Clinical trials: sponsored by Yale University
Nicotine Dependence
Targeted Interventions for Weight-Concerned Smokers
Weight gain after quitting smoking is an important barrier to treatment for many smokers. This study will test a drug called naltrexone with weight-concerned smokers to investigate whether or not this drug both improves smoking…
- Trial name
- NCT00105482
- Testing
- Naltrexone, Transdermal nicotine replacement, Behavioral counseling
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Yale University
Hepatitis C, Opiate Dependence
Effective Treatment of Hepatitis C in Substance Users
We hypothesize that integrating Hepatitis C into methadone and buprenorphine treatment will improve Hepatitis C outcomes as well as drug treatment outcomes in patients who are addicted to opiates.
- Trial name
- NCT00633243
- Testing
- Modified Directly Observed Therapy (mDOT), Self-Administered Therapy (SAT)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Yale University
Glaucoma
Effect of Age on Latanoprost 0.005% in Patients With Glaucoma
Latanoprost is a commonly used treatment for glaucoma. Because of its mechanism of action, it is plausible that the age of a patient using the medication may affect its efficacy and time of onset.
- Trial name
- NCT00224289
- Testing
- Latanoprost 0.005%
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV Infection, HIV Infections
Buprenorphine/Raltegravir Pharmacokinetic Interaction Study
The main purpose of this protocol is to study the effect of an HIV medication known as Raltegravir on Buprenorphine in people who have been receiving the same dose of Buprenorphine for at least 3 weeks before study entry.
- Trial name
- NCT00858962
- Testing
- Raltegravir
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV Infections
Pharmacokinetic Interactions Between Buprenorphine and Kaletra (Lopinavir/Ritonavir)
The main purpose of this protocol is to study the effect of an HIV medication, Kaletra (lopinavir/ritonavir), on buprenorphine in non-HIV infected people who have been receiving the same dose of buprenorphine for at least 3…
- Trial name
- NCT00571961
- Testing
- Kaletra (lopinavir/ritonavir), buprenorphine, Clinical evaluations/Blood draws
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Yale University
Basal Cell Carcinoma, Squamous Cell Carcinoma
Absorbable Suture Versus Tissue Glue to Repair Defects Following Mohs Surgery
The purpose of the study is to look at which nonpermanent superficial closure method, cyanoacrylate tissue glue or fast absorbing gut suture, leads to a better cosmetic and functional outcome in repairs of facial wounds after…
- Trial name
- NCT01298167
- Testing
- Cyanoacrylate tissue glue versus Fast absorbing gut
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Yale University
Cocaine Dependence, Substance-induced Sleep Disorder
Modafinil, Sleep, and Cognition in Cocaine Dependence
Subjects participating in this protocol will participate in three phases: 1) pre-admission, 2) inpatient admission, and 3) follow-up.
- Conditions
- Cocaine Dependence, Substance-induced Sleep Disorder, Substance-induced Cognitive Disorder
- Trial name
- NCT00582491
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Smoking
The Effect of Cycloserine on Smoking Behavior in Nicotine Dependent Smokers
A total of 20 subjects will participate in this four week, between groups, double-blind, placebo controlled study. Subjects will participate in two experimental sessions separated by approximately one week.
- Trial name
- NCT00633256
- Testing
- Cycloserine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University