Clinical trials: sponsored by Emory University
Stress
Imaging Cerebral and Sub-cerebral Correlates of Meditative States
Three groups of subjects are trained to practice mindfulness meditation, compassion meditation, or attend a health training control class.
- Trial name
- calm (NCT01262404)
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Childhood Apraxia of Speech, Verbal Apraxia
Role of Omega-DEK in Childhood Apraxia of Speech
This is a 20-week study for children between 3 and 6 years old with confirmed childhood apraxia of speech (CAS). The study includes a 12-week open-label pilot feasibility study of an investigational drug (Omega-DEK) plus…
- Conditions
- Childhood Apraxia of Speech, Verbal Apraxia, Autism
- Trial name
- NCT07216001
- Testing
- Omega-DEK, L-carnitine
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Claudia R. Morris
Raynaud Phenomenon
Botulinum Toxin in Raynaud's Phenomenon
Raynaud's Phenomenon (RP) is the most common vasospastic disorder encountered by hand surgeons with an estimated prevalence of 5% in the general population. It's manifestations are broad, and can range from minor to severe.
- Trial name
- NCT05125029
- Testing
- Botulinum toxin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Sickle Cell Disease
Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease
The purpose of this study is to determine whether giving extra arginine to patients with sickle cell disease seeking treatment for vaso-occlusive painful events (VOE) will decrease pain scores, decrease need for pain medications…
- Trial name
- R34 pK/PD (NCT02447874)
- Testing
- Arginine, Arginine (Loading), Arginine (Continuous)
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Emory University
Heart Failure
Tailored Electronic Intervention to Improve Therapy in a Diverse Cohort of Patients With Heart Failure
Recent medical guidelines for the management of heart failure (HF) have established a combination of specific classes of medications as the best treatment for patients with heart failure with reduced ejection fraction (HFrEF).
- Trial name
- TAILORD-HF (NCT06847438)
- Testing
- Optimized version of the EPIC-HF Checklist, Clinician-facing Decision Support, Standard of Care
- Where
- 4 sites in United States
- Volunteers
- 3,966 people
- Sponsor
- Emory University
Myocardial Infarction
Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis
The purpose of this study is to look at the link between emotional stress and heart disease in men and women. Taking part in this study involves one clinic visit, one week of at home monitoring, and follow up phone calls every 6…
- Trial name
- MIMS3 (NCT04123197)
- Testing
- Stress Challenge
- Where
- 3 sites in United States
- Volunteers
- 306 people
- Sponsor
- Emory University
Sexually Transmitted Infections, Gay
HIV/STD Risk and PrEP Implementation Messaging Among Gay, Bisexual, and Other Men Who Have Sex With Men
The goal of this observational study is to learn about awareness around PrEP use and adherence, condom use, sexual risk-taking behavior, and substance-using behaviors in men having sex with men.
- Conditions
- Sexually Transmitted Infections, Gay, Pre Exposure Prophylaxis
- Trial name
- MIC-DROP (NCT06183502)
- Testing
- Quantitative survey, HIV and STI testing, Qualitative Assessment
- Where
- 3 sites in United States
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Emory University
Old Age
Inspiring Seniors Towards Exercise Promotion - 2
Older adults' low adherence to the national physical activity guidelines may stem from a failure to increase positive affective responses to exercise (e.g., enjoyment).
- Trial name
- iSTEP-2 (NCT07629739)
- Testing
- Exercise intervention with RAS (EX+RAS), Exercise intervention without RAS (EX)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Emory University
Multiple Myeloma
Evaluating Premedication Regimens (Methylprednisolone vs Dexamethasone-based) for the Prevention of Systemic and Injection Site Reactions to Motixafortide in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization, PARADE Trial
This phase IV trial compares the effect of premedication regimens with methylprednisolone versus dexamethasone for the prevention of allergic reaction to motixafortide in patients with multiple myeloma (MM) undergoing stem cell…
- Trial name
- NCT07101445
- Testing
- Acetaminophen, Biospecimen Collection, Dexamethasone
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Emory University
Violence, Sexual
Strategies for Implementing GlobalConsent to Prevent Sexual Violence in University Men
This project, SCALE, will be the first to compare lower-intensity (standard) and higher-intensity implementation strategies to deliver GlobalConsent-an efficacious web-based sexual violence prevention program-to men attending…
- Trial name
- SCALE (NCT06443541)
- Testing
- High-intensity implementation strategies (HIS)-Students, Low-intensity implementation strategies (LIS) for Students, High-intensity implementation strategies (HIS) for Faculty
- Where
- 7 sites in Vietnam
- Volunteers
- 3,439 people, healthy volunteers welcome
- Sponsor
- Emory University
Heart Failure, Diabetes Mellitus
CGM Use in Heart Failure
Heart failure (HF) is a major cause of hospital admissions in the US, with over 6 million hospital days annually. More than 40% of hospitalized patients with HF have diabetes mellitus (DM), which increases the risk of recurrent…
- Trial name
- NCT07045298
- Testing
- Libre 2 rt-CGM, POC BG + Blinded CGM
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Emory University
Pulmonary Hypertension, Pulmonary Hypertension Due to Lung Diseases
Bioenergetic Effect of Pioglitazone in CLD-PH
The goal of this clinical trial is to learn about the safety and efficacy of Pioglitazone in people with Pulmonary Hypertension (PH) due to Chronic Lung Disease (CLD).
- Trial name
- NCT06336798
- Testing
- Pioglitazone 30mg, Labs
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Asthma in Children, Asthma Attack
Wearable Electronic Breath Sound Sensing Device
This study will assess the ability of a wearable stethoscope to monitor wheezing in high-risk asthma patients admitted at Children's Healthcare of Atlanta.
- Trial name
- WEBSS (NCT06734793)
- Testing
- Wearable stethoscope, Routine Clinical lung Auscultation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Emory University
Obesity
Active You: Walk, Dance, and Tone Your Abs to Reduce Your Risk of Diabetes
The phenomenon of physical activity (PA) avoidance in obesity has been detailed in the literature, but there is a lack of programs designed to address the root causes.
- Trial name
- NCT06127251
- Testing
- PATH Intervention, Control Group, Physical activity tracker
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Emory University
PTSD, Trauma
Neuroendocrine Risk for PTSD in Women
This study will test for effects of estradiol (E2) on PTSD symptoms and functional magnetic resonance imaging (fMRI) indicators of stress vulnerability, in naturally-cycling women who are not using hormonal birth control.
- Trial name
- NCT03973229
- Testing
- Estradiol patch
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Emory University
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer
This early phase I trial tests whether letrozole with simvastatin works better than letrozole alone to stop tumor cell proliferation in patients with stage I-III hormone receptor positive, HER2 negative invasive breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma
- Trial name
- NCT05464810
- Testing
- Letrozole, Simvastatin
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Emory University
Vaccine Response
Durability of Vaccine Responses
The ability of the vaccines today to generate a long-lasting protection against infections varies greatly from one vaccine to another.
- Trial name
- NCT05801978
- Testing
- Live Attenuated Yellow Fever 17D Vaccine, Quadrivalent seasonal influenza vaccine
- Where
- 3 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Emory University
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Cutaneous Squamous Cell Carcinoma of the Head and Neck
Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation
This clinical trial tests the impact of offering hearing tests (audiometry) close to home and remotely on participation in monitoring for treatment-related hearing loss in patients with head and neck squamous cell cancer…
- Conditions
- Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Cutaneous Squamous Cell Carcinoma of the Head and Neck, Head and Neck Carcinoma of Unknown Primary, Head and Neck Squamous Cell Carcinoma
- Trial name
- NCT06662058
- Testing
- Audiometric Test, Interview
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Emory University
Post-stroke Hemiparesis
Innovative Closed-loop Functional Electrical Stimulation Control System for Augmenting Post-stroke Gait
This study will compare the performance of a novel data-driven model-predictive controller (MPC) based functional electrical stimulation (FES) system versus a conventional FES system for footdrop correction during treadmill and…
- Trial name
- NCT07189819
- Testing
- Model-Predictive Controller (MPC) Functional Electrical Stimulation (FES), Conventional Functional Electrical Stimulation (FES)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Squamous Cell Carcinoma of the Head and Neck
VX15/2503 in Combination With Ipilimumab or Nivolumab in Patients With Head and Neck Cancer
This phase I trial studies how well anti-semaphorin 4D (SEMA4D) monoclonal antibody VX15/2503 (VX15/2503) with or without ipilimumab and/or nivolumab work in treating patients with stage I-IVA head and neck squamous cell cancer.
- Trial name
- NCT03690986
- Testing
- VX15/2503, Ipilimumab, Nivolumab
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Emory University
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