Clinical trials: sponsored by Tulane University
Hypertension, Blood Pressure
Caribbean and South America Team-based Strategy to Control Hypertension
The CATCH cluster randomized trial will test the effectiveness and implementation outcomes of implementing and scaling up the 2017 American Heart Association and 2021 World Health Organization hypertension guidelines through a…
- Trial name
- CATCH (NCT05405920)
- Testing
- Team-based Care to Implement Single-Pill Combination Therapy, Enhanced Usual Care
- Where
- 2 sites in Colombia, Jamaica
- Volunteers
- 1,706 people
- Sponsor
- Tulane University
Heart Diseases
Health Electronic Assessment of Risks and Trends Using Biometric Equipment and Technology
This is a phase 0, non-interventional, longitudinal, electronic data capture (EDC) study to facilitate the HEARTBEAT Study project has set out to explore the potential use of smartwatches in collecting and analyzing biometric…
- Trial name
- HEARTBEAT (NCT06753045)
- Testing
- Smartwatch
- Where
- 3 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Tulane University
Resistant Hypertension
The RESPLASH Study
To assess the safety and effectiveness of renal artery denervation with subsequent splanchnic nerves denervation via catheter-based radiofrequency ablation in improving blood pressure and glycemic control in patients with…
- Trial name
- NCT06880562
- Testing
- Splanchnic Nerve Denervation, Renal Denervation Only
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Tulane University
Anxiety Disorders, Anxiety State
Intergenerational Study of War-Affected Youth
War-related violence is a leading driver of mental disorders and illness affecting children in low- and middle-income countries (LMICs).
- Conditions
- Anxiety Disorders, Anxiety State, Depressive Disorder, Mood Disorders
- Trial name
- ISWAY (NCT06440460)
- Where
- Sierra Leone
- Volunteers
- 804 people
- Sponsor
- Boston College
Chlamydia, Gonorrhea
A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities
This study includes testing for four STIs (chlamydia, gonorrhea, syphilis, and HIV) at no cost. If positive, individual subjects will also be counseled and offered options for treatment for themselves and their sex partners that…
- Conditions
- Chlamydia, Gonorrhea, Hiv, Syphilis
- Trial name
- NCT06428643
- Testing
- Chlamydia, gonorrhea, syphilis, and HIV screening
- Where
- United States
- Volunteers
- 2,322 people, healthy volunteers welcome
- Sponsor
- Tulane University
Dental Caries in Children
Water From Bottles to Establish Strong Teeth
The waterBEST study is a proof-of-concept, randomized, double-masked, placebo controlled, parallel group study evaluating dental caries-preventive effects of fluoridated bottled water compared to non-fluoridated bottled water in…
- Trial name
- waterBEST (NCT04893681)
- Testing
- Fluoridated bottled drinking water, Non-fluoridated drinking water
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Maternal Health Care, Hypertensive Disorder of Pregnancy
Implementation Models for Blood Pressure Monitoring in Pregnancy and Postpartum: Connected MOM Plus
Quality improvement (QI) initiative to improve uptake and utilization of Connected MOM, particularly among those with limited access to health care
- Trial name
- NCT07691541
- Testing
- Connected MOM +
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Tulane University
Diabetes Type 2, Insomnia
Enhancing Diabetes Care by Treating Insomnia
Insomnia is highly prevalent in individuals with type 2 diabetes (T2D) and is associated with poor glycemic control. Louisiana has one of the highest diabetes prevalence rates in the U.S., with significant disparities by race…
- Trial name
- NCT07062406
- Testing
- Cognitive Behavioral Therapy for Insomnia, Usual care for diabetes management, Usual care for treatment of insomnia
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tulane University
Substance Use Disorders, Chronic Pain
IMPOWR-ME Project 1: Trial of Yoga and Physical Therapy Onsite at Opioid Treatment Programs
This is a pragmatic, open label, randomized controlled trial with 1:1:1 allocation to 12 weeks of: (1) onsite yoga at opioid treatment programs (OTPs), (2) onsite physical therapy (PT) at OTPs, or (3) treatment as usual (TAU).
- Conditions
- Substance Use Disorders, Chronic Pain, Opioid Use Disorder, Back Pain Lower Back Chronic
- Trial name
- NCT05492825
- Testing
- Yoga, Physical Therapy, Treatment As Usual
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Albert Einstein College of Medicine
Obesity
Collaborative Multi-level Obesity Intervention Engaging Communities Trial
The goal of this clinical trial is to test the effectiveness of an evidence-based multi-level intervention for weight loss and the feasibility, fidelity, and sustainability of implementing the intervention in people living with…
- Trial name
- CONNECT (NCT06835686)
- Testing
- Health Literacy and Culturally Tailored Materials, Community-Engaged Health Coaching and Navigation, Self-Monitoring and Remote Patient Monitoring of weight and physical activity
- Where
- 18 sites in United States
- Volunteers
- 522 people
- Sponsor
- Tulane University
HIV/AIDS
Community Health Workers And MHealth to ImProve Viral Suppression Plus (CHAMPS+)
Although global efforts have been made to end the HIV epidemic, there are still some gaps in HIV testing, antiretroviral therapy (ART) adherence, and viral suppression (VS) among people with HIV (PWH).
- Trial name
- CHAMPS+ (NCT06472206)
- Testing
- CHW Sessions, CleverCap
- Where
- 5 sites in United States
- Volunteers
- 420 people
- Sponsor
- Columbia University
Sexual Violence, Intimate Partner Violence (IPV)
Evaluation of State-Level Sexual and Gender Minority Laws for the Primary Prevention of Sexual and Intimate Partner Violence Among Sexual and Gender Minority Youth in the U.S.
The goal of this observational study is to learn how state-level laws related to sexual and gender minority (SGM) youth affect the risk of sexual violence (SV) and intimate partner violence (IPV) among sexual minority (SM) youth…
- Trial name
- YAP (NCT07729644)
- Testing
- Enumerated anti-bullying state legislation, Conversion therapy state legislation, Gender-affirming care state legislation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Berkeley
Congenital Disorders of Glycosylation
Clinical and Basic Investigations Into Congenital Disorders of Glycosylation
The purpose of this research is to study the natural history of congenital disorders of glycosylation and its causes and treatments.
- Trial name
- NCT04199000
- Where
- 12 sites in United States
- Volunteers
- 500 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Human Papilloma Virus Related Cervical Carcinoma
The Women's Screening and Self-Testing Program (PROMETA) Study
This proposal directly addresses the ability to safely scale-up a Screen-Triage-Treat approach to cervical cancer screening. The investigators propose to capitalize on a pool of screen-eligible women accessing routine care within…
- Trial name
- PROMETA (NCT06810739)
- Testing
- HPV DNA testing be self-collected vaginal swab
- Where
- Mozambique
- Volunteers
- 8,445 people
- Sponsor
- Tulane University
Opioid-use Disorder, Chronic Pain
Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment
The proposed IMPOWR Research Center at Montefiore-Einstein (IMPOWR-ME) will create a multidisciplinary and synergistic program of research to test multimodal treatments that address both chronic pain and opioid use disorder.
- Trial name
- NCT05039554
- Testing
- Acceptance and commitment therapy, Valera Smartphone Application, Treatment as Usual
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Albert Einstein College of Medicine
Chlamydia Females, Gonorrhea Female
A Randomized Controlled Trial of Doxycycline Post Exposure Prophylaxis to Prevent Incident Bacterial STIs Among Women in the United States
The bacterial sexually transmitted infections (STIs) chlamydia, gonorrhea, and syphilis cause multiple adverse outcomes in women, and prevention strategies are critically needed.
- Conditions
- Chlamydia Females, Gonorrhea Female, Syphilis Female, Adherence
- Trial name
- NCT07704957
- Testing
- Doxycycline, Standard of Care (SOC)
- Volunteers
- 519 people
- Sponsor
- Tulane University
Atrial Fibrillation, Atrial Arrhythmia
Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The study aims to evaluate and compare the incidence of atrial arrhythmias (including Post-Operative Atrial Fibrillation (POAF), atrial flutter, and atrial tachycardia) stratified by baseline Utah fibrosis stages and overall…
- Conditions
- Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
- Trial name
- NCT05014802
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Atrial Fibrillation, Obstructive Sleep Apnea
Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study
The investigators hypothesize that Obstructive Sleep Apnea (OSA) is an independent risk factor for atrial fibrosis development. The investigators aim to prove the presence of atrial fibrosis on Delayed Enhancement Magnetic…
- Trial name
- NCT04814420
- Testing
- Delayed enhancement magnetic resonance imaging (DE-MRI)
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tulane University
Blood Pressure
Potassium Intake-response Trial to Control Hypertension
The Potassium Intake-response Trial to Control Hypertension (PITCH) will test the intake-response relationship between potassium supplementation and blood pressure, which may inform clinical guidelines on the optimal level of…
- Trial name
- PITCH (NCT05758142)
- Testing
- Potassium Chloride
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Tulane University
Ebola Virus Disease
REVIVE (Response to the Ebola Virus Vaccine)
This study is a vaccine-related clinical trial which will be conducted by our study team at Kenema Government Hospital (KGH)'s Viral Hemorrhagic Fever Program in collaboration with Tulane University School of Medicine.
- Trial name
- NCT05992480
- Testing
- rVSVDG-ZEBOV-GP Ebola Virus Vaccine (ERVEBO)
- Where
- Sierra Leone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tulane University