Clinical trials: sponsored by Florida State University
Healthy
The Effects of External Nasal Dilator Strips on Sleep and Cardiovascular Health
The goal of this interventional study is to learn if wearing an external nasal dilator strip while sleeping changes objective and perceived sleep quality, immediate post-waking blood pressure, and immediate-post waking heart rate…
- Trial name
- NCT06403098
- Testing
- External Nasal Dilator Strip
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Hypertension (HTN), Chronic Stress
Dual-Language B-MORE for Hypertension
This pilot study is a single-arm clinical feasibility trial evaluating the feasibility, acceptability, and preliminary efficacy of a brief adaptation of Mindfulness-Oriented Recovery Enhancement (B-MORE) for reducing stress and…
- Trial name
- NCT07623031
- Testing
- Behavioral: B-MORE (Brief Mindfulness-Oriented Recovery Enhancement)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida State University
Major Depressive Disorder, Anhedonia
Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression
Anhedonia, the inability to seek-out and experience pleasure, is a common symptom in depression that predicts treatment-resistance and is sometimes exacerbated by first-line antidepressants.
- Trial name
- DBA (NCT06132581)
- Testing
- Delta-beta tACS via the Neurocare Direct Current Stimulator Multi-Channel 4, Theta-gamma tACS via the Neurocare Direct Current Stimulator Multi-Channel 4
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Florida State University
HIV
SHARE Project Define
The overall goal of the current study is to define modifiable intervention targets that are developmentally- and culturally-relevant in pathways between cumulative stress and self-management outcomes - alcohol use and HIV - among…
- Trial name
- NCT06125509
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Florida State University
Executive Dysfunction
Causal Role of the Aperiodic Signal for Working Memory
Working memory (WM) is the ability to hold relevant information in mind in the absence of sensory input. The capacity for WM is a foundation for cognitive control and higher cognitive function more broadly.
- Trial name
- TRAS (NCT06126809)
- Testing
- Steep-tRAS, Flat-tRAS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Stress Disorders, Traumatic, Stress Disorders, Traumatic, Acute
Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration
The investigators are conducting a randomized controlled trial to assess the impact of Resiliency in Stressful Experiences (RISE) - a comprehensive trauma-based program for young men releasing from a southeastern state's prisons.
- Conditions
- Stress Disorders, Traumatic, Stress Disorders, Traumatic, Acute, Depressive Symptoms, Anxiety
- Trial name
- NCT04785677
- Testing
- Resiliency in Stressful Experiences (RISE) Program
- Where
- United States
- Volunteers
- 403 people
- Sponsor
- Florida State University
PTSD - Post Traumatic Stress Disorder, TBI-Traumatic Brain Injury
Adaptation of the STAIR-NT for First Responders
This study is a randomized controlled pilot examining the implementation of an adapted intervention, Skills Training in Affective and Interpersonal Regulation-Narrative Therapy (STAIR-NT), among a first responder population with…
- Trial name
- NCT07212140
- Testing
- Adapted STAIR-NT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Florida State University
ADHD
Evaluating the Efficacy of Central Executive Training (CET) For Young Children With ADHD
Initial non-randomized trial of behavioral parent training (BPT) compared to central executive training (CET), followed by a randomized controlled trial of CET+BPT for young children with ADHD.
- Trial name
- NCT07784348
- Testing
- Central executive training, Behavioral parent training
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Florida State University
Medical Cannabis
Medical Marijuana and Open Road Driving Task
Medical marijuana use among adults 50 and older has more than doubled in the past decade with exponential increases projected in this demographic by 2050, and prescription opioids are one of the most common treatments for pain…
- Trial name
- ROADACE (NCT06995937)
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Florida State University
Neuroendocrine Tumors, Gastroenteropancreatic Neuroendocrine Tumor
Neuroendocrine Tumors - Patient Reported Outcomes
With so many therapeutic options available (i.e.: biologic therapy, liver directed therapy, radiotherapy and chemotherapy), the purpose of this project is to partner with patients on comparative effectiveness research (CER) to…
- Conditions
- Neuroendocrine Tumors, Gastroenteropancreatic Neuroendocrine Tumor, Lung Neuroendocrine Neoplasm, Neuroendocrine Carcinoma
- Trial name
- NET-PRO (NCT05064150)
- Where
- 14 sites in United States
- Volunteers
- 2,539 people
- Sponsor
- University of Iowa
Attention Deficit Hyperactivity Disorder
Interventions for English Language Learners At-Risk for ADHD
The goal of this clinical trial is to compare the effect of language and behavioral interventions for students who are English language learners and who have symptoms of attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT05918991
- Testing
- Daily Report Card, Language Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Florida International University
Post Traumatic Stress Disorder
Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD
The purpose of this study is to examine the benefits of combining repetitive Transcranial Magnetic Stimulation (rTMS) coupled with Cognitive Processing Therapy (CPT) in treating combat-related Posttraumatic Stress Disorder (PTSD)…
- Trial name
- NCT03932773
- Testing
- Active rTMS, Cognitive Processing Therapy
- Where
- 3 sites in United States
- Volunteers
- 330 people
- Sponsor
- The University of Texas at Dallas
Diabetes Mellitus, Type 2
Feasibility Testing an Exercise Program to Improve Cognition for T2DM Patients
This proposed study will advance science by providing evidence on the feasibility of a standardized, rigorously designed and delivered exercise program to improve cognition and plasma brain-derived neurotrophic factor (BDNF)…
- Trial name
- NCT04590833
- Testing
- Supervised walking on a treadmill, Supervised stretching exercise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Florida State University
Bisexuality, Homosexuality
Skills to Empower Affirmative Men
Participants are Vietnamese national. Over the course of the study activities, approximately 184 self-identified Vietnamese national gay and bisexual men ages 18 and above living in HCMC, Viet Nam, as well as 10 key informants…
- Conditions
- Bisexuality, Homosexuality, HIV Infections
- Trial name
- VINA STEAM (NCT05732675)
- Testing
- "VINA STEAM" (Skills to Empower Affirmative Men)
- Where
- Vietnam
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Florida State University
Cardiovascular Diseases, Dysphagia
Clinical Markers of Dysphagia in Cardiac Surgical Patients
Although dysphagia is a known complication of cardiac surgery, risk factors and sensitive bedside clinical markers of dysphagia have not yet been identified.
- Trial name
- NCT05304416
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, Simultaneous FEES and Videofluoroscopy instrumental swallowing exam, Videofluoroscopy instrumental swallowing exam (VFSS)
- Where
- 2 sites in United States
- Volunteers
- 347 people
- Sponsor
- University of Florida
Cannabis Use Disorder, Severe
Impact of Cannabis Use and Abstinence on Emotion
The goal of this experimental study is to test how three weeks of cannabis abstinence impacts threat and reward processing in females with Cannabis Use Disorder.
- Trial name
- ICAE (NCT07746440)
- Testing
- Contingency management for cannabis abstinence and lab visit attendance, Contingency management for lab visit attendance
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Florida State University
Parkinson Disease, Multiple System Atrophy, Parkinson Variant
Automated Imaging Differentiation of Parkinsonism
The purpose of this study is to test the performance of the AID-P across 21 sites in the Parkinson Study Group. Each site will perform imaging, clinical scales, diagnosis, and will upload the data to the web-based software tool.
- Conditions
- Parkinson Disease, Multiple System Atrophy, Parkinson Variant, Progressive Supranuclear Palsy
- Trial name
- AIDP (NCT05913687)
- Testing
- AIDP
- Where
- 21 sites in United States, Canada
- Volunteers
- 315 people
- Sponsor
- University of Florida
Pain
Brief Mindfulness Intervention for Patients at a Free Acute Care Clinic
This is a single-site, two-arm, parallel-group randomized clinical trial (RCT). The clinical effects of a 4-minute audio-recorded mindfulness intervention for 100 English-speaking patients and 100 Spanish-speaking patients at a…
- Trial name
- NCT07025161
- Testing
- Pain Coping Information, Mindful Pain Management
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Florida State University
PTSD, Post Traumatic Stress Disorder
Feasibility of a Digital Therapeutic for Adults With Posttraumatic Stress Disorder (PTSD)
This study is exploring the efficacy of a digital therapeutic app in reducing symptoms of posttraumatic stress disorder (PTSD) in adults.
- Trial name
- NCT06868446
- Testing
- OTX-601 Digital Therapeutic - Version 1, OTX-601 Digital Therapeutic - Version 2, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oui Therapeutics, Inc.
Mechanistic Self-Dehumanization Condition, Control Condition
Inducing Self-Dehumanization to Examine Oxytocin and Suicide Risk
The goal of this experiment is to further determine if self-dehumanization is a novel risk factor for suicide. This study will induce self-dehumanization using a novel experimental self-dehumanized future condition (i.e., a…
- Trial name
- NCT06710964
- Testing
- The Ten Item Personality Inventory, Mechanistic Self-Dehumanization Condition, Debrief
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florida State University