Clinical trials: sponsored by Shengjing Hospital
Pulmonary Embolism and Thrombosis, Deterioration, Clinical
Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary Angiography
The investigators aim to build a predictive tool for Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary Angiography.
- Conditions
- Pulmonary Embolism and Thrombosis, Deterioration, Clinical, Artificial Intelligence
- Trial name
- PEAICTPA (NCT05482269)
- Testing
- no intervention
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shengjing Hospital
Pulmonary Embolism and Thrombosis, Deterioration, Clinical
An Observational Study About Adverse Outcomes in Acute Pulmonary Embolism Patients
This multi-center retrospective study collected clinical, laboratory, and CT pulmonary angiography parameters with acute pulmonary embolism patients from admission to predict adverse outcomes within 30 days after admission into…
- Trial name
- NCT05481242
- Testing
- retrospective observational study
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shengjing Hospital
Pulmonary Embolism and Thrombosis, Deterioration, Clinical
A Predictive Tool for Predicting Adverse Outcomes in Acute Pulmonary Embolism Patients Using CTPA.
This study collected clinical, laboratory, and CT parameters of acute patients with acute pulmonary embolism from admission to predict adverse outcomes within 30 days after admission into hospital.
- Trial name
- NCT05098769
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shengjing Hospital
Postoperative Seroma Rate, Drainage Tube Removal Time, and Capsular Contracture Rate, Seroma Following Procedure
Pseudomonas Aeruginosa Injection Combined With Polyvinylpyrrolidone-Iodine in Immediate Breast Reconstruction Surgery With Implants
Brief Summary This study hypothesizes that in immediate breast reconstruction following tumor resection, the application of inactivated Pseudomonas aeruginosa preparation (PAP) may reduce infection rates by decreasing…
- Trial name
- RCT of PAI + P (NCT07460297)
- Testing
- Pseudomonas aeruginosa, Povidone-Iodine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jianyi Li
Pancreatic Cancer, Diagnose Disease
AI-Powered Precision Decision-Making for Pancreatic Diseases
This multicenter clinical trial evaluates an artificial intelligence (AI) system designed to assist in the diagnosis and management of pancreatic diseases.
- Conditions
- Pancreatic Cancer, Diagnose Disease, IPMN, Pancreatic, Pancreatic Cystic Lesions
- Trial name
- NCT07439757
- Testing
- Diagnosis by Artificial Intelligence model
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Chronic Hepatitis B, Liver Fibrosis
MR Elastography for Assessing Liver Fibrosis in Chronic Hepatitis B
How to construct a non-invasive, accurate, and convenient method to evaluate the severity of liver fibrosis (LF) is an important general problem in the management of patients with chronic hepatitis B (CHB).
- Trial name
- NCT06779058
- Testing
- MRE, Liver biopsy
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shengjing Hospital
Pancreatic Neoplasm, Magnetic Resonance Imaging
MRE for Diagnosis of Pancreatic Masses
Pancreatic ductal adenocarcinoma (PDAC) accounts for 85-95% of pancreatic cancer and is one of the deadliest tumors in the world, with a survival rate of less than 8%, and identifying key prognostic or predictive factors…
- Trial name
- MREDPCM (NCT06526442)
- Testing
- magnetic resonance imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yu Shi
Meningioma
3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features
This prospective single-center study aims to evaluate the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in assessing tumor stiffness and adhesion in patients with meningioma…
- Trial name
- NCT06955208
- Testing
- Magnetic Resonance Elastography, Intraoperative Assessment and Recording
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Spinal Cord Tumors
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment
In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue.
- Trial name
- NCT05957679
- Testing
- Magnetic Resonance Elastography, Assessment and Recording
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Chronic Kidney Disease (CKD)
Multifrequency MRE in Evaluation of Chronic Kidney Diseases
Chronic Kidney Disease (CKD) is a major public health issue, leading to high mortality and the necessity for renal replacement therapy.
- Trial name
- NCT06202235
- Testing
- Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Cirrhosis, Liver Portal Hypertension
3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension
How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis.
- Trial name
- NCT06205992
- Testing
- 3D-MRE, HVPG, 2D-MRE
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Cirrhosis, Liver, Portal Hypertension
3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension
How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis or…
- Conditions
- Cirrhosis, Liver, Portal Hypertension, Advanced Chronic Liver Disease
- Trial name
- NCT05475015
- Testing
- 3D-MRE, HVPG
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shengjing Hospital
Multiple Myeloma
Isa-VRD in TIE HRMM
This is a multicenter, prospective, randomized controlled trial designed to compare the quadruplet regimen of isatuximab, bortezomib, lenalidomide, and dexamethasone (Isa-VRD) with the standard triplet regimen (VRD) in newly…
- Trial name
- NCT07334535
- Testing
- Isatuximab, bortezomib, lenalidomide, dexamethason, Bortezomib, Lenalidomide, Dexamethasone
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Peking Union Medical College Hospital
Gout, Obesity
Orlistat and Weight Management for Uric Acid Control in Obese Gout: A RCT
A total of 120 obese gout patients were included in a 24-week double-blind randomized controlled design. The intervention group received orlistat 120 mg tid + UTL + individualized diet-exercise-behavioral reinforcement weight…
- Trial name
- OWMUAC (NCT07326839)
- Testing
- Orlistat 120 mg, Allopurinol 100 up to 600mg/day, Febuxostat 40mg Tab
- Where
- China
- Volunteers
- 120 people
- Sponsor
- XueMei Guo
Meningitis
Neuroendoscopic Surgery With Ommaya Reservoir Implantation vs. Burr Hole Drainage for Infantile Postmeningitis Subdural Lesions: Superior Efficacy, Critical Impact of Surgical Timing, and Pathogenic Bacteria as Risk Factors for Progression
Globally, approximately 750,000 cases of infantile meningitis occur annually[1]. Clinical data show infantile postmeningitis subdural fluid collection (IPSFC) is the most common complication of infantile bacterial meningitis…
- Trial name
- NCT07320599
- Testing
- Endoscopic Subdural Fluid Collection Evacuation & Ommaya Reservoir Implantation
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Hypertension
China Rural Hypertension Control Project
China Rural Hypertension Control (CRHC) Project is a cluster randomized trial that will test the effectiveness of a village doctor-led multifaceted intensive blood pressure intervention on hypertension control in 18 months (Phase…
- Trial name
- CRHC (NCT03527719)
- Testing
- Village-doctor-led multifaceted intervention
- Where
- China
- Volunteers
- 33,995 people
- Sponsor
- First Hospital of China Medical University
Infertility, Chromosome Abnormality
Embryo Selection by Noninvasive Preimplantation Genetic Test
The objective of this study is to explore whether non-invasive chromosome screening (NICS) can be used as an effective indicator for embryos selection besides morphology through a multicenter randomized controlled trial, by…
- Trial name
- ESNi-PGT (NCT04339166)
- Testing
- Non-invasive chromosome screening（NICS）
- Where
- 13 sites in China
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Cirrhosis, Decompensation
The Impact of Transjugular Intrahepatic Portosystemic Shunt on Recompensation in Patients With Decompensated Liver Cirrhosis
The traditional view holds that the natural course of cirrhosis is a unidirectional process, characterized by irreversible progression from the compensated stage to the decompensated stage, and is highly likely to develop further…
- Conditions
- Cirrhosis, Decompensation, Transjugular Intrahepatic Portosystemic Shunt (TIPS), Survival Analysis
- Trial name
- NCT07172035
- Where
- 15 sites in China
- Volunteers
- 250 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Glioma
Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion
this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we…
- Trial name
- NCT05990244
- Testing
- Magnetic Resonance Elastography, Assessment and Recording
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Interventional AI-Human Collaboration for Liver Tumor Diagnosis
Recent advances in artificial intelligence (AI), particularly deep learning technology, have transformed medical imaging analysis.
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07153783
- Testing
- AI-human collaboration for CE-CTs diagnosis
- Where
- China
- Volunteers
- 10,333 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital