Clinical trials: not yet recruiting
Rheumatic Arthritis
Effects of Paraffin Wax Therapy and Dry Cupping on Pain and Wrist Function in Patients With Rheumatoid Arthritis
Rheumatoid arthritis is a chronic inflammatory disease that can cause pain, stiffness, and reduced functional performance in the wrist and hand joints.
- Trial name
- PDC-RA (NCT07905651)
- Testing
- Paraffin Wax Therapy, Dry cupping
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- University of Baghdad
Probiotic in Preterm Babies Use & Abuse, Uses
Probiotics in Preterm Babies Use & Abuse
This is observational study conducted at sohag univeristy hospital to asses the clinical presentation, To evaluate all aspect of using probiotics in preterm(efficacy, lowering of sepsis, lowering necrotizing enterocolitis…
- Conditions
- Probiotic in Preterm Babies Use & Abuse, Uses, Side Effect
- Trial name
- Pro-pre-bab (NCT07910344)
- Testing
- Probiotic
- Volunteers
- 200 people
- Sponsor
- Norhan Mohamed Abdelrady
Post Operative Pain, Emergence Agitation
Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Ultrasound-Guided Sphenopalatine Ganglion Block for Functional Endoscopic Sinus Surgery
This prospective, randomized, double-blind, controlled trial will compare the efficacy and safety of dexmedetomidine versus dexamethasone as adjuvants to bupivacaine in ultrasound-guided bilateral sphenopalatine ganglion block…
- Conditions
- Post Operative Pain, Emergence Agitation, Functional Endoscopic Sinus Surgery
- Trial name
- NCT07911202
- Testing
- Bupivacaine & normal saline, Dexmedetomidine & Bupivacaine., Dexamethasone & Bupivacaine.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Missing Tooth/Teeth
S-TiUltra Implant Study
This prospective clinical study will compare early healing and implant stability between two Nobel Biocare dental implant systems, NobelReplace S-TiUltra and NobelReplace CC TiUnite.
- Trial name
- NCT07911319
- Testing
- NobelReplace S-TiUltra, NobelReplace TiUnite
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Maryland, Baltimore
Malignant Neoplastic Disease (Disorder)
Saruparib in HRDsig+ Solid Tumors
The main purpose of this study is to study the effect of saruparib, an experimental PARP inhibitor, on tumors that have an Homologous Recombination Deficiency Signature (HRDsig) positive tumor by the investigational…
- Trial name
- NCT07832630
- Testing
- Saruparib, FoundationOne®CDx
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Bladder Carcinoma, Prostate Carcinoma
Remote Screening and Navigation to Increase Trial Enrollment, INVITE Trial
This clinical trial studies the feasibility, acceptability, appropriateness, and effectiveness of a remote screening and navigation program in increasing clinical trial enrollment among patients with prostate and bladder cancer…
- Trial name
- INVITE (NCT07908407)
- Testing
- Electronic Health Record Review, Patient Navigation, Prescreen
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Fred Hutchinson Cancer Center
Osteoarthritis, Knee
Boosting Exercise Adherence in Knee Osteoarthritis
This project, conducted within the Department of Veterans Affairs Healthcare System (VHA), will test the effectiveness of an intervention to improve adherence to home exercise among Veterans receiving physical therapy (PT) for…
- Trial name
- BOOST-OA (NCT07219732)
- Testing
- Usual PT Care (UC), BOOST-OA
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- VA Office of Research and Development
Catheter Ablation, Radiofrequency
Early Ambulation Safety Evaluation, Ultrasound-guided Percutaneous Venous Closure
The purpose of this study is to evaluate whether patients can safely walk sooner after catheter-based heart procedures when the VASCADE MVP or VASCADE MVP XL vascular closure device is used.
- Trial name
- NCT07910227
- Testing
- VASCADE MVP and MVP XL
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pennsylvania
Autoimmune Diseases
CAR-T Cells Targeting Autoimmune Diseases
The purpose of this study is to assess the feasibility, safety and efficacy of CAR-T cell therapy in patients with autoimmune disease.
- Trial name
- NCT05459870
- Testing
- 4SCAR T cells
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
Alcohol Problems, Post-Traumatic Stress Disorder
The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans
Veterans seeking to improve their romantic relationships when high conflict and unhealthy dynamics (e.g., aggression) are present remain underserved within the VHA with few treatment options.
- Trial name
- ACT-SHARE (NCT06746727)
- Testing
- Acceptance and Commitment Therapy for Social Health, Achievement, and Relationship Effectiveness (ACT-SHARE)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Dry Eye
a Novel siRNA Eyedrops for DED Treatment
A single-center, randomized, double-blind, placebo-controlled, cross-over clinical trial designed to evaluate the effectiveness and safety of a novel siRNA eye drops for the treatment of dry eye syndrome
- Trial name
- NCT07908251
- Testing
- Low dose Arm, High dose Arm
- Volunteers
- 30 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Fibromyalgia
Toward Biomarker-Guided Fibromyalgia Treatment With Non-Invasive Vagus Nerve Stimulation
Fibromyalgia is a syndrome with clinical symptoms that affect multiple systems of the body. Although basic science research and clinical research trials have been carried out, the cause and the mechanism of fibromyalgia are still…
- Trial name
- R61VNS (NCT07904351)
- Testing
- Transcutaneous Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Massachusetts General Hospital
Early-stage Breast Cancer, Fear of Cancer Recurrence
Psilocybin FCR Early-Stage Breast Cancer
This trial is designed to evaluate efficacy and psychological mechanisms of single-dose psilocybin-assisted psychotherapy (PAP) to treat fear of cancer recurrence (FCR), psychiatric (anxiety, depression) distress and…
- Conditions
- Early-stage Breast Cancer, Fear of Cancer Recurrence, Anxiety, Depression
- Trial name
- NCT07909408
- Testing
- Psilocybin 25 mg, Psilocybin 5 mg
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Spinal Cord Injury
Influence of Transcranial Electrical Stimulation on Arm and Hand Function After Cervical Spinal Cord Injury
The goal of this pilot study is to find out how four different types of transcranial electrical stimulation (tES) affect brain activity, the process of acquiring new skills (also called motor learning), and hand function after…
- Trial name
- NCT07909317
- Testing
- transcranial direct current stimulation (tDCS) + FTP, transcranial pulsed current stimulation (tPCS) + FTP, transcranial random noise stimulation (tRNS) + FTP
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shepherd Center, Atlanta GA
Myopia, Astigmatism
The EYERISING Study
The purpose of this clinical trial is to see if and how well Repeated Low-Level Red Light (RLRL) therapy works to control myopia over 12 months.
- Conditions
- Myopia, Astigmatism, Anisometropia
- Trial name
- NCT07909720
- Testing
- Repeated Low-Level Red Light (RLRL) therapy
- Where
- 2 sites in United States, Nepal
- Volunteers
- 333 people
- Sponsor
- University of Wisconsin, Madison
Acute Respiratory Tract Infection
HAIQU (Hospital AIr QUality)
The purpose of this research is to assess whether integration of an aerosol biosensor and air quality risk assessment software that integrates into a building management system will improve indoor air quality metrics in hospital…
- Trial name
- HAIQU (NCT07670117)
- Testing
- Self-swab test
- Where
- 3 sites in United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Multiple Myeloma, Plasmacytoma
Frontline Combination CAR-T Cell Therapy for Multiple Myeloma or Plasmacytoma
The aim of this clinical trial is to assess the feasibility, safety, and efficacy of CAR-T cell therapy targeting multiple cancer cell antigens in high-risk multiple myeloma or plasmacytoma as part of a frontline treatment…
- Trial name
- NCT06429150
- Testing
- CAR-T cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
High-risk Myeloid Malignancy, Allogenic Stem Cell Transplantation
Maintenance Treatment With Imetelstat in Patients With High-Risk Myeloid Neoplasms After Allo-SCT
The purpose of this clinical trial is to learn if imetelstat is safe to use in participants with high-risk myeloid malignancies who have received an allogenic hematologic stem cell transplantation (allo-SCT).
- Conditions
- High-risk Myeloid Malignancy, Allogenic Stem Cell Transplantation, Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML)
- Trial name
- NCT07909733
- Testing
- imetelstat
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Wisconsin, Madison
Total Knee Arthroplasty, Knee Osteoarthristis
Application of Perinatal Derivatives in Total Knee Arthroplasty
This pilot study investigators whether the use of perinatal derivatives during knee replacement, in the form of an injection around the joint and patch over the knee joint incision, improves patient outcomes (including…
- Trial name
- NCT07908342
- Testing
- Intraoperative application of CTM Flow and CTM Thick, Total knee arthroplasty (TKA)
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Walking Mesh
Smart Sock for Monitoring Walking and Supporting Physical Activity in Older Adults
The goal of this randomized feasibility clinical trial is to learn whether a low-cost smart sock and mobile application can be used safely, reliably, and comfortably to support gradual walking activity in adults aged 60 years and…
- Trial name
- NCT07902102
- Testing
- Low-Cost Smart Sock and Older-Adult Mobile Application, Standard Individual Walking Plan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Malaya
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