Clinical trials: sponsored by Zhujiang Hospital
Chronic Graft-versus-host-disease, Leukemia Relapse
A Optimal Anti-Thymoglobuline (ATG) Dose Decrease cGVHD But Not Increase Leukemia Relapse for Haplo-HSCT
In this study, a randomized, prospective, multicenter, open cohort study was conducted to investigate patients with acute leukemia (14～60-year-old) with different ATG doses (10 mg / kg and 12.5 mg / kg ) in fludarabine, busulfan…
- Trial name
- NCT03190733
- Testing
- ATG
- Volunteers
- 192 people
- Sponsor
- Zhujiang Hospital
Diagnoses Disease, Glioma of Brain
The Efficacy of APT Magnetic Resonance Imaging in Predicting the Efficacy of Bevacizumab in Recurrent Malignant Gliomas
Targeted therapy with bevacizumab is the main method to prolong the progression-free survival of patients with recurrent malignant gliomas in recent years.
- Trial name
- APT (NCT03180697)
- Testing
- APT MR Imaging
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhujiang Hospital
Infantile Hemangioma, Capillary Hemangioma
A Prospective Study on the Incidence and Related Risk Factors of Infantile Hemangioma in China
Infant hemangioma(IH) is the most common benign vascular tumor of infancy with the estimated incidence varies 1% to 12%.However, in China, the incidence of infant hemangioma and related epidemiological data remains unclear.
- Conditions
- Infantile Hemangioma, Capillary Hemangioma, Capillary Hemangiomas, Hemangioma, Capillary Infantile
- Trial name
- IH (NCT03173352)
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Combined Cycle Training and Inspiratory Muscle Training in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) ，the fourth leading cause of death in the world, represents an important public health challenge.
- Trial name
- NCT02200549
- Testing
- Control group, calibrated cycle ergometer, calibrated cycle ergometer and threshold loading device
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhujiang Hospital
Major Depressive Disorder
Rapid Antidepressant Effects of ATP and Phosphocreatine
This is a preliminary, double-blind clinical trail aimed to investigate whether the combination of fluoxetine with ATP or phosphocreatine has a rapid antidepressant effect.
- Trial name
- NCT03138681
- Testing
- ATP, Phosphocreatine
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Zhujiang Hospital
Liver Diseases, Pancreatic Diseases
Application of 3D Visualization and 3D Printing in the Hepatobiliary and Pancreatic Surgery
Background:The aim of the study is to value the application of three-dimensional visualization and three-dimensional printing in the hepatobiliary and pancreatic surgery.Method：From January 2016 to December 2018,the clinical data…
- Conditions
- Liver Diseases, Pancreatic Diseases, Biliary Tract Diseases
- Trial name
- NCT03074708
- Testing
- 3D visualization and 3D printing
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhujiang Hospital
Renal Insufficiency, Chronic, Nephrotic Syndrome
Rituximab Combined With MSCs in the Treatment of PNS (3-4 Stage of CKD)
Primary nephrotic syndrome(PNS) is a group of clinical symptoms caused by a variety of factors, including immune,environmental, genetic, et al.
- Trial name
- CKD (NCT02966717)
- Testing
- Rituximab, conventional therapy, Mesenchymal stem cells
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Zhujiang Hospital
Bronchial Asthma
Treatment Efficacy of Budesonide/Formoterol in Cough Variant Asthma and Typical Asthma Patients
Bronchial asthma is a common respiratory disease characterized by chronic airway inflammation, which have been affecting about 1-18% of the population in the world, causing tremendous economic burden for the patients and…
- Trial name
- NCT02934945
- Testing
- budesonide 160μg/formoterol 4.5μg
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhujiang Hospital
Bacterial Infection, Critically Ill
Study of Tigecycline Pharmacokinetics in Patients Undergoing Continuous Renal Replacement Therapy(CRRT)
The aim of this study is to determine the Pharmacokinetics/Pharmacodynamics(PK/PD) of tigecycline in critical ill patients undergoing continuous renal replacement therapy（CRRT）and examine whether the dosage needs adjustment.
- Trial name
- NCT02931526
- Testing
- Tigecycline
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhujiang Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Effects of CPAP Level on Respiratory Mechanics and Central Drive in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a common respiratory disease characterized by airflow limitation that is progressive and not fully reversible.
- Trial name
- NCT02285400
- Testing
- CPAP level
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhujiang Hospital
Asthma
Assessment of Airway Responsiveness and Treatment Efficacy in Asthmatics
Bronchial asthma is a common chronic respiratory disease. Patients usually manifest variable symptoms (such as short of breath, chest tightness, cough, etc.) and variable airflow limitation and often associated with airway…
- Trial name
- NCT02574975
- Testing
- methacholine, adenosine monophosphate, leukotriene D4
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhujiang Hospital
Pulmonary Disease，Chronic Obstructive;
Small Airways Evaluation and Treatment
Chronic obstructive pulmonary disease (COPD) is a common disease , and characterized by progressive development of airflow limitation.
- Trial name
- NCT02526758
- Testing
- beclomethasone, formoterol, budesonide
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhujiang Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Ventilation-drive Coupling to Evaluate The Efficacy of Inhaled Bronchodilators in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of chronic morbidity, mortality and disability throughout the world, leading to a heavy social and economic burden.Bronchodilators, the most commonly used drugs in…
- Trial name
- NCT02296047
- Testing
- ipratropium bromide, salbutamol
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Zhujiang Hospital
Hemangioma
Clinical Characteristics of Lip Hemangiomas
Lip hemangiomas are at higher risk than those located in other sites. However, studies about clinical characteristics of lip hemangiomas have not been enough.
- Trial name
- NCT02351245
- Testing
- observation
- Volunteers
- 39 people
- Sponsor
- Zhujiang Hospital
Chronic Obstructive Pulmonary Disease(COPD)
Effects of Inspiratory and Expiratory Pressure Training Methods in Patients With Chronic Obstructive Pulmonary Disease
The study will investigate the effects of different training types ,including combined inspiratory with expiratory pressure threshold training,inspiratory pressure threshold training on patients with chronic obstructive airway…
- Trial name
- NCT02326181
- Testing
- inspiratory pressure training group, mixed training group
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhujiang Hospital
Chronic Obstructive Pulmonary Disease
Association Between CytochromeP4501A2 and CytochromeP4502E1 Gene Polymorphisms and Metabolism of Theophylline
The aim of this study is to determine whether common CYP1A2 and CYP2E1 gene polymorphisms effect metabolism of theophylline in chronic obstructive pulmonary disease patients.
- Trial name
- NCT02001935
- Testing
- theophylline
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Zhujiang Hospital
Chronic Obstructive Pulmonary Disease, Asthma
Drug Interaction Study of Azithromycin and Theophylline
Macrolides are potent inhibitors of cytochrome P450 isoenzyme 3A4（CYP3A4）and thus interfere with the pharmacokinetics of many other drugs that are metabolised by this enzyme like theophylline.The aim of this study is to determine…
- Trial name
- NCT02023554
- Testing
- Theophylline with azithromycin, Theophylline alone
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhujiang Hospital
Hemodynamics, Oxidative Stress
Effect of Induction and Maintenance of Anesthesia With Etomidate on Hemodynamics and Oxidative Stress in Diabetic Patients
To explore the effect of induction and maintenance of anesthesia with etomidate on hemodynamics and oxidative stress in diabetic patients.
- Conditions
- Hemodynamics, Oxidative Stress, Anesthesia
- Trial name
- NCT02202239
- Testing
- midazolam, Penehyclidine Hydrochloride Injection, Etomidate
- Volunteers
- 60 people
- Sponsor
- Zhujiang Hospital
Chronic Obstructive Pulmonary Disease(COPD), Malnutrition
Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD
Insufficient energy intake and systematic inflammation lead to malnutrition in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02197871
- Testing
- enteral nutrition emulsion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhujiang Hospital
Gallstones, Cholecystitis
Role of the Right Portal Pedicle and Rouviere's Sulcus as an Anatomic Landmark in Laparoscopic Cholecystectomy
Objective:To explore the role of the right portal pedicle and Rouviere's sulcus as an anatomic landmark in laparoscopic cholecystectomy.
- Conditions
- Gallstones, Cholecystitis, Polyps
- Trial name
- NCT02133027
- Testing
- Rouviere's sulcus, surgical instruments
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhujiang Hospital