Clinical trials: sponsored by Virginia Commonwealth University
Delirium
Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium
The use of weighted blankets to avert or alleviate Delirium in Adult ICU patients.
- Trial name
- NCT06161480
- Testing
- Weighted Blanket
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Glioma, Mixed, Mild Neurocognitive Disorder
C-SMART: Cognitive Strategies, Mindfulness, and Rehabilitation Therapy for Patients With Primary Brain Tumors
The goal of Phase Ib Trial is to determine the feasibility and acceptability of telehealth C-SMART for patients with primary brain tumor and mild neurocognitive deficits (N=18) and their caregivers (N=14) A subset (n=3) of…
- Conditions
- Glioma, Mixed, Mild Neurocognitive Disorder, Brain Tumor
- Trial name
- C-SMART (NCT05984667)
- Testing
- C-SMART
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Virginia Commonwealth University
Lived Experiences, Strengths, and Community Assets of Black Girls
Lived Experiences of Black Girls in Richmond
This study is to understand the quality of life of Black Girls in Richmond, Virginia, which includes generating a report about the status of Black girls in Richmond.
- Trial name
- NCT05858281
- Testing
- Survey, Interviews, Focus group
- Where
- United States
- Volunteers
- 339 people
- Sponsor
- Virginia Commonwealth University
Electronic Cigarettes
Determination of Liquid Flavor and Nicotine Form Outcomes
The purpose of this research study is to find out how different types of electronic cigarette/vape e-liquids with differing sweetness and forms of nicotine affect blood nicotine levels, use behavior (how people puff), and how…
- Trial name
- NCT05587504
- Testing
- E-cigarette with sweetness type 1 and pronation level 1, E-cigarette with sweetness type 1 and pronation level 2, E-cigarette with sweetness type 2 and pronation level 1
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Electronic Cigarette Use
Assessing Electronic Cigarette Nicotine Flux
The purpose of this study is to determine differences in nicotine delivery, use behavior, carbon monoxide delivery, subjective effects, and physiological effects, when cigarette smokers use an electronic cigarette with constant…
- Trial name
- NCT04378907
- Testing
- Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 6 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 15 mg/ml nicotine concentration
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Violence
Preventing Retaliatory Gun Violence in Violently Injured Adults
The purpose of this research study is to find out if a hospital-based violence intervention (Bridging the Gap) is effective for reducing violence.
- Trial name
- NCT04813185
- Testing
- Bridging the Gap
- Where
- United States
- Volunteers
- 616 people
- Sponsor
- Virginia Commonwealth University
Violence in Adolescence
Preventing Firearm Violence in Youth: A Hospital-based Prevention Strategy
The goal of the study is to understand if hospital-based violence interventions are effective for reducing youth violence among violently injured youth.
- Trial name
- NCT05078164
- Testing
- Bridging the Gap (BTG)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Virginia Commonwealth University
Castration-resistant Prostate Cancer
GZ17-6.02 in Advanced CRPC After Progression on Anti-Androgen Therapy
The purpose of this clinical trial is to determine if GZ17-6.02 delays progression of castration-resistant prostate cancer.
- Trial name
- NCT06636123
- Testing
- Investigational Agent Administration
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Commonwealth University
Diffuse Large B-cell Lymphoma, DLBCL - Diffuse Large B Cell Lymphoma
Zanubrutinib in Patients With DLBCL and MYD88 or NOTCH1 Mutation or CD5+
This study is a single-arm, open label, non-randomized, phase 2 trial of zanubrutinib in patients with diffuse large B-cell lymphoma (DLBCL) who have an MYD88 L265P mutation, a CD79B mutation, a NOTCH1 truncation, or who are CD5+…
- Trial name
- NCT06846463
- Testing
- Zanubrutinib
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Virginia Commonwealth University
Liver Transplant
Targeting Trimethylamine N-Oxide for Cardiovascular Health In Liver Transplant Recipients
Despite medical and surgical advances, long-term survival in liver transplant (LT) recipients is compromised by an increased risk of cardiovascular disease (CVD) after transplant, the mechanisms of which are still not fully…
- Trial name
- NCT06043531
- Testing
- Experimental: EVOO
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Virginia Commonwealth University
Electronic Cigarette Use
The Impact of Oral Ethanol and Vaped Ethanol on the Evaluation of Impairment
The purpose of this research study is to determine if ethanol-containing e-cigarettes impact ethanol breath, blood or oral fluid tests, field sobriety tests, or other tests of sobriety.
- Trial name
- NCT04522973
- Testing
- Beverage with ethanol and E-cigarette liquid with ethanol, Beverage with ethanol and E-cigarette liquid without ethanol, Beverage without ethanol and E-cigarette liquid with ethanol
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Alcohol Abuse
Genetic and Neural Factors in Alcohol-Related Cognition
This study examines the genetic factors that impact cognitive processes and behavior after alcohol consumption. Participation in this project will contribute to a better understanding of cognitive factors that influence alcohol…
- Trial name
- NCT03725345
- Testing
- MRI Scanner
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Obesity, Pediatric
Redesigning Pediatric Primary Care Obesity Treatment: Virtual House Calls
This study examines a redesign of pediatric primary care overweight/obesity treatment, augmenting typical in-person visits with: (1) direct-to-patient video telehealth to tailor counseling advice to families, (2) that leverages…
- Trial name
- NCT06078774
- Testing
- Virtual Health Coach
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University
Pediatric Obesity
Parent Involvement in Adolescent Obesity Treatment
A randomized control trial to compare the efficacy of two distinct parent treatments on weight loss maintenance for adolescents with obesity participating in a lifestyle intervention including nutrition education, exercise and…
- Trial name
- TEENS+ (NCT03851796)
- Testing
- TEENS+Parents as Coaches, TEENS+Parent Weight Loss
- Where
- United States
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Anxiety
Exploring Virtual Reality in Clinical Care - Impacts on Patient Distress, Parental Anxiety and Nurse Satisfaction
Prior experience with virtual reality (VR) in clinical care has demonstrated its potential to reduce patient anxiety and distress, particularly in pediatric settings.
- Trial name
- NCT07280910
- Testing
- Virtual Reality, Survey Responses/Parent Caregivers, Survey Responses/Nurses
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Virginia Commonwealth University
Stenosis Trachea
Cryospray Therapy for Benign Airway Stenosis
This is a clinical evaluation to assess the effectiveness of cryospray therapy used in addition to current standard of care endoscopic therapies in preventing short term recurrent airway stenosis with a multicentric outcome…
- Trial name
- CRYOSTASIS (NCT06085209)
- Testing
- The truFreeze Spray Cryotherapy, Ballon dilation, Radial Incision
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Virginia Commonwealth University
Dietary Intervention, Produce Prescription
Promoting Nutrition Security and Chronic Disease Management Through a Produce Prescription Program
The goal of this study is to assess the feasibility to implement a prescription produce program (PPP) over 12-months within a community-based health and wellness program.
- Conditions
- Dietary Intervention, Produce Prescription, Chronic Disease Management, Social Needs Screening
- Trial name
- NCT07117201
- Testing
- Culturally Tailored Cooking Classes, Prescription Produce Plan
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Commonwealth University
Obesity, Morbid
Bariatric Surgery Registry
Periodic analyses of our extensive database with regards to different surgical procedures for severe obesity and different obesity co-morbidities will be of benefit to our severely obese patients as well as to others world-wide.
- Trial name
- NCT01055054
- Where
- United States
- Volunteers
- 8,000 people
- Sponsor
- Virginia Commonwealth University
Breast Cancer
ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy
The purpose of this study is to compare any good and bad effects of giving radiation treatment for breast cancer in 3 treatments over about 2 days.
- Trial name
- ASHBY (NCT06185205)
- Testing
- Accelerated partial breast irradiation
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Virginia Commonwealth University
Autism
Improving Access to Community-Based Occupations Via a Rideshare Training Program
Community mobility is critical for living independently and engaging in one's community. It is especially important for people in their early adult years, as this is often a time of transition to employment and living…
- Trial name
- NCT06323850
- Testing
- Intervention Phase, Virtual Training Sessions, Ride-Along Training Sessions
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Virginia Commonwealth University