Clinical trials: sponsored by Medtronic - MITG
Lung Neoplasms, Cancer of Lung
MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s)
Does lung ablation improve clinical outcomes for patients deemed to be surgically high-risk?
- Conditions
- Lung Neoplasms, Cancer of Lung, Cancer of the Lung, Lung Cancer
- Trial name
- MARK 1A (NCT02673021)
- Testing
- Microwave ablation
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Anesthesia
Bispectral Index and End-Tidal Anesthetic Gas Concentration in Pediatric Patients
The purpose of this study is to investigate the relationship between BIS™ values including EEG profile and anesthetic agents in the pediatric population
- Trial name
- BTIGER (NCT04810481)
- Testing
- BIS Complete Monitoring System
- Where
- 8 sites in United States
- Volunteers
- 209 people
- Sponsor
- Medtronic - MITG
Anesthesia
Evaluation of Bispectral Index (BIS™) and Levels of Sedation With Common Inhalational Anesthetics in Healthy Volunteers (OLIVER)
To investigate the relationship between BIS™ and inhaled anesthetics across a wide range of anesthetic concentration and hypnotic states, and to provide evidence to support BIS™ performance in use with Isoflurane, Sevoflurane and…
- Trial name
- OLIVER (NCT04602546)
- Testing
- BIS Complete Monitoring System
- Where
- 3 sites in United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
ColoRectal Cancer, Liver Metastasis Colon Cancer
COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation
The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.
- Conditions
- ColoRectal Cancer, Liver Metastasis Colon Cancer, Liver Metastases, Surgery
- Trial name
- COLLISION (NCT03088150)
- Testing
- Thermal ablation, Surgical resection
- Where
- Netherlands
- Volunteers
- 618 people
- Sponsor
- Amsterdam UMC, location VUmc
Hypoxia
N600X Low Saturation Accuracy Validation
To compare pulse oximetry saturation measurements, during normal to low saturation, to saturation measurements made by a multi-wavelength CO-oximeter, taken from arterial blood samples from healthy human subjects.
- Trial name
- NCT05532670
- Testing
- Non-Invasive Controlled Hypoxia
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Cancer, Lung, Cancer, Metastatic to Lung
Clinical Description of a Bronchoscopic Approach to Ablate Lung Nodules Using the Emprint™ Ablation Catheter
The purpose of this investigation is to characterize the safety and performance of the Emprint™ Ablation Catheter Kit with Thermosphere™ Technology in clinical use.
- Trial name
- NAVABLATE (NCT03569111)
- Testing
- Bronchoscopic ablation catheter
- Where
- 2 sites in Hong Kong, United Kingdom
- Volunteers
- 30 people
- Sponsor
- Medtronic - MITG
Heart Diseases
Study of Microcirculation During Extracorporeal Circulation in Cardiac Surgery
The aim of the proposed study is to evaluate microcirculatory alterations in patients undergoing open heart surgery under extracorporeal circulation.
- Trial name
- NCT04058860
- Testing
- NIRS monitoring, Cox monitoring, Sublingual microscopy
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- AHEPA University Hospital
Anesthesia
Bispectral Index and Levels of Sedation With Propofol With/Without Remifentanil in Healthy Volunteers (SONORA)
The purpose of this study is investigate the relationship between BIS™ and propofol with/without remifentanil across a wide range of hypnotic states.
- Trial name
- SONORA (NCT04466384)
- Testing
- BIS
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Obstructive Sleep Apnea, Bariatric Surgery Candidate
Capnography in the Post-Anesthesia Care Unit (PACU)
To understand if a progressive increase in end-tidal carbon dioxide (CO2) levels are heralding respiratory difficulties before desaturation measured from capnography in obstructive sleep apnea patients, with the use of nasal…
- Conditions
- Obstructive Sleep Apnea, Bariatric Surgery Candidate, Respiratory Insufficiency
- Trial name
- NCT03076047
- Testing
- end-tidal CO2 (ETCO2) monitoring
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of South Florida
Surgical Procedures, Operative
Evaluation of Efficacy and Accuracy of a Cordless Ultrasonic Dissection System
The purpose of this study is to test the efficacy of a new cordless ultrasonic dissection system.
- Trial name
- SCUD (NCT01929928)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Wake Forest University Health Sciences
Stroke
A RCT to Establish the Effectiveness of Intermittent Pneumatic Compression to Prevent Post Stroke DVT
Strokes occur when blood flow to part of the brain is interrupted. Patients are often bedbound for several days or weeks although if they survive, most will make some recovery.
- Trial name
- CLOTS-3 (NCT00789542)
- Testing
- Intermittent Pneumatic compression, Routine care
- Where
- United Kingdom
- Volunteers
- 2,876 people
- Sponsor
- University of Edinburgh
Hypoxia, Desaturation of Blood
SpO2 Accuracy Low Saturation Validation of the OxySoftN Sensor
To compare prototype pulse oximeter saturation measurements, during normal to low saturation, to saturation measurements made by a multi-wavelength CO-oximeter, taken from arterial blood samples from healthy human subjects.
- Trial name
- NCT04811963
- Testing
- Non-Invasive Controlled Hypoxia
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Lung Lesion(s) Requiring Evaluation
NAVIGATE: Clinical Evaluation of superDimension™ Navigation System for Electromagnetic Navigation Bronchoscopy™
The purpose of this study is to evaluate outcomes following electromagnetic navigation bronchoscopy™ (ENB™) procedures using the superDimension™ navigation system.
- Trial name
- NCT02410837
- Testing
- Electromagnetic Navigation Bronchoscopy
- Where
- 37 sites in United States, Austria and 5 more
- Volunteers
- 1,388 people
- Sponsor
- Medtronic - MITG
IBD
Capsule Endoscopy in Inflammatory Bowel Disease (IBD) in Children
Most of the studies evaluating the roles of MRE and WCE conducted in pediatric patients have been retrospective with the main goal of making a diagnosis in patients with suspected IBD.
- Trial name
- CE (NCT02182947)
- Testing
- Capsule endoscopy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Children's Mercy Hospital Kansas City
Respiratory Complication
LIFEGUARD Study - Continuous Respiratory Monitoring on the General Ward
The purpose of this study is to document how often and how severe are the breathing difficulties that patients suffer, while recovering on a general ward following a serious operation
- Trial name
- NCT03571646
- Testing
- Capnostream 20 monitoring, PM1000N-RR monitoring
- Where
- 2 sites in Germany
- Volunteers
- 6 people
- Sponsor
- Medtronic - MITG
Respiratory Complications
Risk Factors for Post-Operative Respiratory Complications in Patients at Risk for OSA
This study investigates the incidence of postoperative respiratory complications (PRCs) including: oxygen desaturation events, tracheal re-intubations within 48 hours of surgery, and failure to wean from ventilator within 48…
- Trial name
- NCT02729077
- Testing
- Pulse Oximetry
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Capnography
A Comparison of Capnography Sampling Lines
This study evaluates the performance of eight (8) cleared capnography carbon dioxide (CO2) sampling filterlines during patient simulated scripted activities when connected to a Medtronic (MDT) dual parameter monitor.
- Trial name
- FRS (NCT03554629)
- Testing
- Capnography CO2 cannula sampling Flexiterline (CCSF) designs with supplemental O2
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Hernia
Feasibility of Permacol Use in Infected Fields
This pilot study is to examine the feasibility of using Permacol Surgical Implant in the repair of abdominal wall defects after removal of infected prosthetic mesh
- Trial name
- NCT00820040
- Testing
- acellular porcine dermal collagen mesh
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Medtronic - MITG
Coronary Artery Disease
Multicenter Myocardial Viability Trial
The purpose of this study is to test the hypothesis of whether contrast enhanced Magnetic Resonance Imaging can be used to predict improvement of the wall motion in regions of the heart with abnormal movement following bypass…
- Trial name
- NCT00661232
- Where
- 7 sites in United States, Belgium and 4 more
- Volunteers
- 235 people
- Sponsor
- CHI St. Luke's Health, Texas
Small Bowel Disease, Inflammatory Bowel Disease
Evaluation of PillCam® Express Capsule Endoscopy Delivery System
The purpose of this study is to evaluate the safety and efficacy of a trans-endoscopic capsule placement Capsule Endoscopy Delivery System.
- Trial name
- RD-300 (NCT01088646)
- Testing
- PillCam® Express Capsule Endoscopy Delivery System
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medtronic - MITG