Clinical trials: sponsored by UNICANCER
Breast Cancer
Docetaxel in Treating Older Women With Metastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00104624
- Testing
- docetaxel, quality-of-life assessment
- Where
- 7 sites in France, Italy and 1 more
- Volunteers
- 53 people
- Sponsor
- UNICANCER
Breast Cancer
Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as trastuzumab can locate tumor cells and either kill them or deliver…
- Trial name
- NCT00054587
- Testing
- Trastuzumab, Cyclophosphamide, docetaxel
- Where
- 29 sites in France
- Volunteers
- 3,010 people
- Sponsor
- UNICANCER
Breast Cancer
Combination Chemotherapy in Treating Women With Stage I Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00055679
- Testing
- cyclophosphamide, epirubicin hydrochloride, fluorouracil
- Where
- 72 sites in France
- Volunteers
- 1,512 people
- Sponsor
- UNICANCER
Breast Cancer
Trastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be Removed By Surgery
RATIONALE: Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00674414
- Testing
- trastuzumab, everolimus, therapeutic conventional surgery
- Where
- 8 sites in France
- Volunteers
- 82 people
- Sponsor
- UNICANCER
Breast Cancer, Metastatic Cancer
Lapatinib Ditosylate and Capecitabine in Treating Patients With Stage IV Breast Cancer and Brain Metastases
RATIONALE: Lapatinib ditosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00967031
- Testing
- capecitabine, lapatinib ditosylate, circulating tumor cell analysis
- Where
- France
- Volunteers
- 45 people
- Sponsor
- UNICANCER
Naive Unresectable Glioblastoma
Evaluation of the Irinotecan/Bevacizumab Association for Naive Unresectable Glioblastoma
Treatment of glioblastoma (GBM) is based on surgery when possible, and chemoradiation with temozolomide, which became a standard since the EORTC study (Stupp, 2005).
- Trial name
- TemAvIr (NCT01022918)
- Testing
- Avastin + Campto / radiotherapy + Temodal + Avastin (4 cures), Temodal/radiotherapy
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Centre Georges Francois Leclerc
Stage IB2 Cervical Cancer, Stage II Cervical Cancer
Evaluation of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer
GYNECO 02 hypothesis is that hysterectomy reduces the possibility of local or loco-regional relapse, especially in patient with a reduced metastatic risk and who received a local chemoradiation therapy with an increase of…
- Conditions
- Stage IB2 Cervical Cancer, Stage II Cervical Cancer, Adenocarcinoma, Squamous Cell Carcinoma
- Trial name
- NCT01363466
- Testing
- hysterectomy
- Where
- 35 sites in France
- Volunteers
- 61 people
- Sponsor
- UNICANCER
Compensated Cirrhosis
Screening of Hepatocellular Carcinoma in Patients With Compensated Cirrhosis
Liver carcinoma is becoming the main complication of cirrhosis. Treatment of symptomatic or large tumors is disappointing. Regular ultrasonographic screening of small (curable) tumors is currently recommended, but the best…
- Trial name
- NCT00190385
- Testing
- Ultrasonographic screening
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris