Clinical trials: active, not recruiting
Healthy, 24-Hour Movement Guidelines
A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers
The goal of this clinical trial is to evaluate whether a home-based mHealth intervention can improve adherence to the 24-Hour Movement Guidelines in preschool-aged children (3-4 years old) who currently meet 0 or 1 of the…
- Conditions
- Healthy, 24-Hour Movement Guidelines, Feasibility Studies, Sleep
- Trial name
- Shining Star (NCT06667661)
- Testing
- Shining Star mHealth App
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Breast Cancer, Lymphoma
Assessment of Cognitive Function in Breast Cancer and Lymphoma Patients Receiving Chemotherapy
Cognitive impairments in cancer patients represent an important clinical problem. Studies to date estimating prevalence of difficulties in memory, executive function, and attention deficits have been limited by small sample sizes…
- Trial name
- CANTAB (NCT01382082)
- Where
- 29 sites in United States
- Volunteers
- 1,432 people, healthy volunteers welcome
- Sponsor
- University of Rochester NCORP Research Base
Sleep Disorder, Polycystic Ovarian Syndrome (PCOS)
Association Between Polycystic Ovary Syndrome and Sleep Quality: A Questionnaire-Based Study
This cross-sectional study enrolled 310 women with PCOS (Rotterdam criteria) at a tertiary referral center between September 2025 and January 2026.
- Trial name
- PMOS (NCT07898423)
- Where
- Turkey (Türkiye)
- Volunteers
- 290 people
- Sponsor
- Tepecik Training and Research Hospital
Atypical Endometrial Hyperplasia, Stage I Uterine Corpus Cancer AJCC v7
Levonorgestrel-Releasing Intrauterine System in Treating Patients With Complex Atypical Hyperplasia or Grade I Endometrial Cancer
This phase II trial studies how well levonorgestrel-releasing intrauterine system works in treating patients with complex atypical hyperplasia or grade I endometrial cancer.
- Conditions
- Atypical Endometrial Hyperplasia, Stage I Uterine Corpus Cancer AJCC v7, Stage IA Uterine Corpus Cancer AJCC v7, Stage IB Uterine Corpus Cancer AJCC v7
- Trial name
- NCT00788671
- Testing
- Laboratory Biomarker Analysis, Levonorgestrel-Releasing Intrauterine System, Quality-of-Life Assessment
- Where
- 7 sites in United States
- Volunteers
- 69 people
- Sponsor
- M.D. Anderson Cancer Center
Glioblastoma, Gliosarcoma
Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
This randomized phase II/III trial studies how well temozolomide and veliparib work compared to temozolomide alone in treating patients with newly diagnosed glioblastoma multiforme.
- Trial name
- NCT02152982
- Testing
- Laboratory Biomarker Analysis, Quality-of-Life Assessment, Temozolomide
- Where
- 391 sites in United States, Puerto Rico
- Volunteers
- 447 people
- Sponsor
- National Cancer Institute (NCI)
Subarachnoid Hemorrhage
Auricular VNS Following Subarachnoid Hemorrhage
This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following spontaneous subarachnoid hemorrhage.
- Trial name
- NCT04557618
- Testing
- Auricular Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Anna Huguenard
Puberty, Precocious
First Observatory of Precocious Puberty.
The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe.
- Trial name
- PAPPEL (NCT06263868)
- Where
- 23 sites in France
- Volunteers
- 3,360 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Tricuspid Valve Regurgitation, Heart Valve Diseases
TRISCEND JAPAN Study
A prospective, open, non-randomized, multicenter, clinical trial to evaluate the safety and effectiveness of the Edwards EWJ-202 transcatheter tricuspid valve replacement system in the treatment of patients with at least severe…
- Conditions
- Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases
- Trial name
- TRISCEND JAPAN (NCT05760989)
- Testing
- Edwards EWJ-202 Transcatheter Tricuspid Valve Replacement System
- Where
- 8 sites in Japan
- Volunteers
- 53 people
- Sponsor
- Edwards Lifesciences
Multiple Sclerosis (MS) - Relapsing-remitting
Tai Chi Training for Persons With Multiple Sclerosis.
Tai Chi combines strength and neuromuscular training with diaphragmatic breathing, attention, imagery and relaxation. After an initial learning period, participants can practise independently, potentially supporting self-efficacy…
- Trial name
- NCT07890974
- Testing
- Tai Chi training
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Karolinska Institutet
Diabetic Macular Edema, Diabetic Retinopathy
Long-Term Follow-up Study of ADVM-022 in DME (INFINITY-EXT)
This is a prospective, observational study designed to evaluate the long-term safety and tolerability of ADVM-022 in participants with diabetic macular edema (DME).
- Trial name
- NCT05607810
- Testing
- ADVM-022
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 22 people
- Sponsor
- Adverum Biotechnologies, Inc.
Prostate Cancer
The BARCODE 1 Pilot Study
BARCODE 1 is a screening study designed to investigate the role of genetic profiling for targeting population prostate cancer screening. This study forms a pilot of 300 men, with the view to continue to a future study of 5000 men.
- Trial name
- BARCODE1Pilot (NCT03158922)
- Testing
- Genetic SNP profiling, Prostate cancer screening, Prostate biopsy
- Where
- United Kingdom
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Breast Cancer Invasive, Hormone-receptor-positive Breast Cancer
Neoadjuvant Pyrotinib in HR-positive and HER2-low High-risk Early Breast Cancer
This is a multi-center, open-lable, prospective, randomized phase III clinical trial to further validate the efficacy and safety of neoadjuvant pyrotinib combined with chemotherapy in HR-positive/HER2-low (IHC 2+/FISH-negative)…
- Conditions
- Breast Cancer Invasive, Hormone-receptor-positive Breast Cancer, HER2 Low Breast Carcinoma, Early-stage Breast Cancer
- Trial name
- NCT06144944
- Testing
- Pyrotinib, epirubicin or doxorubicin, cyclophosphamide, paclitaxel, Epirubicin or doxorubicin, cyclophosphamide, paclitaxel
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Adolescent Idiopathic Scoliosis (AIS)
Construction of a Screening and Precision Intervention System for Adolescent Idiopathic Scoliosis Based on the DIERS Spinal Moiré System
Taking the DIERS Spinal Moiré System as the primary tool, this study intends to establish an early warning model for adolescent scoliosis based on the system, verify the quantitative relationship between different body postures…
- Trial name
- NCT07899294
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Jiawei Jiang
Paroxysmal AF
FARAPULSE™ Pulsed Field Ablation System
To obtain real world data on the use of, and provide continued evidence on safety and effectiveness of the FARAPULSE™ Pulsed Field Ablation (PFA) system when used per hospitals' standard of care in Chinese population.
- Trial name
- NCT06762717
- Testing
- FARAPULSE™ Pulsed Field Ablation system
- Where
- China
- Volunteers
- 501 people
- Sponsor
- Boston Scientific Corporation
Maternity Nursing, Obstetric Nursing
Enhancing Male Nursing Students' Competence in Maternity Care: A Quasi-Experimental Study in Egypt
The primary aim of this study is to evaluate the effect of structured clinical teaching scenarios on male nursing students' competence-including knowledge, self-confidence, and practical performance-in maternity care.
- Conditions
- Maternity Nursing, Obstetric Nursing, Clinical Competence, Simulation Training
- Trial name
- NCT07894419
- Testing
- Structured Scenario-Based Clinical Teaching in Maternity Care
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Idiopathic Pulmonary Fibrosis
A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment
This study is open to adults who are at least 40 years old and have idiopathic pulmonary fibrosis (IPF). People can participate in the study if they have a forced vital capacity (FVC) greater than or equal to 45% of the predicted…
- Trial name
- NCT07036523
- Testing
- BI 765423
- Where
- 46 sites in United States, Australia and 8 more
- Volunteers
- 81 people
- Sponsor
- Boehringer Ingelheim
Healthy Participants
A Study to Evaluate the Pharmacokinetic Characteristics of HS-20118 Under Different Dosing Conditions in Healthy Participants
This study is a single-center, open-label, randomized, four-period dosing clinical study designed to evaluate the pharmacokinetic characteristics of HS-20118 under different dosing conditions in healthy participants.
- Trial name
- HS-20118-111 (NCT07896915)
- Testing
- HS-20118
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Women Over 40 Years of Age in the Perimenopausal or Menopausal Stage, Presenting With Associated Symptoms
Relaxation Techniques and Pilates for Menopause Symptoms
Primary objective: To evaluate the effectiveness of relaxation techniques combined with the Pilates method versus the Pilates method alone in improving perimenopausal and menopausal symptoms.
- Trial name
- NCT07897812
- Testing
- Pilates
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Belen Díaz Pulido
Bipolar Disorder
Functional Remediation for Older Adults With Bipolar Disorder
Bipolar Disorder (BD) is a chronic and severe mental illness characterized by the emergence of alternating mood episodes which range from extreme depression to manic states.
- Trial name
- FROA-BD (NCT05186337)
- Testing
- FROA-BD programme
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Prostate Cancer
Phase 2 Clinical Trial of 177Lu-P17-088 for mAPMR Prostate Cancer
PSMA is an ideal target for precision diagnosis and treatment of prostate cancer. P17-088 is a novel albumin-binding PSMA-targeted radioligand.
- Trial name
- NCT07562438
- Testing
- 177Lu-P17-088
- Where
- China
- Volunteers
- 25 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University