Clinical trials: sponsored by Fujian Cancer Hospital
EGFR Gene Mutation
EGFR-TKIs Combine Chemotherapy as First-line Therapy for Patients With Advanced EGFR Mutation-positive NSCLC
The aim of this study was to compare the efficacy of EGFR-TKIs(Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors) treatment plus concurrent chemotherapy versus sequential treatment with EGFR-TKIs and chemotherapy in…
- Trial name
- effect (NCT02886195)
- Testing
- pemetrexed, cisplatin, Erlotinib
- Volunteers
- 120 people
- Sponsor
- Fujian Cancer Hospital
Angiogenesis, Breast Cancer
The Efficacy and Safety of Endostar Combined With Taxane-based Regimens for HER-2-negative MBC Patients
The purpose of the present study was to prospectively evaluate the efficacy and safety of endostar, a recombinant product of endostatin, combined with taxane-based regimens for HER-2 negative metastatic breast cancer (MBC)…
- Trial name
- NCT02865304
- Testing
- endostar
- Volunteers
- 80 people
- Sponsor
- Fujian Cancer Hospital
Breast Cancer
A Multicenter, Randomized Clinical Trail Evaluate Effectiveness and Security of Capecitabine or Endocrinotherapy as a Maintenance Therapy Regimen After the 1st-line Chemotherapy With Capecitabine Combine Regimen in Hormone Receptor Positive and HER2 Negative Metastatic Breast Cancer(Overstep)
A multi-sites study about the efficacy of sequential monotherapy: Capecitabine vs. endocrine therapy, in metastatic breast cancer patients with HR-positive \& HER2-negative after capecitabine-base chemotherapy.
- Trial name
- NCT02597868
- Testing
- Capecitabine, endocrine therapy
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Zhejiang Cancer Hospital
Stage IV Nasopharyngeal Carcinoma
Study of Chemotherapy Combined With Nimotuzumab in Untreated Metastatic Nasopharyngeal Carcinoma
This is an open-label, uncontrolled, multicenter phase II clinical trial. The purpose of this study is to evaluate acute toxicity and efficacy of cisplatin and 5-Fu combined with nimotuzumab in patients with untreated metastatic…
- Trial name
- NCT01616849
- Testing
- cisplatin and 5-Fu combined with nimotuzumab
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Sun Yat-sen University
Nasopharyngeal Carcinoma
Comparison the Effects of Different Neoadjuvant Chemotherapy Regimen on Acute Toxicity, Tumor Response, and Survival in Patients With Advanced Nasopharyngeal Carcinoma
The purpose of this study is to investigate the impact of different neoadjuvant chemotherapy schedules of cisplatin and 5-FU on acute toxicity, tumor response, and long-term survival in patients with advanced nasopharyngeal…
- Trial name
- NCT02500940
- Testing
- Cisplatin, Fluorouracil, Radiation therapy
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Taichung Veterans General Hospital
Esophageal Cancer
Two-field Versus Three-field Lymphadenectomy in Thoracic Esophageal Carcinoma Without Cervical Lymph Node Involvement
The purpose of this study is to compare the lymph node dissection results and prognosis in thoracic esophageal carcinoma patients without cervical lymph node involvement by preoperative CT and/or ultrasound treated by two-field…
- Trial name
- NCT02448953
- Testing
- Two-field lymphadenectomy, Three-field lymphadenectomy
- Where
- China
- Volunteers
- 786 people
- Sponsor
- Chinese Academy of Medical Sciences
Esophageal Cancer
Traditional Three-incision Esophagectomy Versus Minimally Invasive Thorascopic and Laparoscopic Esophagectomy
Esophageal carcinoma is an aggressive malignancy with poor prognosis. Surgical resection remains the most effective method for this malignant disease.
- Trial name
- NCT02448966
- Testing
- open esophagectomy, Minimally invasive esophagectomy
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Chinese Academy of Medical Sciences
Total Laparoscopic Distal Gastrectomy, Locally Advanced Gastric Cancer
Comparison of Short Term Outcomes Between Totally Laparoscopic and Laparoscopy-Assisted Distal Gastrectomy With Billroth-II Reconstruction and D2 Lymphadenectomy for Locally Advanced Gastric Cancer
Prospective Randomized Controlled Multicenter Clinical Trial for Comparison of Safety Between Totally Laparoscopic Distal Gastrectomy(TLDG) and Laparoscopy-Assisted Distal Gastrectomy(LADG) With Billroth-II Reconstruction and D2…
- Trial name
- NCT02365896
- Testing
- TLDG or LADG
- Volunteers
- 176 people
- Sponsor
- Fujian Cancer Hospital
Lung Cancer
Modified Video-assisted Thoracoscopic Surgery (VATS) Lobectomy for Early-stage Non-small Cell Lung Cancer (NSCLC)
The purpose of this study is to modify the surgical technique of VATS (video-assisted thoracoscopic surgery) lobectomy for early-stage non-small cell lung cancer.
- Trial name
- NCT01337037
- Testing
- VATS lobectomy using modified equipments, VATS lobectomy using less staples, Standard VATS lobectomy
- Where
- 14 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Peking University People's Hospital
Nasopharyngeal Cancer Recurrent
Intensity Modulated Radiotherapy in Recurrent T1-2 Nasopharyngeal Carcinoma
The hypothesis of the study is to address the efficacy and toxicity profile of aforementioned four modalities for rT1-2 NPC. Characters of the patients: list item one: 168 patients, median age 48 years (range 16-75 years） proven…
- Trial name
- NCT02113423
- Testing
- 3D-CRT, IMRT, BT, BT combined 3D-CRT or IMRT
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Fujian Cancer Hospital
Non-small Cell Lung Cancer
Curative Effect Study of Endostatin Combined With Chemoradiotherapy to Non-small-cell Lung Cancer
To evaluate the efficacy and safety of Endostar combined with concurrent chemo-radiotherapy (CCRT) in patients with unresectable stage III non-small-cell lung cancer (NSCLC).
- Trial name
- DP-EN-RT (NCT01218594)
- Testing
- Endostatin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Esophageal Cancer
Health-related Quality of Life of Patients With Esophageal Cancer After Surgery
The purpose of this multi-center prospective cohort study is to study the health-related quality of life (HRQL) together with other outcomes of patients with esophageal cancer after surgery in China.
- Trial name
- NCT01349517
- Testing
- MIE, Three-incision thoracotomy, Ivor-Lewis esophagectomy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Fudan University
Esophageal Squamous Cell Carcinoma
A Trial Estimating The Optimal Radiation Volume Of Postsurgical Radiation For Patients With Esophageal Cancer
A randomized phase II trial to estimate the optimal radiation volume of postsurgical radiation for patients with locoregionally advanced thoracic esophageal squamous cell carcinoma (T3-4, any N, M0).
- Trial name
- NCT01391572
- Testing
- enlarge irradiation volume, Small volume radiation, cisplatin
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Fudan University
Esophageal Squamous Cell Carcinoma
Is ENI Necessary For Patients With Thoracic Esophageal Cancer After Esophagectomy And With Pathological Stage Of T1-2,N+,M0
Is elective nodal irradiation (ENI) necessary for patients with thoracic esophageal cancer after esophagectomy and with pathological stage of T1-2,N+,M0?
- Trial name
- NCT01398449
- Testing
- Elective nodal irradiation (ENI), Adjuvant chemotherapy only
- Where
- China
- Volunteers
- 874 people
- Sponsor
- Fudan University
Cancer
A Study Comparing Pegylated Filgrastim and Filgrastim in Support for Chemotherapy
Neutropenia is one of the most frequent adverse effects of chemotherapy, and the main factor to limit the dosage and delay the schedule of chemotherapy.
- Trial name
- NCT01285219
- Testing
- pegylated filgrastim and filgrastim, filgrastim and pegylated filgrastim
- Volunteers
- 337 people
- Sponsor
- Chinese Academy of Medical Sciences
Nasopharyngeal Carcinoma
Study of Cetuximab in Nasopharyngeal Carcinoma (NPC) With Chemoradiotherapy
This is an open, multicenter phase Ⅱ clinical trial on cetuximab (C225) combined with IMRT + concurrent chemotherapy of cisplatin in locoregionally advanced nasopharyngeal carcinoma.
- Trial name
- ENCORE (NCT00700440)
- Testing
- C225 (cetuximab)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University