Clinical trials: completed
Child, Anaphylaxis
Observation Periods and Biphasic Reaction Risk Factors in Pediatric Emergency Anaphylaxis Cases
This study reviews the medical records of children who presented to the pediatric emergency department of Adnan Menderes University Hospital with a diagnosis of anaphylaxis between January 2014 and December 2024.
- Conditions
- Child, Anaphylaxis, Pediatric Emergency Care, Biphasic Anaphylactic Reaction
- Trial name
- NCT07231393
- Volunteers
- 67 people
- Sponsor
- Aydin Adnan Menderes University
Breast Cancer, Breast Cancer Screening
Instagram and Podcast Intervention for Breast Cancer Awareness and Screening
Breast cancer is the most common cancer among women worldwide. This randomized controlled trial aims to evaluate the effect of an Instagram- and podcast-based intervention on women's breast cancer awareness, health beliefs, and…
- Trial name
- NCT07673588
- Testing
- Instagram-Based Breast Cancer Awareness Intervention, Instagram-Podcast-Based Breast Cancer Awareness Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Ankara University
Lumbar Disc Herniation, Low Back Pain
Comparison Of Early Mobilization And Electrical Stimulation On Functional Recovery After Lumbar Disc Herniation Surgery
This randomized controlled trial aims to compare the effectiveness of early mobilization alone versus early mobilization combined with electrical stimulation on functional recovery following lumbar disc herniation surgery.
- Conditions
- Lumbar Disc Herniation, Low Back Pain, Postoperative Rehabilitation
- Trial name
- EMES-LDH (NCT07575477)
- Testing
- Early Mobilization Program, Electrical Stimulation (NMES/TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Diabetes Mellitus, Type 2, Influenza
Information-Based Interventions for Influenza Vaccination Among Older Adults With Diabetes in Yangzhou, China
Influenza can cause serious illness in older adults, particularly those with diabetes. Although influenza vaccination is an important preventive measure, vaccination uptake among older adults in China remains low.
- Trial name
- NCT07901673
- Testing
- Standard Information Intervention, Gain-Framed Information Intervention, Loss-Framed Information Intervention
- Where
- 4 sites in China
- Volunteers
- 759 people
- Sponsor
- Southeast University, China
Vibration, Lumbar Disc Herniation
IASTM and Vibration Effects on Pain, Functionality, and Kinesiophobia in Lumbar Disc Herniation
The aim of this study is to investigate the effects of Instrument-Assisted Soft Tissue Mobilization and vibration massage therapy on pain, functionality, and kinesiophobia in individuals with lumbar disc herniation.
- Conditions
- Vibration, Lumbar Disc Herniation, Soft Tissue Mobilization
- Trial name
- NCT07293676
- Testing
- Exercise, IASTM, Percussion massage therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Depression, Anxiety
Game-Based Digital Intervention for Depression in Adolescents
The goal of this clinical trial is to evaluate the effectiveness of digital interventions in treating depression and anxiety in adolescents.
- Trial name
- NCT06778785
- Testing
- Digital Intervention, Health Education, Personalization Algorithm
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Healthy Volunteers
Phase 1 Clinical Study of MWN109 Injection in Healthy Chinese Volunteers
This is a randomized, double-blind, placebo-controlled, single- and multiple- dose-escalating Phase 1a study. The objective is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of MWN109…
- Trial name
- NCT07787624
- Testing
- MWN109
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Linperlisib, PRCA
Low-Dose Linperlisib Achieves Rapid Hematological Response in a Patient With Pure Red Cell Aplasia and Moderate-to-Severe Renal Insufficiency: A Case Report
This article reports a case of a 70-year-old male patient diagnosed with T-cell large granular lymphocytic leukemia (T-LGLL)-associated pure red cell aplasia (PRCA) complicated by moderate-to-severe renal insufficiency.
- Conditions
- Linperlisib, PRCA, Moderate-to-Severe Renal Insufficiency
- Trial name
- NCT07900282
- Testing
- linperlisib
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Peking Union Medical College Hospital
Atrial Fibrillation
High-Intensity Aerobic Lifelong Training--AF
This study is a single-center RCT. Potential subjects with symptomatic non-permanent AF will be enrolled to determine the effect of sprint interval training (SIT) in comparison to moderate-intensity continuous training (MICT) and…
- Trial name
- HALT-AF (NCT03241433)
- Testing
- High intensity interval training, Moderate intensity continuous training, No Exercise
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Minnesota
Preoperative Sedation
A Trial of Dexmedetomidine Hydrochloride Nasal Spray in Preoperative Sedation of Adults
The study is being conducted to evaluate the efficacy and safety of dexmedetomidine hydrochloride nasal spray for preoperative sedation in adults.
- Trial name
- NCT04383418
- Testing
- dexmedetomidine hydrochloride nasal spray, dexmedetomidine hydrochloride nasal spray blank preparation
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Lassa Fever, Lassa Virus Infection
Lassa Fever Clinical Course and Prognostic Factors in Nigeria
The investigators propose to conduct a nationwide (Nigeria), prospective, non-interventional cohort study describing the clinical course, biological characteristics, case management and outcomes in patients hospitalized for a…
- Conditions
- Lassa Fever, Lassa Virus Infection, Pregnancy Complications, Acute Kidney Injury
- Trial name
- LASCOPE (NCT03655561)
- Testing
- Non interventional research
- Where
- 2 sites in Nigeria
- Volunteers
- 1,100 people
- Sponsor
- Alliance for International Medical Action
Mild Cognitive Impairment (MCI)
Feasibility Study of 'SuperBrain BOOM' for Mild Cognitive Impairment Patients
The goal of this clinical trial is to learn whether a mobile-based personalized physical activity program called SuperBrain BOOM is safe and works to improve cognitive function, physical performance, mood, and quality of life in…
- Trial name
- SuperBrainBOOM (NCT07101380)
- Testing
- Tablet-based Physical SuperBrain BOOM, Smartphone-based SuperBrain BOOM
- Where
- 4 sites in South Korea
- Volunteers
- 45 people
- Sponsor
- Ajou University School of Medicine
Stroke, Transient Ischemic Attack
Reducing Stroke Risk in African-American Men
The project is a 6-month prospective Randomized Controlled Trial evaluating the effects of TargEted MAnageMent Intervention (TEAM, N=80) vs.
- Trial name
- TEAM2 (NCT04402125)
- Testing
- TargEted MAnageMent Intervention (TEAM)
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Case Western Reserve University
HIV Infections, Opioid Use
Evaluation of Neuroinflammation FNOS PET/CT in HIV (+) and (-) Subjects With OUD and Healthy Controls
The purpose of this research is to measure the extent of inflammation in the brain between different groups of participants using a radioactive tracer called [18F]NOS.
- Trial name
- NCT04401917
- Testing
- [18F]NOS
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Foot Ulcers, Diabetic, Plantar Foot Pressure
Plantar Load Analysis of Neuropathic and Neuroischaemic Diabetes-Related Foot Ulceration
This single-centre observational case-control study investigates how peripheral arterial disease influences plantar load in people with diabetes who have recently healed a plantar foot ulcer.
- Conditions
- Foot Ulcers, Diabetic, Plantar Foot Pressure, Fat Pad Atrophy, Peripheral Arterial Disease
- Trial name
- PLANE-DFU (NCT07901478)
- Testing
- Pedar™ In-Shoe Plantar Pressure Measurement System, STAMPS 3D Digital Image Correlation System, Weight-Bearing Ultrasound of the Plantar Fat Pad
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Asthma
A Study to Evaluate Solriktug in Adult Participants With Asthma
Phase 2 study to evaluate the safety, tolerability, PK, immunogenicity, and pharmacodynamics of solriktug with adult participants with asthma.
- Trial name
- RAINIER (NCT06496607)
- Testing
- NSI-8226
- Where
- 69 sites in United States
- Volunteers
- 145 people
- Sponsor
- Uniquity One (UNI)
Oncology, Infections
A Comparison of Static and Dynamic PET/CT (HYPOTHESIS Generation Study)
The general purpose of this initial study is to evaluate whether parametric PET/CT improves diagnosis and treatment monitoring in select diseases. The specific aim of the HYPOTHESIS GENERATION study is: 1.
- Conditions
- Oncology, Infections, Inflammation
- Trial name
- NCT05110443
- Testing
- D-WB PET/CT
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Aarhus University Hospital
Benign Prostatic Hyperplasia (BPH)
To Linguistically and Psychometrically Validate the Hong Kong Chinese Version of the BPH 3-item Questionnaire
This study is to linguistically and psychometrically validate the translated and culturally adapted Hong Kong Chinese version of the BPH 3-item questionnaire.
- Trial name
- NCT05785286
- Testing
- BPH 3-item questionnaire
- Where
- 2 sites in Hong Kong
- Volunteers
- 66 people
- Sponsor
- Chinese University of Hong Kong
Postoperative Pain Following Coronary Artery Bypass Grafting (CABG)
Combined SPSP and TTP Blocks for Postoperative Analgesia Post-CABG
The goal of this clinical trial is to learn if combining two ultrasound-guided nerve blocks - one for the front of the chest and one for the side of the chest - works better than standard pain medications alone to treat pain…
- Trial name
- PACT (NCT07658521)
- Testing
- Transversus Thoracic Plane Block, Transversus Thoracic Plane (TTP) Block, Conventional Systemic Analgesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Empowering Mothers
Empowering First-Time Mothers
This randomized controlled trial aims to evaluate the effect of digital lactation nursing support on breastfeeding achievement and maternal-infant outcomes among first-time mothers.
- Trial name
- Empowering (NCT07900932)
- Testing
- digital lactation nursing support program
- Where
- 2 sites in Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University