Clinical trials: sponsored by University Hospital, Caen
Cancer of Kidney
Identification of Risk Factors Associated With Neoplastic Complications After Renal Transplantation in Nord-Pas de Calais , Normandy and Picardy Regions
Kidney transplantation is now the treatment of choice for end-stage renal disease (ESRD). Between 2800 and 3000 kidney transplants are performed each year in France and more than 33 000 patients are living with a functioning…
- Trial name
- FRISC (NCT02121730)
- Where
- 4 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Psychogenic Paralysis
rTMS and Functional Paralysis
Psychogenic paralysis presents a real treatment challenge. Despite psychotherapy, physiotherapy, antidepressants, acupuncture or hypnosis, the outcome is not always satisfactory with persistent symptoms after long-term follow-up.
- Trial name
- PARALYSTIM (NCT01352910)
- Testing
- rTMS
- Where
- 2 sites in France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Rouen
End Stage Chronic Renal Failure
Study of Patient Preferences in Dialysis Treatment Choice: a Discrete Choice Experiment
Background Compared to in-center dialysis, home dialysis is associated with better quality of life and lower healthcare system costs. However, barriers remain to its wider adoption.
- Trial name
- PREFDOM (NCT07535320)
- Testing
- Questionnaire
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
Antibiotics, Subcutaneous Injection
Subcutaneous Daptomycin in Healthy Volunteers (DAPTOSC)
Background: Multidrug-resistant bacteria are a major public health problem worldwide, notably due to excess mortality and an increase in the length of hospital stay.
- Conditions
- Antibiotics, Subcutaneous Injection, Daptomycin
- Trial name
- DAPTOSC (NCT04434300)
- Testing
- Daptomycin
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Cerebrovascular Disorders, Brain Lesion
Neuropsychological and Brain Medical Imaging Study in Patients With Brain Damage 2
Two groups of subjects will be constitute: (i) patients with circumscribed brain injury (including stroke, vascular malformations, tumor or circumscribed infectious lesions) or degenerative/developmental disorders and selective…
- Conditions
- Cerebrovascular Disorders, Brain Lesion, Degenerative Disease, Developmental Disability
- Trial name
- CORAC2 (NCT03586258)
- Testing
- Neuropsychological testing, Brain Imaging, Galvanic Vestibular Stimulation (GVS)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Surgery
Impact of the "Standing Patient" Pathway on Preoperative Anxiety.
For 25 years, the concept of Rapid Rehabilitation After Surgery or RRAC has developed to bring about a global care of the patient by establishing a safe and quality climate.
- Trial name
- ANXIPADE (NCT03355404)
- Testing
- standing patient
- Where
- France
- Volunteers
- 1,217 people
- Sponsor
- University Hospital, Caen
Carpal Tunnel Syndrome
Percutaneous Treatment of Carpal Tunnel Syndrome With Scan
The objective of the study is to evaluate in patients suffering from carpal tunnel syndrome resistant to medical treatment, clinical course after percutaneous treatment under ultrasound guidance.
- Trial name
- ECHOCARPE (NCT02514317)
- Testing
- percutaneous treatment, Ultrasound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Caen
Alzheimer's Disease
Multi-modal Neuroimaging in Alzheimer's Disease IMAP+
Alzheimer's disease (AD) is a major public health problem due to its socio-economic weight. An early diagnosis of AD is urgently needed as it would constitute a determinant breakthrough from a social, financial and research…
- Trial name
- IMAP+ (NCT01638949)
- Testing
- Memory assessment, Circulating biomarkers measure, ApoE4
- Where
- 7 sites in France
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Physiological Stress, Cognitive Dysfunction
DEEPTIME: Human Adaptation in Time Underground Isolation
The objectives of this scientific expedition are: a/ Evaluation of temporal cognitive perception and collective synchronization in a temporally anomalous universe (underground environment), b/ Influence of group living on the…
- Conditions
- Physiological Stress, Cognitive Dysfunction, Sleep
- Trial name
- DEEPTIME (NCT05603780)
- Testing
- exploratory protocol
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Depression, Schizophrenia
Repetitive Transcranial Magnetic Stimulation (rTMS) and P50 Evoked Potential Component
The repetitive transcranial magnetic stimulation (rTMS) is a recent technique that has demonstrated its efficiency in both depression and schizophrenia.
- Trial name
- rTMS-P50 (NCT01466439)
- Testing
- high-frequency of repetitive transcranial magnetic stimulation (rTMS), low frequency of repetitive transcranial magnetic stimulation (rTMS)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Vigilance and Simulated Driving After a Nap
The objective of this study is to assess the effectiveness of naps under different environmental conditions and a rest without nap, on driving, alertness and psychomotor performance.
- Trial name
- SOMBOX (NCT03978026)
- Testing
- Nap
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Squamous Cell Carcinoma of the Head and Neck
Nutrition and Life QUality Patients With Head and Neck Cancers
Malnutrition is currently a major factor of morbidity and mortality, which poses a major public health problem in developing countries but also, albeit to a lesser degree and for different reasons, for industrialized countries.
- Trial name
- NUQUE2 (NCT02510859)
- Testing
- Systematic nutritional consultation at home
- Where
- France
- Volunteers
- 117 people
- Sponsor
- University Hospital, Caen
Chronic Lymphocytic Leukemia
Autologous Stem Cell Transplantation in Chronic Lymphocytic Leukemia
Phase III trial evaluating the role of autologous stem cell transplantation in previously untreated patients under 65 years with stage B and C B-cell chronic lymphocytic leukemia.
- Trial name
- Auto-LLC 2001 (NCT00931645)
- Testing
- Autologous stem cell transplantation, DHAP rescue and Autologous stem cell transplantation, DHAP rescue and F+C
- Where
- France
- Volunteers
- 241 people
- Sponsor
- University Hospital, Caen
Giant Cell Arteritis
Giant Cell Arteritis and Anakinra Trial
SYNOPSIS The giant cell arteritis (GCA) is the most frequent vasculitis in people over 50 years. Despite recent progress and physiopathogenic, corticosteroids remains the standard treatment for decades with a very good initial…
- Trial name
- GiAnT (NCT02902731)
- Testing
- ANAKINRA
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Coronary Surgery With Cardiopulmonary Bypass
Effects of a Goal-directed Hemodynamic Therapy Driven by ECOM on Morbidity and Mortality After Cardiac Surgery?
Goal-directed hemodynamic and fluid optimizations are shown to be a key factor of the medical care during anesthesia.According to medical literature, goal-directed fluid and hemodynamic optimizations are more efficient when based…
- Trial name
- ECOMIII (NCT01535716)
- Testing
- hemodynamic optimization strategy driven by the ECOM, standard management strategy
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Healthy Volunteers
Study Evaluating the Relevance and Reliability of Gastrointestinal Temperature Measurements From a New Device (E-celsius)
E-Celsius device used for measuring the gastrointestinal temperature is composed of an ingestible capsule measuring the temperature as well as a transportable module receiving data from the capsule.
- Trial name
- e-TEMP (NCT02910479)
- Testing
- E-Celsius thermometer, Rectal thermometer, Esophageal thermometer
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Stress Disorders, Post-Traumatic
Stress and Emotional Memory
A broad group of disorders is associated with severe stress existence in children or adolescents. The most characteristic result, and one of the most serious being the state of post-traumatic stress disorder (PTSD), whose main…
- Trial name
- SEME (NCT02510755)
- Testing
- MRI
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Wart, Energy Medecine
Biofields Therapy on Warts
Traditionally, healers are willing to look after, two out of three French citizens have already appealed to them at least once during their lives.
- Conditions
- Wart, Energy Medecine, Magnetism
- Trial name
- MAGNETIK (NCT02773719)
- Testing
- True Biofield therapy, Fake Biofield therapy
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Caen
Untreated B-Chronic Lymphocytic Leukemia or Diffuse Large B Cells Lymphoma Patients
Dosimetry and Biodistribution of [18F]-Fludarabine in Lymphoid Malignancies
The application of positron emission tomography with lymphoproliferative diseases today provides diagnostic and therapeutic information of major importance , especially in terms of speed and quality of response to treatment.
- Trial name
- FLUDATEP (NCT02128945)
- Testing
- [18F] - Fludarabine PET/CT
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Caen
Anesthesia, Atelectasis
Comparison of Two FiO2 (1 or 0.5) for Tracheal Extubation in Post-anesthesia Care Unit
The purpose of the study is to assess the optimal fraction of inspired oxygen (0.5 or 1) for extubation or removal of a supraglottic airway device after general anesthesia.
- Conditions
- Anesthesia, Atelectasis, Postoperative Complications, Hypoxemia
- Trial name
- EXTUBO2 (NCT04879290)
- Testing
- FiO2 0.5, FiO2 1
- Where
- France
- Volunteers
- 119 people
- Sponsor
- University Hospital, Caen