Clinical trials: Phase not applicable, open to volunteers
Rotator Cuff Tendonitis
Effects of Cervicothoracic Mobilization in Patients With Supraspinatus Tendinitis
This study aims to evaluate the effects of cervicothoracic junction mobilization on pain, shoulder range of motion (ROM), and disability in patients with supraspinatus tendinitis.
- Trial name
- NCT07921017
- Testing
- Cervicothoracic Junction Mobilization, Traditional Physical Therapy
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Riphah International University
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This study evaluates whether a wearable near-infrared autofluorescence (NIRAF) imaging system can help surgeons identify and preserve parathyroid glands during thyroid surgery.
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Chronic Low-back Pain (cLBP), High-Impact Chronic Pain (HICP)
Comparing Non-Medicine Strategies for Improving Low Back Pain
The goal of this clinical trial is to help veterans manage high-impact chronic pain (HICP) in the lower back. The trial will use a program, ENCompaSS (Education, Navigated Care, and Supported Self-Management) designed to reduce…
- Trial name
- NCT07679178
- Testing
- ENCompaSS (Education, Navigated Care, and Supported Self-Management) with VA Stepped Usual Care
- Where
- United States
- Volunteers
- 530 people
- Sponsor
- Duke University
End Stage Renal Disease (ESRD), Kidney Transplant
Hypothermic Kidney Machine Perfusion With Omnisol
Insufficient availability of organs from brain dead (DBD) and living donors has necessitated increased use of less than optimal organs from donation after cardiac death (DCD) or from extended criteria donors.
- Conditions
- End Stage Renal Disease (ESRD), Kidney Transplant, Kidney Failure, Renal and Urinary Tract Therapeutic Procedures
- Trial name
- OMNIPUMP (NCT07920926)
- Testing
- Omnisol organ preservation solution
- Volunteers
- 16 people
- Sponsor
- Vivalyx GmbH
Spinal Cord Injuries, Tetraplegia
MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury
The purpose of this study is to develop and test the hardware and software components of the MyHand-SCI device to assist with hand function for individuals with C6-C7 spinal cord injury.
- Trial name
- NCT05553457
- Testing
- Testing of MyHand-SCI Device
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Columbia University
Breast Cancer
Decision Support for Chemoprevention
The purpose of this study is to find out whether electronic tools that provide information and reminders to people at high risk for breast cancer and their healthcare providers can increase the use of medications, such as…
- Trial name
- NCT07899151
- Testing
- RealRisks Decision Aid
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Columbia University
Acute Respiratory Infection
Expanded Diagnostic Strategy in Older Adults Hospitalized With Community-Acquired Acute Respiratory Infection
This study will evaluate whether an expanded diagnostic strategy can reduce antibiotic use in patients aged 65 years or older who are hospitalized with community-acquired acute respiratory infection, without negatively affecting…
- Trial name
- NeuBluMul (NCT07883902)
- Testing
- Expanded Diagnostic Strategy, Conventional Diagnostic Strategy
- Where
- Spain
- Volunteers
- 406 people
- Sponsor
- Santiago Lopez Gil
Colonoscopy
Effect of Box Breathing Exercise on Anxiety, Pain, and Pulmonary Function Tests in Patients Undergoing Colonoscopy
This study is a prospective, randomized controlled clinical trial designed to determine the effect of box breathing exercises on anxiety, pain, and pulmonary function in patients undergoing colonoscopy.
- Trial name
- NCT07728890
- Testing
- box breathing exercises
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Constipation, Abdominal Pain
Effects of a Prebiotic-Probiotic Combination on Constipation Symptoms and Quality of Life
This study aims to evaluate whether a combination of a prebiotic (1-kestose) and a probiotic (Lacticaseibacillus rhamnosus BBH112) improves gastrointestinal symptoms and quality of life in adults with constipation-related…
- Conditions
- Constipation, Abdominal Pain, Abdominal Bloating, Abdominal Discomfort
- Trial name
- NCT07923279
- Testing
- Lacticaseibacillus rhamnosus BBH112, 1-Kestose (GF2)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
People Who Use Opioids/People With Opioid Use Disorder (OUD)
Prescribe to Prevent HIV: A Hybrid Trial Helping Addiction Clinics Prevent HIV & Infections Through Safer Drug Use Support
In the U.S., an estimated 3.6 million people who inject drugs (PWID) face a growing yet preventable health crisis, with rising cases of serious injection-related infections (SIRI), including HIV, due to limited access to two…
- Trial name
- P2PH (NCT07073924)
- Testing
- Implementation strategy bundle
- Where
- 4 sites in United States
- Volunteers
- 536 people
- Sponsor
- University of Pittsburgh
Apnea of Prematurity
nCPAP-NAVA-Backup Versus Standard nCPAP for Severe Apnea in Preterm Infants ≤28 Weeks
The goal of this clinical trial is to determine whether nasal continuous positive airway pressure (nCPAP) with neurally adjusted ventilatory assist (NAVA) backup ventilation (nCPAP-NAVA-backup mode) reduces the rate of severe…
- Trial name
- NAVAPNEA (NCT07923604)
- Testing
- nCPAP-NAVA-backup mode, nCPAP mode
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University Hospital, Geneva
Histamine, Cowhage
Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity
In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep deprivation on itch: To investigate similarity and differences between itch and pain by comparing the effect of sleep…
- Conditions
- Histamine, Cowhage, Sleep Deprivation
- Trial name
- NCT06081998
- Testing
- Histamine, Cowhage
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Congenital Heart Disease (CHD)
Autologous Thymus Transplant in Children With Congenital Heart Disease: A Pilot Study
This pilot study will look at whether putting back a child's own thymus tissue during heart surgery is safe and may help support the immune system in children with congenital heart disease (CHD).
- Trial name
- ATTT (NCT07799259)
- Testing
- Autologous Thymus Transplant
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cerebral Palsy
Sensory Integration Therapy vs Conventional Physical Therapy in Children With Mixed Cerebral Palsy
The study aims to compare Sensory Integration Therapy (SIT) with Conventional Physical Therapy (CPT) for improving gross motor function in children aged 4-10 years with mixed cerebral palsy.
- Trial name
- NCT07921069
- Testing
- Sensory Integration Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Chronic Kidney Diseases
An Individuation Intervention to Reduce Socioeconomic Disparities in Chronic Kidney Disease Care
The goal of this clinical trial is to test whether an individuation intervention can improve the quality of chronic kidney disease (CKD) care for patients with low socioeconomic status (SES) and to understand the mechanisms…
- Trial name
- NCT07921342
- Testing
- Individuation + Implicit Bias Training, Implicit Bias Training Alone
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Brigham and Women's Hospital
Knee Osteoarthritis (Knee OA)
Holistic Healing for Knee Osteoarthritis
This study is a single-center, three-arm, open-label randomized controlled trial designed to compare the effectiveness of integrated care, standard medical care, and Ayurvedic care in adults with early knee osteoarthritis…
- Trial name
- HEAL-KOA (NCT07768709)
- Testing
- Trayodashang Guggulu, Ashwagandha Churna, Janubasti
- Where
- India
- Volunteers
- 300 people
- Sponsor
- All India Institute of Medical Sciences, Jodhpur
Amyotrophic Lateral Sclerosis (ALS), Bacillus Coagulans
A Study on the Addition of Alsum30 for the Treatment of Amyotrophic Lateral Sclerosis
This single-center, open-label pilot study will enroll approximately 15 adults with amyotrophic lateral sclerosis (ALS) to assess the safety and tolerability of adding Alsum30 to their care.
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Bacillus Coagulans, Dietary Supplement, Sulforaphane
- Trial name
- NCT07922031
- Testing
- Sulforaphane and Bacillus coagulans GBI-30, 6086
- Volunteers
- 15 people
- Sponsor
- Liu Qing
Prostate Cancer, Urinary Incontinence
Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment
This study is being done at Duke Health and includes adult men who have been treated for localized prostate cancer. The goal is to see if it is feasible and acceptable to offer sex therapy by telehealth after prostate cancer…
- Conditions
- Prostate Cancer, Urinary Incontinence, Erectile Dysfunction
- Trial name
- RESTORE-PC (NCT07685249)
- Testing
- Sex Therapy, Pelvic Floor Physical Therapy, Vacuum Erection Device (VED)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University
HIV, HIV Treatment
Evaluating the Impact of Using the B-OK Bottles for HIV and ART Literacy in South Africa
Consistent use of antiretroviral therapy (ART) is essential for achieving suppression among people with HIV (PWH). Yet despite improvements in access to ART and improving viral suppression rates, an estimated one-third of PWH…
- Trial name
- NCT07703891
- Testing
- B-OK Bead Bottles Intervention (delivered in person), B-OK Bottles Intervention (delivered by video), Control
- Where
- South Africa
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Subarachnoid Aneurysm Hemorrhage
Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Despite its lower incidence rate within the stroke population and tendency to affect younger individuals, SAH carries the highest risk of PSCI.
- Trial name
- NCT07588997
- Testing
- early motor-cognitive integrated training (e-MCIT), Early mobilization
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
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