Clinical trials: sponsored by Emory University
Depression
Mechanisms of Behavioral Activation (BA)
The investigators will be comparing brain (neural) activation of depressed adolescent patients before, during and after a course of Behavioral Activation (BA) therapy using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT05548244
- Testing
- Behavioral Activation Therapy, Baseline assessment procedures
- Where
- 3 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Emory University
Smoldering Plasma Cell Myeloma
Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma
This phase II trial studies the effects of iberdomide when given alone or in combination with dexamethasone in treating intermediate or high-risk smoldering multiple myeloma patients.
- Trial name
- NCT04776395
- Testing
- Dexamethasone, Iberdomide Hydrochloride, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Emory University
Caregiver Burden
Caregiving While Black
The goal of this project is to revise and test an online education program designed to enhance the mastery of Black American caregivers to provide care to family members or friends living with a dementia illness.
- Trial name
- NCT05772689
- Testing
- Usual Care, Caring While Black
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Emory University
Post Traumatic Stress Disorder
Effect of TMS on PTSD Biomarkers
The study will (1) assess feasibility of a TMS treatment in an underserved population; (2) determine if this TMS treatment protocol improves PTSD symptoms and biological markers of PTSD such as brain functioning and startle…
- Trial name
- NCT04563078
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Metabolic-dysfunction Associated Steatotic Liver Disease
SMART Diets for MASLD
This phase 2 trial is a single-site sequential, multiple assignment, randomized trial (SMART) to test and construct a high-quality adaptive intervention of essential amino acids (EAA) and/or Low Sugar Diet for children with…
- Trial name
- NCT07459504
- Testing
- Essential Amino Acids Supplementation intervention, Low sugar diet
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Michigan State University
HIV Infections, Mental Health
Testing the WeCare Intervention to Address Mental Health and Medication Adherence Challenges Among MSM in South Africa
The goal of this clinical trial is to learn if the WeCare intervention-an adapted Friendship Bench program that integrates problem-solving therapy, minority-stress-informed content, and explicit PrEP/ART adherence skills-improves…
- Trial name
- NCT07226323
- Testing
- WeCare, Standard of Care
- Where
- South Africa
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV, Depression
Inflammation and Depression in People With HIV
The purpose of this 10-week, double-blind, placebo-controlled study is to determine whether inflammation impacts reward and motor neural circuitry to contribute to depressive symptoms like anhedonia and psychomotor slowing in…
- Conditions
- HIV, Depression, Anhedonia
- Trial name
- NCT05849038
- Testing
- Baricitinib
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Emory University
Clostridium Difficile Infection
A Screening and Recruitment Study in Adults Expressing Interest in the Emory Microbiota Enrichment Program
The goal of this study is to rapidly identify subjects who are eligible for the Microbiota Enrichment Program (MEP) at Emory in Atlanta, Georgia.
- Trial name
- MEP (NCT03350711)
- Testing
- Microbiota Enrichment Program (MEP)
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Emory University
Mild Cognitive Impairment
PRogram to Improve Stress-levels and Enhance Memory
This is a pilot study with the objective to examine if an in-person and a remote multi-component intervention program can improve chronic stress, vascular measures, and executive function among African American and White patients…
- Trial name
- PRISEM (NCT05845918)
- Testing
- PRISEM Remote
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Emory University
Malignant Solid Neoplasm
Transportation for Cancer Care Navigation Tool for Reducing Travel Barriers Among Patients With Solid Tumors Receiving Radiation Therapy
This clinical trial evaluates whether the Transportation for Cancer Care Navigation Tool (TRACT) can reduce travel barriers among patients with solid tumors receiving radiation therapy.
- Trial name
- TRACT (NCT06541158)
- Testing
- Best Practice, Discussion, Educational Intervention
- Where
- 4 sites in United States
- Volunteers
- 76 people
- Sponsor
- Emory University
Knee Disease, Knee Infection
F18-MHF: Implants-Associated Infection Detection
Following intravenous injection of [F-18]MHF as a bolus, dynamic PET imaging of the lower limbs will be acquired for approximately 90 minutes. The acquired images will be processed and viewed on a MIMVista or similar workstation.
- Trial name
- NCT05889286
- Testing
- [F-18]MHF
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Emory University
Body Composition, Feeding; Difficult, Newborn
Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficulty
Large for Gestational Age (LGA) infants have excess fat-mass (FM) proportion secondary to prolonged in utero exposure to an energy-rich environment.
- Conditions
- Body Composition, Feeding; Difficult, Newborn, Nutrition Disorder, Infant
- Trial name
- NCT04599010
- Testing
- Dietary intervention
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Prodromal Alzheimer's Disease
Partnered Rhythmic Rehabilitation in Prodromal Alzheimer's Disease
Interventions that affect many different aspects of human ability rather than just one aspect of human health are more likely to be successful in preventing and treating Alzheimer's disease (AD).
- Trial name
- NCT04029623
- Testing
- Partnered Rhythmic Rehabilitation (PRR), Group walking (WALK)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Emory University
End Stage Renal Disease (ESRD), Kidney Disease
RaDIANT Health Systems Intervention
The overarching goal of the proposed study is to determine whether the addition of structural interventions at the health system level targeting upstream barriers in the transplant process will improve access to transplant…
- Trial name
- NCT07033117
- Testing
- Performance Feedback Reports on Referral and Evaluation Closures, Dialysis Facility Awareness Campaign, Patient Contact via Preferred Method
- Where
- 5 sites in United States
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- Indiana University
Muscle Tension Dysphonia
Voice Therapy Per the Rehabilitation Treatment Specification System
The goal of this study is to evaluate if using evidence-based, standard ingredient and target codes from the Rehabilitation Treatment Specification System - Voice Therapy (RTSS-Voice) in standard of care voice therapy…
- Trial name
- RTSS-Voice (NCT06152627)
- Testing
- Standard of care voice therapy with novice clinician RTSS-Voice documentation, Standard of care voice therapy with expert clinician RTSS-Voice documentation
- Where
- 5 sites in United States
- Volunteers
- 600 people
- Sponsor
- Massachusetts General Hospital
Post Traumatic Stress Disorder
MDMA-Assisted Massed Exposure Therapy for PTSD
The goal of this clinical trial is to investigate the efficacy of 3,4-methylenedioxy-methamphetamine hydrochloride (MDMA) combined with Massed Prolonged Exposure (PE) therapy for the treatment of posttraumatic stress disorder…
- Trial name
- NCT07288151
- Testing
- 3,4-Methylenedioxymethamphetamine (MDMA), Massed Prolonged Exposure (PE)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Emory University
Parkinson Disease
Zesty Exercise System for Therapeutic Engagement
This study will evaluate exercise delivered through the Zesty Exercise System for Therapeutic Engagement (ZEST-E) for people with Parkinson's disease when sessions are monitored either in person or remotely.
- Trial name
- ZEST-E (NCT07382674)
- Testing
- ZEST-E Robot-Assisted Exercise Program
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Emory University
Alzheimer's Disease
Tango for Alzheimer's Disease Patients' Caregivers
The goal of the project is to determine the extent to which indices of inflammatory biomarkers, cognition and mood, are influenced by a partnered, dance-based intervention vs control condition in African American (AA) female…
- Trial name
- NCT03269149
- Testing
- Adapted Tango Dance, Educational lectures
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Major Depressive Disorder
Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine
The main purpose of this study is to investigate the effects of ketamine on decision-making and emotion processing in a sample of individuals diagnosed with Major Depressive Disorder (MDD).
- Trial name
- NCT05327699
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Emory University
Hypogonadism, Malignant Urinary System Neoplasm
Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone
This phase I trial investigates the safety of testosterone replacement therapy around the time of major urologic surgery (perioperative) in order to improve quality of life and post-operative outcomes such as decreased length of…
- Conditions
- Hypogonadism, Malignant Urinary System Neoplasm, Urinary System Disorder, Urinary System Neoplasm
- Trial name
- NCT04731376
- Testing
- Best Practice, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Emory University
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