Clinical trials: sponsored by Zhujiang Hospital
Stellate Ganglion, Parkinson Disease
Clinical Study of Stellate Ganglion Block in Treatment of Patients With Advanced Primary Parkinson's Disease
At present, there are no reports on the application of stellate ganglion block in the treatment of Parkinson's disease patients at home and abroad.
- Trial name
- NCT06112392
- Testing
- Treatment （Stellate ganglion block；Oral standard anti-Parkinson's drugs）, Treatment （Oral standard anti-Parkinson's drugs）
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Extrahepatic Biliary Tree Injury
High Quality Fluorescent Cholangiography
The goal of this randomized controlled trial is to compare the quality of extrahepatic biliary fluorescent visualization under two injection protocols to optimize extrahepatic biliary cholangiography.
- Trial name
- HQFC (NCT05926856)
- Testing
- Indocyanine green
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Zhujiang Hospital
Human Microecology；Colorectal Disease；Auxiliary Diagnosis
A Multi-center Study on Human Microecology Assisted Diagnosis of Colorectal Cancer
As for this research，we want to find whether the intestinal microecology (flora, peptidoglycan fragments) have certain distribution characteristics in colorectal diseases; whether it can predict the development of disease/as a…
- Trial name
- NCT05998915
- Testing
- observe only
- Where
- China
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Prediabetes, Diabetes Mellitus
Research on Potential Biomarkers of Prediabetes and Diabetes Based on MALDI-TOF MS Platform.
Through the MALDI-TOF MS platform, explore the proteomics and peptidomics differences of fasting serum/plasma and urine between non pregnant people with normal glucose tolerance test and prediabetes /diabetes patients, pregnant…
- Conditions
- Prediabetes, Diabetes Mellitus, Gestational Diabetes Mellitus, Proteomics
- Trial name
- NCT06097065
- Testing
- Oral Glucose Tolerance Test
- Where
- China
- Volunteers
- 2,860 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Children
AI Based Multi-modal Parameter of Peripheral Blood Cells (MMPBC) Predicts Survival Risk in Critically Ill Children
This study aims to investigate whether an AI prediction model based on blood cell multi-modal data can achieve early warning of survival risk in critically ill children through a large-scale multi-center cohort of critically ill…
- Trial name
- NCT06034639
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Zhujiang Hospital
Parkinson's Disease, Overactive Bladder
Safety and Efficacy of Botulinum Toxin A for Treatment of Overactive Bladder in Parkinson's Disease
A randomized controlled trial is to be conducted to confirm the efficacy and safety of intramuscular injection of botulinum toxin in the treatment of Parkinson's bladder overactivity.
- Conditions
- Parkinson's Disease, Overactive Bladder, Onabotulinumtoxin A
- Trial name
- NCT05997043
- Testing
- oral anti-Parkinson drugs and injection of botulinum toxin, oral anti-Parkinson's drugs
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhujiang Hospital
Parkinson's Disease
Multi-chip Meta-analysis of Parkinson's Disease for Clinical Validation of Small Samples of Key Genes in Disease
The research team used meta-analytical statistical methods to integrate the results of different research groups on Parkinson's disease, using meta-analysis to find key genes related to the pathogenesis and development of…
- Trial name
- NCT03848455
- Testing
- genetic diagnosis
- Where
- China
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Healthy, Breast-milk Collection
Omics Sequencing of Specimen Derived From Mother-Infant-Pairs
The investigators aim to collect breast-milk and feces from the participants, and apply culture techniques as well as omics sequencing technology to probe into the microbial and metabolomic signature of the specimens.
- Conditions
- Healthy, Breast-milk Collection, Feces
- Trial name
- NCT05462366
- Testing
- Sample collection
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Ischemic Stroke
Autologous Bone Marrow Mesenchymal Stem Cells (BMSCs) Transplantation in the Treatment of Ischemic Stroke
This study is to evaluated the safety and efficacy of BMSCs transplantation in the treatment of ischemic stroke, so as to provide a basis for future clinical application of BMSCs transplantation in the treatment of ischemic…
- Trial name
- NCT05850208
- Testing
- Transplantation of self BMSCs
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhujiang Hospital
Hepatocellular Carcinoma Resectable
Applicability of PDOX in Patients With Primary Liver Cancer: A Randomized Controlled Trial
This Randomized Controlled Trial was to clarity the clinical feasibility of PDOX results in guiding the drug use of interventional chemotherapy after primary liver cancer surgery.
- Trial name
- NCT05766605
- Testing
- Oxaliplatin, Doxorubicin, Lobaplatin
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhujiang Hospital
Hepatobiliary Malignancies
AssesSment of Early-deteCtion basEd oN liquiD Biopsy in Hepatobiliary Cancer Malignancies
This study is a prospective, multicenter study aimed to develop and validate the performance of combined assays for cfDNA methylation markers and serum tumor markers in early hepatobiliary malignancies detection.
- Trial name
- ASCEND-Hep (NCT04835675)
- Testing
- Multi-cancer early detection test
- Where
- China
- Volunteers
- 496 people
- Sponsor
- Zhujiang Hospital
Liver, Cancer of, Primary Resectable
Applicability of 3D-HDRA in Patients With Primary Liver Cancer: A Randomized Controlled Trial
This Randomized Controlled Trial was to clarity the clinical feasibility of 3D-HDRA results in guiding the drug use of interventional chemotherapy after primary liver cancer surgery.
- Trial name
- NCT05701436
- Testing
- Oxaliplatin, Doxorubicin, Lobaplatin
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Zhujiang Hospital
Healthy, Metabolism
Effects of IAP-EOGBSD on Offspring's Gut Microbiome and Immunity.
This study is planned to be recruited in two hospitals in South China, Zhujiang Hospital of Southern Medical University and Zhongshan Boai Hospital Recruit participants, plan to recruit obstetrics and child health departments in…
- Conditions
- Healthy, Metabolism, Microbiome
- Trial name
- NCT05738460
- Testing
- antibiotics
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Zhujiang Hospital
Microbiome, Human
Effects of IAP-EOGBSD on Maternal Vaginal Microbiome, Offspring's Gut Microbiome and Metabolites.
In view of the current status of prevention and research on GBS disease in mothers and infants at home and abroad, this project intends to explore the characteristics of vaginal microbiota of GBS-colonized pregnant women in…
- Trial name
- NCT05738473
- Testing
- antibiotic
- Where
- China
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Preeclampsia, Microbiome
A Multicenter Cohort Study on Maternal and Infant Microecology and New Targets for Pre-eclampsia Screening in China
major objective This multicenter, prospective cohort study aims at evaluating the predictive value of microbiome ,proteomics and serum markers in preeclampsia.
- Trial name
- CALM2001 (NCT05445544)
- Testing
- Observational studies, The diagnosis was preeclampsia
- Where
- 2 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Vitamin C, COVID-19 Pneumonia
Efficacy of Megadose Vitamin C in Severe and Critical Ill COVID-19 Patients.
The main aim is to determine whether vitamin C can reduce 28-day all-cause mortality or persistent organ dysfunction compared with placebo in patients with severe and critical ill COVID-19 patients.
- Trial name
- NCT05694975
- Testing
- Vitamin C
- Where
- 4 sites in China
- Volunteers
- 608 people
- Sponsor
- Zhujiang Hospital
Intracranial Tumors
AssesSment of Early deteCtion basEd oN liquiD Biopsy in Intracranial Tumors
ASCEND-BRAIN is a prospective, observational study aimed at early-detection of intracranial tumors by combined assays of cfDNA methylation and other biomarkers.
- Trial name
- ASCEND-BRAIN (NCT05679089)
- Testing
- early detection test
- Where
- China
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Hepatocellular Carcinoma Non-resectable
Efficacy and Safety of Transarterial Therapies+Donafenib + Anti-PD-1 Antibody for uHCC: A Retrospective Real-world Study
This Retrospective Real-world study was designed to evaluate the clinical efficacy and safety of the Combination of transarterial therapies with donafenib plus Anti-PD-1 Antibody for Unresectable Hepatocellular Carcinoma.
- Trial name
- NCT05638438
- Testing
- transarterial therapies
- Volunteers
- 100 people
- Sponsor
- Zhujiang Hospital
Sepsis
Effects of Dietary Fiber on Bone Metabolism
Clinical and animal studies have found that sepsis can lead to a serious imbalance in the gut microecology, a reduction in probiotics, a reduction in short-chain fatty acid, a reduction in bone mass, and an increase in bone…
- Trial name
- NCT05623098
- Testing
- dietary fiber nutrients
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Zhujiang Hospital
Gastrointestinal Disease
The Treatment of Acute Gastrointestinal Injury Via Ultrasound-guided Erector Spinae Plane Block
In this single-center, randomized, parallel control clinical trial, patients will be randomly assigned to two groups. The treatment group receives ultrasound-guided erector spinae plane block with routine treatment of Acute…
- Trial name
- NCT04934904
- Testing
- Ropivacaine injection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhujiang Hospital