Clinical trials: sponsored by Fujian Cancer Hospital
Nasopharyngeal Cancinoma (NPC), Radiation-induced Oral Mucositis
Prevention and Treatment of Radiation-Induced Oral Mucositis in NPC With Houyanqing Oral Liquid
To explore the efficacy of Houyanqing Oral Liquid combined with conventional treatment in preventing and treating radiation-induced oral mucositis, so as to improve the quality of life of nasopharyngeal carcinoma patients…
- Trial name
- NCT07311772
- Testing
- Houyanqing Oral Liquid, Conventional Treatment for Radiation-Induced Oral Mucositis
- Where
- 16 sites in China
- Volunteers
- 386 people
- Sponsor
- Sun Yat-sen University
Nasopharyngeal Cancinoma (NPC)
International Collaborative Study on AJCC/UICC TNM-10 for Nasopharyngeal Cancer
The goal of this international, multicenter, prospective observational study is to improve prognostication and prediction of failure pattern for nasopharyngeal carcinoma (NPC), in order to provide more accurate guidance for…
- Trial name
- NCT07013461
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- The University of Hong Kong-Shenzhen Hospital
Advanced Malignant Solid Tumor
PRL3-Zumab in Patients With Advanced Solid Tumors
This is a multicenter, Phase II, open-label, single-dose-level (6 mg/kg) study of PRL3-zumab monotherapy in patients with unresectable or metastatic solid tumors.
- Trial name
- China Phase II (NCT07541001)
- Testing
- PRL3-ZUMAB
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Intra-IMMUSG Pte Ltd
Stage IIB-III NSCLC, Sleeve Lobectomy
RATS Sleeve Lobectomy After Neo-Chemo-IO for NSCLC
The goal of this multicenter prospective observational study is to learn about the surgical difficulty and outcomes of robotic-assisted sleeve lobectomy in patients with non-small cell lung cancer (NSCLC) after neoadjuvant…
- Conditions
- Stage IIB-III NSCLC, Sleeve Lobectomy, Robotic Surgery, Neoadjuvant Chemoimmunotherapy
- Trial name
- RIDDLE-NSCLC (NCT07541521)
- Testing
- Robot-assisted thoracoscopic surgery (RATS) sleeve lobectomy
- Where
- 10 sites in China, France and 1 more
- Volunteers
- 100 people
- Sponsor
- Shanghai Chest Hospital
Gastric Cancer (GC), Gastric Adenocarcinoma
Laparoscopic Staging for Stage III Gastric Cancer
This study aims to determine, through a multicenter randomized controlled design, the impact of precision treatment guided by laparoscopic staging on overall survival (OS), surgical conversion rate, and peritoneal metastasis rate…
- Trial name
- CGCA202501 (NCT07533825)
- Testing
- Laparoscopic Staging-Guided Therapy, Without Laparoscopic Exploration
- Where
- China
- Volunteers
- 968 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Neoadjuvant Chemoimmunotherapy, Robotic Pulmonary Resection
Downstaging and RATS After Neo-Chemo-IO: Impact on Surgical Outcomes in NSCLC
The goal of this observational study is to learn whether tumor and nodal downstaging after neoadjuvant chemo-immunotherapy is associated with better surgical outcomes in patients with clinical stage IIB-III non-small cell lung…
- Conditions
- Neoadjuvant Chemoimmunotherapy, Robotic Pulmonary Resection, Stage IIB-III NSCLC
- Trial name
- DRAGON-NSCLC (NCT07528066)
- Testing
- Robotic-assisted surgery (RATS)
- Where
- 10 sites in China, France and 1 more
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Rectal Neoplasms
Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer
Given the growing focus on preserving organ function and the utilization of neoadjuvant therapy, it is important to investigate and enhance the application of comprehensive neoadjuvant therapy in low rectal cancer.
- Trial name
- NCT06417476
- Testing
- Short-course radiotherapy, Irinotecan, Oxaliplatin
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Pei-Rong Ding
Surgical Procedure, Unspecified, Prostate Cancer
Posterior Extra-fascial RARP in Intermediate or High Risk Prostate Cancer
This study was designed as a prospective, multicentre, double-blind, randomised controlled clinical trial. It aims to investigate the feasibility and safety of the posterior approach extrafascial technique and the anterior…
- Trial name
- NCT06434649
- Testing
- Extrafascial robotic assisted radical prostatectomy via posterior approach, Extrafascial robotic assisted radical prostatectomy via anterior approach
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Ning Xu
Cervical Cancer
SKB264 Plus QL1706 in Recurrent or Metastatic Cervical Cancer
This study is a prospective, single arm II clinical trial. The main objective of the study is to evaluate the efficacy and safety of the combination of Sacituzumab Tirumotecan (SKB264) and QL1706 in the treatment of recurrent or…
- Trial name
- NCT07256236
- Testing
- Sacituzumab tirumotecan, QL1706
- Where
- 14 sites in China
- Volunteers
- 89 people
- Sponsor
- Fujian Cancer Hospital
Vaginitis, Radiotherapy Induced Mucositis
Clinical Study on the Prevention and Treatment of Radiation Vaginitis With Triethanolamine Cream
The objective of this clinical trial is to understand whether triethanolamine cream can prevent and treat acute radiation vaginitis. It will also learn about the safety of triethanolamine cream.
- Trial name
- NCT07492654
- Testing
- Trolamine (Biafine)
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Fujian Cancer Hospital
Nasopharyngeal Carcinoma
Chidamide in Combination With Toripalimab and Anlotinib in Recurrent/Metastatic Nasopharyngeal Carcinoma.
To explore and evaluate the dose-limiting toxicity (DLT) profile of the fixed-dose combination of toripalimab, anlotinib, and chidamide in patients with recurrent/metastatic nasopharyngeal carcinoma (R/M NPC), and to determine…
- Trial name
- NCT07320963
- Testing
- Chidamide, Toripalimab, Anlotinib
- Volunteers
- 52 people
- Sponsor
- Sun Yat-sen University
Nasopharyngeal Carcinoma (NPC)
Becotatug Vedotin Plus Sintilimab in Locoregionally Advanced NPC
This study is a multicenter, randomized, controlled phase III clinical trial aiming to investigate the efficacy and safety of Becotatug Vedotin induction therapy followed by concurrent chemoradiotherapy (CCRT) combined with…
- Trial name
- NCT07459296
- Testing
- Becotatug Vedotin, Sintilimab, Cisplatin
- Where
- China
- Volunteers
- 266 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Breast Cancer
Dalpiciclib Combined With Endocrine Therapy and Metronomic Capecitabine vs Dalpiciclib Combined With Endocrine Therapy for First-line Treatment
This study is an open-label, multicenter, randomized controlled study. It is planned to include 258 patients with HR +/HER2- advanced breast cancer with visceral metastases.
- Trial name
- NCT07467330
- Testing
- dalpiciclib + capecitabine + endocrine therapy, dalpiciclib + endocrine therapy
- Where
- China
- Volunteers
- 258 people
- Sponsor
- Fujian Cancer Hospital
Locally Advanced Rectal Cancer With Liver Metastases
SCRT(Short Course Radiotherapy) Combined With CAPOX Plus QL1706 for Rectal Cancer Liver Metastases
To enhance the treatment efficacy of rectal cancer liver metastasis through a multidisciplinary approach of radiotherapy, immunotherapy, and chemotherapy, and to provide a new direction for the combination treatment strategy.
- Trial name
- NCT06787183
- Testing
- Short course radiotherapy, Capecitabine, Oxaliplatin
- Where
- 2 sites in China
- Volunteers
- 42 people
- Sponsor
- Fujian Cancer Hospital
Advanced Leiomyosarcoma
A Trial for Advanced Leiomyosarcoma With Human Organoid-guided Personalized Efficacy
This study is a prospective single arm multicenter intervention study aimed at evaluating the feasibility of using organoid drug sensitivity results to guide first-line treatment of advanced leiomyosarcoma.
- Trial name
- LMS-HOPE (NCT07405346)
- Testing
- treatment based on the results of drug sensitivity analysis
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Oral Tongue Squamous Cell Carcinoma
Postoperative Radiotherapy for Early-stage Oral Tongue Squamous Cell Carcinoma Patients With Risk Factors: a Prospective, Multicenter, Randomized Controlled, Open-labelled Trial
The goal of this clinical trial is to learn whether postoperative radiotherapy can delay disease recurrence in patients with early-stage oral squamous cell carcinoma who have high-risk factors.
- Trial name
- PORT-ESTER (NCT07402525)
- Testing
- Postoperative radiotherapy
- Where
- 28 sites in China
- Volunteers
- 190 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Nasopharyngeal Carcinoma
CROSSROAD: Treatment Regimen Switch - Re-induction Chemotherapy vs. Direct Radiotherapy in LANPC With Inadequate Response to Induction Chemotherapy
This study aims to compare the efficacy of two treatment strategies-re-induction chemotherapy followed by radiotherapy versus direct radiotherapy-in patients with locally advanced nasopharyngeal carcinoma (LANPC) who did not…
- Trial name
- NCT07399158
- Volunteers
- 223 people
- Sponsor
- Fujian Cancer Hospital
Thymic Epithelial Tumor
Intrathoracic Chemotherapy for TETs With Pleural Spread or Recurrence (CHOICE-2)
Hyperthermic intrathoracic chemotherapy (HITOC) offers a strategy to eliminate microscopic residual disease after surgical resection.
- Trial name
- NCT07383142
- Testing
- Surgery alone, Surgery+HITOC
- Where
- China
- Volunteers
- 202 people
- Sponsor
- Shanghai Zhongshan Hospital
Locally Advanced Nasopharyngeal Carcinoma
Timing Optimization of Immunotherapy During Neoadjuvant Chemotherapy for Locally Advanced Nasopharyngeal Carcinoma
This is a multicenter, open-label, randomized phase II clinical trial designed to evaluate the optimal timing of toripalimab administration during neoadjuvant chemotherapy in patients with locoregionally advanced nasopharyngeal…
- Trial name
- NCT07388836
- Testing
- Toripalimab
- Volunteers
- 198 people
- Sponsor
- Fujian Cancer Hospital
Nasopharyngeal Cancinoma (NPC), Intensity-modulated Radiotherapy
IMRT Alone for Stage IB Nasopharyngeal Carcinoma Without High-Risk Features
This observational study aims to evaluate the efficacy and safety of intensity-modulated radiotherapy (IMRT) alone in patients with stage IB nasopharyngeal carcinoma (NPC) without high-risk features.
- Conditions
- Nasopharyngeal Cancinoma (NPC), Intensity-modulated Radiotherapy, Stage IB
- Trial name
- NCT07376603
- Testing
- IMRT along
- Where
- China
- Volunteers
- 169 people
- Sponsor
- Qiaojuan Guo