorithm
- Volunteers
- 75 people
- Sponsor
- Virginia Commonwealth University