Clinical trials: sponsored by Alcon Research
Cataract
Clinical Study of a Fluid Accommodating Intraocular Lens (IOL) Design
The purpose of this clinical study is to evaluate the surgical, refractive, and visual outcomes with implantation of an investigational intraocular lens (IOL).
- Trial name
- NCT05317728
- Testing
- BAL-FAIOL IOL, Monofocal IOL, Cataract surgery
- Where
- 6 sites in Costa Rica, Dominican Republic and 2 more
- Volunteers
- 175 people
- Sponsor
- Alcon Research
Dry Eye Symptoms
Comparison of Ocular Lubricants in People With Symptoms of Dry Eye
Ocular dryness and discomfort are symptoms commonly associated with dry eye. Lubricating eye drops, also called artificial tears, are often used to moisten the eye and provide relief from these symptoms.
- Trial name
- SPHINX (NCT07451184)
- Testing
- Propylene glycol 0.6%, 3% trehalose and 0.15% sodium hyaluronate
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Waterloo
Neovascular Age-related Macular Degeneration (nAMD)
Study of AR-14034 in Participants With Neovascular Age-Related Macular Degeneration (nAMD)
The primary purpose of this study is to evaluate the safety and durability of single- and repeat administration of AR-14034 Sustained Release (SR) in subjects with neovascular age-related macular degeneration (nAMD).
- Trial name
- NOVA-1 (NCT05769153)
- Testing
- AR-14034 SR implant lower dose, AR-14034 SR implant higher dose, AR-14034 SR implant
- Where
- 42 sites in United States
- Volunteers
- 139 people
- Sponsor
- Alcon Research
Glaucoma, Open Angle, MIGS
Three Year Outcomes of Combined Hydrus Microstent With iTrack Canaloplasty
The goal of this study is to learn if combining minimally invasive glaucoma surgery (MIGS) procedures with different mechanisms of action increases the effectiveness of MIGS.
- Conditions
- Glaucoma, Open Angle, MIGS, Minimally Invasive Glaucoma Surgery, Canaloplasty
- Trial name
- NCT07073937
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Refractive Errors
Clinical Investigation of a Femtosecond Laser for Corneal Flap Creation
The purpose of this study is to see how safe the WaveLight Ultraviolet Femtosecond Laser, Model 1026 (UV fs-Laser), is for creating corneal flaps during laser-assisted in situ keratomileusis (LASIK) surgery.
- Trial name
- NCT07036835
- Testing
- LASIK Surgery, UV fs-Laser, IR fs-Laser
- Where
- Australia
- Volunteers
- 128 people
- Sponsor
- Alcon Research
Refractive Errors, Myopia
Evaluation of Delefilcon A Contact Lenses
The purpose of the study is to evaluate the lens fit characteristics of delefilcon A contact lenses with different base curves and diameters.
- Trial name
- NCT06884202
- Testing
- Delefilcon A contact lenses with different base curves and diameters, Delefilcon A contact lenses with standard base curves and diameters
- Where
- 16 sites in United States
- Volunteers
- 267 people
- Sponsor
- Alcon Research
Cataract, High Myopia
3D Visualization System in Highly Myopic Cataract Operation
This study aims to investigate the impact of depth of field differences between the use of the 3D imaging system (NGENUITY® 3D Visualization System, Alcon, TX, USA) and conventional optical microscope in cataract surgery for…
- Trial name
- 3D-HiMCO (NCT06264830)
- Testing
- Alcon-NGENUITY®(NG)-system, Standard cataract operation
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Dry Eye Disease (DED)
SYSTANE® PRO vs. MIEBO™ in Dry Eye Disease
This is a prospective, randomized, double-masked, multi-site clinical trial designed to compare the efficacy of SYSTANE® PRO (Alcon Laboratories, Inc.) to MIEBO™ (Bausch + Lomb) in treating symptoms of evaporative dry eye disease…
- Trial name
- NCT07243275
- Testing
- SYSTANE® PRO, MIEBO™ (Perfluorohexyloctane, PFHO)
- Where
- 4 sites in United States
- Volunteers
- 269 people
- Sponsor
- Indiana University
Dry Eye Disease
An Evaluation of the Safety and Tolerability of Ocular Lubricants
The purpose of this study is to evaluate the safety and tolerability of two new artificial tear formulations in subjects with moderate dry eye disease.
- Trial name
- NCT07238699
- Testing
- FID123440 test formulation, FID123437 test formulation
- Where
- 4 sites in Australia
- Volunteers
- 124 people
- Sponsor
- Alcon Research
Aphakia, Corneal Astigmatism
Clareon Toric Study (T2-T9)
The purpose of this post-market study is to describe the long-term safety and performance of Clareon Toric Intraocular Lenses (IOLs).
- Trial name
- NCT06285695
- Testing
- Clareon Toric IOL, Cataract surgery
- Where
- 6 sites in Canada
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Astigmatism
Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)
The purpose of this study is to generate clinical data to quantify the impact of residual astigmatism on the overall visual performance during distance, intermediate, and near viewing in patients implanted with Clareon Vivity…
- Trial name
- NCT06784063
- Testing
- Clareon Vivity Extended Vision IOL
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Cataract, Lenses, Intraocular
Effect of Intraocular Lens (IOL) Centration and Tilt on Visual Performance With Clareon® Vivity® IOL Implantation
The goal of this observational study is to assess the effect of intraocular lens (IOL) movement in patients who have undergone Clareon® Vivity® IOL implantation.
- Trial name
- NCT05827133
- Testing
- No intervention
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- East Coast Institute for Research
Ocular Hypertension, Suspect Glaucoma
Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects
The goal of this clinical trial is to compare participants treated with latanoprost to those treated with Rocklatan (netarsudil/latanoprost) to determine whether the addition of netarsudil results in greater improvements in…
- Trial name
- NCT04401982
- Testing
- Rocklatan (Netarsudil 0.02%/ latanoprost 0.005), Latanoprost (0.005%)
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, Baltimore
Cataract and IOL Surgery
Comparing Visual Outcomes in Matched Patients Receiving a Low Cylinder Power Toric IOL or a Non-toric IOL
The purpose of the study is to determine if visual function is improved with implantation of a low-cylinder toric intraocular lens, relative to a non-toric intraocular lens.
- Trial name
- NCT06717607
- Testing
- low cylinder toric IOL, non-toric IOL implantation
- Where
- Norway
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ifocus Oyeklinikk
Contact Lens Comfort and Successful Refitting, Presbyopia
Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses
The purpose of this study is to determine the comfort and vision of DAILIES TOTAL1 Multifocal contact lenses in a population of satisfied INFUSE One-Day Multifocal contact lens wearers
- Trial name
- INFUSETODT1 (NCT07638943)
- Testing
- DAILIES TOTAL1 Multifocal (delefilcon A)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gordon Schanzlin New Vision
Glaucoma, Ocular Hypertension
Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension
This study evaluates the effects of netarsudil (Rhopressa) on the trabecular meshwork in subjects with ocular hypertension or open-angle glaucoma.
- Trial name
- NCT07588152
- Testing
- Netarsudil Ophthalmic Solution (Rhopressa), Artificial Tears (AT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana University
Primary Open Angle Glaucoma or Ocular Hypertension
Effect of Rhopressa on Intraocular Pressure (IOP) in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension Post-SLT
The purpose of this study is to collect data about how Rhopressa affects IOP in patients who have had an SLT procedure in both eyes.
- Trial name
- NCT06865144
- Testing
- Netarsudil ophthalmic solution 0.02%, Artificial tears
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- East Coast Institute for Research
Astigmatism Bilateral
Evaluation of Wear Experience With a Weekly Replacement Soft Contact Lens in Neophyte Lens Wearers With Astigmatism
This open-label study is of adults with astigmatism who have never worn contact lenses. Subjects will be fit into a one week planned-replacement contact lenses and will wear lenses for approximately 3 weeks.
- Trial name
- NCT06751225
- Testing
- One week replacement soft contact lenses
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study B
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06401551
- Testing
- CPO Pro IOL, CPO IOL, Cataract Surgery
- Where
- 8 sites in United States
- Volunteers
- 71 people
- Sponsor
- Alcon Research
Aberration, Corneal Wavefront
Immediate Effects of Lipid-Based and Non-Lipid Artificial Tears on Corneal Aberrations
This study evaluates the immediate effects of two types of artificial tear formulations on corneal aberrations in a healthy population.
- Trial name
- ILEACT (NCT06784661)
- Testing
- Lipid-Based Artificial Tear, Non-Lipid Artificial Tear
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Seville