Clinical trials: sponsored by Jazz Pharmaceuticals
Fibromyalgia
Safety and Efficacy Study of Xyrem® (Sodium Oxybate) in Subjects With Fibromyalgia.
The objective of this trial is to evaluate the safety and efficacy of Xyrem® in long term use.
- Trial name
- NCT00423605
- Testing
- Xyrem®
- Where
- 91 sites in United States, France and 5 more
- Volunteers
- 560 people
- Sponsor
- Jazz Pharmaceuticals
Coronary Artery Stenosis
Comparing the Protective Effects of Two Cardioplegic Solutions, on Cardiac Metabolism, as Assessed Using Microdialysis
An estimated 8% to 15% of patients hospitalized for a coronary pathology undergo coronary revascularization surgery with extracorporeal circulation (ECC).
- Trial name
- Cardioplégie (NCT01401140)
- Testing
- St Thomas, Custodiol
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Obstructive Sleep Apnea Syndrome
Trial of Effects of Oral Xyrem and Zolpidem on Sleep-Disordered Breathing in Obstructive Sleep Apnea Patients
To study the effect of Xyrem (9 g), Xyrem (9 g) plus modafinil 200 mg administered the morning prior to Xyrem, positive control (zolpidem 10 mg), and placebo on the frequency and outcome of events of sleep-disordered breathing in…
- Trial name
- NCT00086281
- Testing
- Xyrem (X), Zolpidem (Z), Modafinil (M)
- Where
- 2 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Jazz Pharmaceuticals
Fibromyalgia
Trial Comparing the Effects of Xyrem (Sodium Oxybate) With Placebo for the Treatment of Fibromyalgia
The purpose of this study is to determine whether Xyrem (sodium oxybate) is effective when used alone to treat the pain and sleep disturbances of fibromyalgia.
- Trial name
- NCT00087555
- Testing
- Xyrem (sodium oxybate) oral solution
- Where
- 20 sites in United States
- Volunteers
- 195 people
- Sponsor
- Jazz Pharmaceuticals
Fibromyalgia
A Safety and Efficacy Study of Xyrem® (Sodium Oxybate) to Treat Fibromyalgia.
The objective of this trial is to evaluate the safety and efficacy of Xyrem® compared to placebo for the treatment of fibromyalgia in a randomized, double blind, placebo controlled, parallel group trial.
- Trial name
- NCT00423813
- Testing
- Xyrem®
- Where
- 116 sites in United States, France and 6 more
- Volunteers
- 573 people
- Sponsor
- Jazz Pharmaceuticals
Essential Tremor
Multiple-dose,Double-blind,Placebo-controlled Study of Sodium Oxybate in Patients With Essential Tremor
To determine the relationship between drug plasma levels and safety, tolerability and efficacy in patients with essential tremors after dosing with Sodium oxybate
- Trial name
- NCT00598078
- Testing
- Sodium Oxybate
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Jazz Pharmaceuticals
Fibromyalgia
A Safety and Efficacy Study of Xyrem® in Subjects With Fibromyalgia
The objective of this trial is to evaluate the safety and efficacy of Xyrem® compared to placebo for the treatment of fibromyalgia in a randomized, double blind, placebo controlled, parallel group trial.
- Trial name
- NCT00371137
- Testing
- Xyrem®
- Where
- 70 sites in United States
- Volunteers
- 548 people
- Sponsor
- Jazz Pharmaceuticals
Narcolepsy
Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in Narcolepsy
This study will be conducted as a randomized, double blind, double-dummy, placebo-controlled, parallel-group trial in patients diagnosed with narcolepsy.
- Trial name
- NCT00066170
- Testing
- Xyrem, Modafinil at established dose
- Where
- 40 sites in United States, France and 2 more
- Volunteers
- 231 people
- Sponsor
- Jazz Pharmaceuticals
Fibromyalgia
Safety and Tolerability Study Comparing Sodium Oxybate Given as an Oral Solution to a Single-blinded Combination of Oral Tablets Plus Oral Solution in Subjects With Fibromyalgia
To compare the safety and tolerability of sodium oxybate given as a combination of an oral solution and oral tablets for 4 weeks in subjects with fibromyalgia (FM).
- Trial name
- NCT00803023
- Testing
- Sodium Oxybate, Sodium Oxybate & 6 Tablets, Sodium Oxybate & 8 Tablets
- Where
- 32 sites in United States
- Volunteers
- 129 people
- Sponsor
- Jazz Pharmaceuticals
Healthy
A Safety, Tolerability and Pharmacokinetic Study of a Single Dose of CMX157 in Healthy Volunteers
The purpose of this study is to evaluate the safety and tolerability of CMX157 and the amount of CMX157 that reaches the blood stream, the manner in which the body processes CMX157 and the time that it takes to eliminate CMX157…
- Trial name
- NCT01080820
- Testing
- CMX157, Viread
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jazz Pharmaceuticals
Binge Eating Disorder
Sodium Oxybate in the Treatment of Binge Eating Disorder
The purpose of this research study is to study the effectiveness, tolerability and safety of sodium oxybate in outpatients with binge eating disorder.
- Trial name
- NCT00514995
- Testing
- Sodium Oxybate
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Lindner Center of HOPE
Hepatic Veno-Occlusive Disease
Pediatric Trial Investigating the Incidence & Outcome of Veno-Occlusive Disease With the Prophylactic Use of Defibrotide
The aim of this trial is to evaluate whether the prophylactic use of Defibrotide (DF) in pediatric patients (age less than 18 years) undergoing stem cell transplantation and who are at high risk of developing hepatic…
- Trial name
- VOD-DF (NCT00272948)
- Testing
- Defibrotide
- Where
- 30 sites in Austria, France and 8 more
- Volunteers
- 360 people
- Sponsor
- European Society for Blood and Marrow Transplantation
Healthy
Comparative Bioavailability and Effect of Food on CMX001 in Healthy Volunteers
The purpose of this study is to compare the bioavailability of CMX001 when administered as a tablet vs a solution and to determine the effect of a high-fat meal on CMX001 bioavailability.
- Trial name
- NCT00780182
- Testing
- CMX001
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jazz Pharmaceuticals
Oral Mucositis
Caphosol for the Reduction of Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer
Patients who have been diagnosed with a head and/or neck cancer commonly develop oral mucositis (OM). The purpose of this study is to estimate the effect of Caphosol on OM and to evaluate if Caphosol had any effect on clinical…
- Trial name
- NCT00901732
- Testing
- Caphosol
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Jazz Pharmaceuticals
Sleep
Enhancing Slow Wave Sleep With Sodium Oxybate
The purpose of this study is to determine if there the impact of sleep deprivation upon sleepiness, attention, memory, and mood is reduced by pharmacologically enhancing slow wave sleep (SWS) with sodium oxybate.
- Trial name
- NCT00506974
- Testing
- sodium oxybate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Anxiety Disorder
A Long-Term Study Continuing on From Study 04-001-01 of an Experimental Medication in Adults With Anxiety Disorder
The purpose of the study is to assess the safety and effectiveness of the experimental drug, a benzodiazepine drug, in long-term use and the effects on quality of life, social and occupational functioning, sleep, and daytime…
- Trial name
- NCT00106860
- Testing
- a benzodiazepine drug
- Where
- 13 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Jazz Pharmaceuticals