Clinical trials: sponsored by Emory University
Trachoma
Trachoma Elimination Study by Focused Antibiotic (TESFA)
The study population consists of all households residing in eligible kebeles (sub-districts) within districts in Amhara National Regional State which are identified as having a high prevalence of trachoma and infection measured…
- Trial name
- NCT03523156
- Testing
- Azithromycin mass treatment, Azithromycin targeted treatment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Depression
A Study of Infliximab for Treatment Resistant Major Depression
Major depression is increasingly recognized to be a chronic and highly recurrent condition, which results in significantly increased health problems.
- Trial name
- Infliximab (NCT00463580)
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Emory University
Adherence, Medication, Risk Behavior
DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men
The researchers are working with a technology company, AiCure, to develop a smartphone app, DOT Diary, which combines two drug adherence strategies.
- Conditions
- Adherence, Medication, Risk Behavior, Pre-Exposure Prophylaxis, HIV Prevention
- Trial name
- NCT03771638
- Testing
- Emtricitabine / Tenofovir Disoproxil Oral Tablet, DOT Diary mobile app
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
Sickle Cell Disease
Building Adaptive Coping and Knowledge to Improve Daily Life
The purpose of this study is to find out how teenagers with chronic pain and sickle cell disease respond to a new training program called Back2Life and get their feedback about how to modify the program to best fit their needs.
- Trial name
- Back2Life (NCT04602728)
- Testing
- Back2Life
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Emory University
Psychological Distress, Cardiometabolic Syndrome
Shift-and-persist and Cardiometabolic Markers Among Women in Puerto Rico
The goal of this clinical trial is to evaluate the feasibility and acceptability of a 4-week mindfulness program among young women in Puerto Rico with elevated stress.
- Trial name
- NCT06250738
- Testing
- Mindfulness-based Stress reduction program: Virtual, Home exercises
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emory University
Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Ixazomib and Dexamethasone Versus Ixazomib, Dexamethasone and Lenalidomide, Randomized With NFKB2 Rearrangement
This randomized phase II trial studies how well ixazomib and dexamethasone or ixazomib, dexamethasone, and lenalidomide work based on the presence of the rearrangement of a gene called nuclear factor of kappa light polypeptide…
- Trial name
- NCT02765854
- Testing
- Dexamethasone, Ixazomib, Lenalidomide
- Where
- 4 sites in United States
- Volunteers
- 70 people
- Sponsor
- Emory University
Hysteroscopy
Green Hysteroscopy
The purpose of this study is to determine whether green draping in the operating room prior to a hysteroscopy results in a decreased operating room time.
- Trial name
- NCT06379841
- Testing
- Green Draping Procedure, Full Draping Procedure
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Prevention
Feminizing Hormone Therapy and the Rectal Mucosa Immune Environment in Transgender Women
The overarching goal of this research study is to achieve a better understanding of the rectal mucosal effects of feminizing hormones in people assigned male sex at birth and currently taking feminizing hormones who have sex with…
- Trial name
- NCT04531943
- Testing
- Estrogen, Estrogen plus Progesterone
- Where
- United States
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Emory University
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Mobile Health to Improve Oral Chemotherapy Adherence Among Women With Breast Cancer
This clinical trial evaluates the feasibility and acceptability of a mobile health device in improving oral chemotherapy adherence in women with triple negative breast cancer that has not spread to other places in the body…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT05086731
- Testing
- Best Practice, Informational Intervention, Medical Device Usage and Evaluation
- Where
- 4 sites in United States
- Volunteers
- 33 people
- Sponsor
- Emory University
Rapid Sequence Intubation
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers.
- Trial name
- NCT03840486
- Testing
- Non-rebreather mask (NRBM), Non-invasive ventilator mask (NIV), Nasal cannula EtO2 sensor
- Where
- 2 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Emory University
Asthma
Mechanisms of Interferon Gamma-primed Mesenchymal Stromal Cells (MSCs) for Moderate-to-severe Persistent Asthma
This study is a two strata, dose escalation Phase I clinical trial designed to assess the safety and determine the maximal tolerated dose (MTD) of allogenic cord tissue derived MSCs (cMSCs, stratum 1) and allogeneic, interferon-γ…
- Trial name
- NCT05035862
- Testing
- Albuterol Sulfate, Interferon gamma-primed mesenchymal stromal cells (MSCs), Prednisone
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Emory University
Extracorporeal Membrane Oxygenation Complication, Hemorrhage
ECMO Hemostatic Transfusions in Children
Critically ill children supported by extracorporeal membrane oxygenation (ECMO) receive large volumes of prophylactic platelet transfusions to prevent bleeding.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Hemorrhage, Thromboembolism, Transfusion Adverse Reaction
- Trial name
- ECSTATIC (NCT05796557)
- Testing
- Platelet Transfusion
- Where
- 10 sites in United States, Israel
- Volunteers
- 50 people
- Sponsor
- Yale University
Human Immunodeficiency Virus
Pharmacy-based Pre-exposure Prophylaxis
The proposed research will develop a culturally appropriate pharmacy pre-exposure prophylaxis (PrEP) delivery model for black men who have sex with men (BMSM) who live in high poverty, racial minority neighborhoods.
- Trial name
- NCT04393935
- Testing
- Pharmacy Delivered PrEP Intervention
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Emory University
Surgery, Anesthesia
The Pediatric Anesthesia Quality Improvement Project
The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics.
- Conditions
- Surgery, Anesthesia, Children
- Trial name
- WUS (NCT00674388)
- Where
- 37 sites in United States
- Volunteers
- 5,000,000 people
- Sponsor
- The Society for Pediatric Anesthesia
Chronic Low-back Pain
Digital Care Program for Chronic Low Back Pain
New ways of delivering care are much needed to address chronic low back pain. Crucially, these need to: a) address the three pillars of care to achieve good and sustained clinical outcomes; b) overcome barriers to access; c)…
- Trial name
- NCT04808141
- Testing
- Digital program, Conventional physical therapy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Sword Health, SA
Cancer, Pediatric Cancer
Education Tools to Support Pediatric Survivor Care
This study aims to evaluate the impact of electronic educational materials on adolescent and young adult (AYA) survivors' knowledge about late effects, perceived benefits, self-efficacy, and intentions to engage in lifelong…
- Trial name
- NCT04257058
- Testing
- Electronic educational material
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Emory University
Hyperparathyroidism
F-18 PSMA for Localization of Parathyroid Adenoma
Parathyroid glands are in the neck and produce a substance called parathormone which maintains the calcium level in the blood. Sometimes one or more of the parathyroid glands become hyperactive and produce too much parathormone…
- Trial name
- NCT05299632
- Testing
- 99mTc-MIBI planar imaging and SPECT/CT., F- 18PSMA PET/CT imaging study
- Where
- 3 sites in United States
- Volunteers
- 3 people
- Sponsor
- Emory University
Allergic Fungal Rhinosinusitis
Add-on Dupilumab for AFRS as Postoperative Therapy (ADAPT)
The purpose of this study is to find a more effective treatment for allergic fungal rhinosinusitis (AFRS). Most people suffering from nasal polyps have elevated levels of white blood cells called eosinophils that are involved in…
- Trial name
- ADAPT (NCT05545072)
- Testing
- Dupilumab, Intranasal Corticosteroid Sprays (INCS)
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Emory University
Pelvic Organ Prolapse, Prolapse, Urogenital
Race, Ethnicity, Socioeconomic Status and Prolapse-rElated Decisional ConflicT
This study is trying to see if people from different backgrounds have different feelings when making treatment decisions about prolapse.
- Trial name
- RESPECT (NCT04977141)
- Testing
- Decisional Conflict Scale
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Plasma Cell Myeloma
Carfilzomib, Pomalidomide, and Dexamethasone in Treating Patients With High-Risk Multiple Myeloma
This phase II trial studies how well carfilzomib, pomalidomide, and dexamethasone work in treating patients with high-risk multiple myeloma.
- Trial name
- NCT03756896
- Testing
- Carfilzomib, Dexamethasone, Pomalidomide
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Emory University
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