Clinical trials: not yet recruiting
Psychological Distress Among Undergraduate Students
A Randomized Controlled Trial of Group Psychological Intervention to Reduce Burnout Among Nursing Undergraduates
This is a randomized controlled trial. The study aims to explore the effect of psychological intervention on the sense of distress among college students who have psychological stress in the past two weeks.
- Trial name
- NCT07910032
- Testing
- Intervention program for psychological distress among nursing undergraduates, Routine mental health education
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Liu Jingying
Non-Small Cell Lung Cancer
Risk-Adapted Segmental Esophagus-Sparing Radiotherapy for Definitive Non-Small Cell Lung Cancer
This is a multicenter, open-label, randomized, phase 3 superiority trial. The purpose is to find out whether a risk-adapted segmental esophagus-sparing radiotherapy plan is better than a standard radiotherapy plan at reducing…
- Trial name
- ES-SPARE (NCT07908732)
- Testing
- Risk-Adapted Segmental Esophagus-Sparing IMRT/VMAT, Standard IMRT/VMAT Without Active Esophageal Avoidance
- Volunteers
- 140 people
- Sponsor
- Ruijin Hospital
Hypertension (HTN), Blood Pressure
Team-Based Shared Decision-Making Program in Hypertension Control (Healthy Heart - BP Program)
The main goal of the study is to conduct a pilot trial to test the feasibility of the Team-Based Shared Decision-Making (SDM) Program, supported by Healthy Heart, involving 90 adults with uncontrolled hypertension (HTN) at…
- Trial name
- SDM in BP (NCT07909161)
- Testing
- Pharmacist-led Team-Based SDM on health behavior change and medication management for HTN control, Nurse-led Team-Based SDM on health behavior change and medication management for HTN control, Telehealth SDM visits focus on medication management and health behavior change
- Volunteers
- 90 people
- Sponsor
- Johns Hopkins University
Colorectal Neoplasms, Neoplasms
Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy
Background: Cancers that begin in the colon, adrenal glands, or bile ducts may spread to the liver. These liver tumors are often treated using a hepatic artery infusion (HAI) pump.
- Conditions
- Colorectal Neoplasms, Neoplasms, Intrahepatic Cholangiocarcinoma, Adrenocortical Carcinoma
- Trial name
- NCT07715903
- Testing
- Carfilzomib
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Cancer Institute (NCI)
Healthy Volunteer
Discovering Determinants of Food Intake by Application of Artificial Intelligence to Complex, High-Dimensional Data
Background: Many people in the United States are overweight or obese. Researchers want to learn why some people can overeat and not gain weight, whereas others who do not overeat still gain weight.
- Trial name
- NCT07637656
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Overweight, Lipid Metabolism
Effects of Concurrent Training on Serum PCSK9 Levels in Adults With Overweight
Being overweight can increase the risk of heart disease. PCSK9 is a protein that helps regulate cholesterol levels in the blood. Exercise may affect PCSK9 levels, but previous studies have reported conflicting results.
- Conditions
- Overweight, Lipid Metabolism, Cholesterol Metabolism
- Trial name
- NCT07910916
- Testing
- Concurrent Aerobic and Resistance Training
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Pregnancy, Substance Use Disorder (SUD)
Justice Core Trial
The goal of this clinical trial is to learn if Justice Core, an intervention that moves pregnant women with substance use disorder (SUD) from jail into community-based SUD treatment while awaiting trial, can improve the health of…
- Conditions
- Pregnancy, Substance Use Disorder (SUD), Prisoners
- Trial name
- NCT07911332
- Testing
- Jail Diversion into Treatment, Referral at Release
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of North Carolina, Chapel Hill
Non Specific Neck Pain
Effects of Cervical SNAGs With and Without Thoracic Manipulation on Neck Pain and Disability in Smartphone Users
Non-specific neck pain is a pain and discomfort in the cervical spinal area that arises without trauma, clearly identifiable pathological cause such as fracture infection, nerve root compression, inflammatory disease or serious…
- Trial name
- NCT07909759
- Testing
- Cervical SNAGS and thoracic manipulation with conventional physiotherapy, Cervical SNAG Mobilization Alone + Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Management and Technology Lahore
Cardiovascular Diseases, Cardiac Rehabilitation
Threshold-Based Versus Range-Based Exercise Intensity Prescription in Cardiac Rehabilitation
Cardiac rehabilitation is an important part of the treatment of patients with cardiovascular disease. Supervised aerobic exercise improves physical fitness, functional capacity, and quality of life.
- Trial name
- T-REXI-CR (NCT07908810)
- Testing
- Threshold-Based Aerobic Exercise Intensity Prescription, Range-Based Aerobic Exercise Intensity Prescription
- Where
- 9 sites in Belgium
- Volunteers
- 230 people
- Sponsor
- Hasselt University
Brain Injuries
Implementation Study on Hospital-to-home Advanced Rehabilitation Technologies (ART)
To study the feasibility of the various model of ART rental service for home use, prescribed and supervised by experienced rehabilitation professionals and supported by tech partners, and its efficacy in improving function in…
- Trial name
- R@H (NCT07904624)
- Testing
- ART
- Where
- 3 sites in Singapore
- Volunteers
- 1,000 people
- Sponsor
- National University Hospital, Singapore
Epilepsy, Glioma
Blood Brain Barrier Dysfunction in Glioma and Epileptogenesis
Gliomas are the most common and deadliest primary brain tumours in children and adults. Many people with glioma also develop epilepsy, which can be difficult to treat.
- Trial name
- Bridge (NCT07909460)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University College, London
Multiple Myeloma or Plasmacytoma
Engineered Dendritic Cell Vaccines for Multiple Myeloma
The purpose of this study is to determine the feasibility, safety, and efficacy of dendritic cell (DC) vaccines in the treatment of multiple myeloma (MM) or plasmacytoma based on immune-modified DC vaccines (DCvac).
- Trial name
- NCT06435910
- Testing
- DC vaccines
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Pain
A Study Evaluating the Impact of a Painkiller Product on Quality-of-Life and Daily Functioning
The aim of this study is to generate real-world, consumer reported evidence on the perceived impact of headache relief with Panadol/Dolex on Quality of Life (QoL) and daily functioning.
- Trial name
- NCT07909590
- Testing
- Paracetamol
- Where
- Singapore
- Volunteers
- 2,100 people
- Sponsor
- HALEON
Postoperative Pain
ESP Versus SPSIP Block for Pain Relief After Shoulder Arthroscopy
This study will compare two regional anesthesia techniques for pain relief after arthroscopic shoulder surgery: high thoracic erector spinae plane (ESP) block and serratus posterior superior intercostal plane (SPSIP) block.
- Trial name
- ESP-SPSIP (NCT07906392)
- Testing
- High Thoracic Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Ischemia Stroke, TIA (Transient Ischemic Attack)
Upfront Lipid-Lowering Therapy With Statins Combined With Hybutimibe in Patients With Acute Ischemic Stroke or Transient Ischemic Attack.
This study aims to evaluate whether an upfront combination lipid-lowering therapy (statins combined with hybutimibe) can further improve the 8-week LDL-C target achievement rate (<1.8 mmol/L and ≥50% reduction from baseline)…
- Trial name
- NCT07908875
- Testing
- Atorvastatin, Hybutimibe 10mg QD
- Volunteers
- 520 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Musculoskeletal Disorders in Violinists
Effects of Scapulothoracic Stabilization Exercises in Violinists
This study aims to investigate the effects of scapulothoracic stabilization exercises on pain, muscle strength, upper extremity function, and occupational performance in individuals who play the violin.
- Trial name
- NCT07910045
- Testing
- Postural Correction and Flexibility Exercise Program, Scapulothoracic Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Hematopoietic Stem Cell Transplant
Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant
Background: Hematopoietic stem cell transplant (HSCT) is a common treatment for many cancers and other illnesses. But many people who have HSCT go on to develop liver dysfunction.
- Trial name
- NCT05722210
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Insulin Resistance, Obesity
Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity
Background: Obesity and related illnesses cause at least 2.8 million deaths each year worldwide. Few treatments exist for obesity that are safe and widely available.
- Trial name
- NCT05713799
- Testing
- Alpha-lipoic acid, Mirabegron
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Tuberculosis
Re-evaluating the Duration in Children of TB Treatment
Current tuberculosis (TB) treatment is effective (works well), but it takes a long time to cure TB. This study will evaluate if TB treatment with a higher dose of rifampicin, one of the TB medicines, and shorter TB treatment…
- Trial name
- REDUCE TB (NCT07656012)
- Testing
- Rifampicin, Isoniazid, Pyrazinamide
- Where
- Peru
- Volunteers
- 230 people
- Sponsor
- University of Wisconsin, Madison
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