Clinical trials: sponsored by Virginia Commonwealth University
Intellectual Disability, Developmental Disability
Impact of Competency-Based Training and Technical Assistance Employment Outcomes of Individuals With ID/DD
Currently, there are no national pre-requisites for training to become or to be hired as an ES (Employment Specialist). Staff providing employment services have a broad range of educational and training backgrounds.
- Trial name
- NCT06586827
- Testing
- VCU-RRTC Online Course, Zoom Technical Assistance Sessions (6 total)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Virginia Commonwealth University
Pregnancy Related
Bringing Education Through Technology, Empathic Listening, and Research
The purpose of this study is to test a new educational technology-based program and brochure as a supplement to prenatal education from providers.
- Trial name
- BETTER (NCT05214118)
- Testing
- technology-based program
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Virginia Commonwealth University
Cystic Fibrosis
Non-pulmonary Contributors of Exercise Intolerance in Patients With Cystic Fibrosis
The purpose of this research study is to examine if the use of antioxidant supplements impacts exercise intolerance in people with CF.
- Trial name
- NCT04166396
- Testing
- Resveratrol, NR
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Multiple Chronic Conditions, Health Behavior
Enhanced Care Planning for Patients With Multiple Chronic Conditions
Patients with multiple chronic conditions (MCC) have a range of needs that extend beyond traditional medical care, including behavioral, mental health, and social needs.
- Conditions
- Multiple Chronic Conditions, Health Behavior, Mental Health, Social Determinants of Health
- Trial name
- NCT03885401
- Testing
- Enhanced care planning
- Where
- United States
- Volunteers
- 457 people
- Sponsor
- Virginia Commonwealth University
E-Cig Use
Understanding the Impact of Cartridge-Based Electronic Cigarettes and Generated Aerosols on Cardiopulmonary Health
Over the last decade, e-cigarettes have become increasingly popular, due to their promotion as a healthy alternative to traditional tobacco cigarettes.
- Trial name
- NCT05199480
- Testing
- Tobacco flavored liquid type 1, Tobacco flavored liquid type 2
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Performance at Work
Mindfulness in the OR
The purpose of this research study is to understand the effect of a short mindfulness video on self perceived performance in the OR.
- Trial name
- NCT04515667
- Testing
- Mindfulness, Video
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Cancer Survivors, Informal Caregivers
EW and Self-Guided PST in Cancer Survivors and Caregivers
To assess the feasibility and acceptability of expressive writing + problem solving therapy (EW+PST) among cancer survivors and informal caregivers
- Trial name
- NCT06282471
- Testing
- Expressive Writing and Problem-Solving Therapy (EW+PST)
- Sponsor
- Virginia Commonwealth University
Urinary Frequency/Urgency
Development of Novel Cystometrics for Overactive Bladder
Urinary urgency is the key symptom of overactive bladder (OAB). A critical barrier in understanding OAB is the lack of a method to separate urgency that derives directly from bladder filling or what we term "tension sensor…
- Trial name
- NCT02060214
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Alcohol Abuse, Alcohol Use Disorder
Integration of Neurofunctional Phenotyping Into Investigation of CBT4CBT for AUD
Alcohol use and misuse are prevalent in the United States. Alcohol use disorder (AUD) is the most common substance use disorder.
- Trial name
- NCT06190236
- Testing
- Stand-alone web-based cognitive behavioral therapy (CBT4CBT) for alcohol use disorder
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Virginia Commonwealth University
Hospitalized Children
The Role of Therapy Dogs in Reducing Depression, Anxiety, and Loneliness Among Hospitalized Children
The purpose of this research study is to test whether an animal-assisted intervention (AAI) is better than conversation with another person or treatment as usual for improving mood, anxiety, loneliness, quality of life, and…
- Trial name
- NCT05551156
- Testing
- Animal-assisted interaction, Conversational interaction
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Virginia Commonwealth University
Cancer Metastatic to Brain, Brain Metastases, Adult
Managing Distress in Malignant Brain Cancer
To identify potential adaptations of the managing cancer and living meaningfully (CALM) intervention that will be required for service members, Veterans, their beneficiaries, and civilian cancer metastasis to the brain (bMET)…
- Trial name
- NCT05087095
- Testing
- CALM Intervention
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Virginia Commonwealth University
Traumatic Brain Injury
Intervention to Promote Survivor Resilience and Adjustment: Efficacy and Sustainability
The aims of this traumatic brain injury (TBI) study are: 1. to evaluate the short and long-term efficacy of two structured outpatient intervention programs, Resilience and Adjustment Intervention (RAI) vs.
- Trial name
- NCT03421964
- Testing
- Resilience/Adjustment Counseling, Resilience/Adjustment Counseling with Booster Sessions
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Virginia Commonwealth University
Congenital Myotonic Dystrophy
Trial Readiness and Endpoint Assessment in Congenital Myotonic Dystrophy
Congenital Myotonic Dystrophy (CDM) is a multi-systemic, dominantly inherited disorder caused by a trinucleotide repeat expansion (CTGn) in the DMPK gene.
- Trial name
- TREAT-CDM (NCT03059264)
- Testing
- Natural history
- Where
- 3 sites in United States, Canada and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Bariatric Surgery Candidate, Post-operative Pain
Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients
Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within liposomes, which break down in soft tissue over…
- Trial name
- NCT06077214
- Testing
- Treatment with liposomal bupivacaine, Treatment with standard bupivacaine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Virginia Commonwealth University
Chronic Obstructive Pulmonary Disease
Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD)
Cardiovascular health is a critical problem in patients with chronic obstructive pulmonary disease (COPD). Existing literature suggests oxidative stress from the mitochondria c driving some of the poor health outcomes in COPD.
- Trial name
- NCT05605548
- Testing
- MitoQ
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Virginia Commonwealth University
Pulpitis
A Clinical Trial Comparing FS With ZOE and Non-eugenol Based Materials in Primary Teeth Pulpotomies
Internal resorption in the most common cause of failure in FS pulpotomies in primary molars. This has been attributed to the release of free eugenol from the zinc and eugenol mixture of the base material over the pulp tissue.
- Trial name
- NCT05557812
- Testing
- non-eugenol based ZOE base material with Ferric Sulfate in primary molar pulpotomies, eugenol based zinc oxide and Ferric Sulfate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Dental Caries, Tooth Decay
Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar Teeth
The purpose of this research study is to test the effectiveness of two different crowns/caps on teeth for restoration of primary molar teeth. The two different materials of crowns are resin polymer and stainless steel crowns.
- Trial name
- NCT06354634
- Testing
- Resin polymer (NuSmile Bioflx) crown, Stainless steel crown
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Virginia Commonwealth University
Dental Caries, Tooth Decay
Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves
The purpose of this research study is to test the effectiveness of two different crowns/caps on teeth for restoration of primary anterior teeth.
- Trial name
- NCT06354647
- Testing
- Zirconia-based primary anterior crowns with retention grooves, Zirconia-based primary anterior crowns without retention grooves
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interstitial Cystitis: Examination of the Central Autonomic Network
This proposal aims to move the science of chronic pelvic pain (CPP) from simple associations towards an investigation of cause and effect relationships.
- Trial name
- ICECAN (NCT03008382)
- Testing
- Metoprolol Tartrate Oral Tablet, No intervention- observational sub-study
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Electronic Cigarette Use
Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study)
This study aims to better understand how e-cigarettes (ECIG) nicotine flux impacts several behavioral economic measures of abuse liability.
- Trial name
- NCT04332926
- Testing
- Tobacco product administration and assessment, own brand cigarettes, Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University