Clinical trials: sponsored by Tempus AI
Solid Tumor, Adult, Solid Tumor
A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
The goal of this study is to test A2B530,an autologous logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorectal cancer (CRC), pancreatic cancer (PANC), non-small cell lung cancer (NSCLC), and other…
- Conditions
- Solid Tumor, Adult, Solid Tumor, Pancreatic Cancer, Pancreatic Neoplasms
- Trial name
- EVEREST-1 (NCT05736731)
- Testing
- A2B530, xT-Onco with HLA-LOH Assay
- Where
- 8 sites in United States
- Volunteers
- 160 people
- Sponsor
- A2 Biotherapeutics Inc.
Breast Cancer
Gut and Tumor Microbiome in Patients With Early Stage (II-III), Locally Advanced or Advanced ER-positive and HER2-negative Breast Cancer.
The purpose of this research study is to collect samples of blood and stool and analyse primary tumor from participants with breast cancer to see how the bacteria in the body affect cancer and how well it responds to treatment.
- Trial name
- NCT06126003
- Testing
- Observation
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- BioCorteX Inc
Atrial Fibrillation, Structural Heart Disease
Electrocardiogram-based Artificial Intelligence-assisted Detection of Heart Disease
Atrial fibrillation is an abnormal beating of the heart that can lead to stroke or heart failure. Structural heart diseases are conditions that affect the heart valves or heart muscle and can cause permanent heart damage if left…
- Trial name
- ECG-AID (NCT05442203)
- Testing
- Zio Patch Monitor, Echocardiogram
- Where
- 3 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Tempus AI
Hepatitis C
Pegylated Interferon and Ribavirin Therapy in Chronic Hepatitis Genotype 4
Genotype 4 is the least-studied hepatitis C virus genotype and was considered a difficult to treat genotype due to the disappointing response of chronic hepatitis C genotype 4 to conventional interferon monotherapy.
- Trial name
- NCT00277862
- Testing
- Pegylated IFN- alpha 2b, Ribavirin
- Where
- 4 sites in Egypt
- Volunteers
- 280 people
- Sponsor
- Ain Shams University
Hepatitis C
Timing and Duration of Acute Hepatitis C Treatment
Spontaneous resolution of acute hepatitis C infection cannot be predicted and the majority of cases persist and become chronic. This randomized trial assesses the efficacy and safety of peginterferon alfa-2b.
- Trial name
- NCT00241618
- Testing
- Pegylated interferon alpha 2, Ribavirin
- Where
- 3 sites in Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University