Clinical trials: sponsored by Brown University
Meningitis, Neoplasms
Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine
Subject's are being asked to take part in this study because he or she has a type of cancer that has spread to the meninges (tissues that cover the brain and spinal cord).
- Trial name
- NCT00074607
- Testing
- Gemcitabine
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Obsessive-compulsive Disorder
Radiosurgical Treatment for Obsessive-compulsive Disorder
Up to 40% of Obsessive-Compulsive Disorder (OCD) patients do not respond to conventional treatments (medications or behavior therapy). For some of them, a neurosurgical treatment can be indicated.
- Trial name
- NCT01004302
- Testing
- ventral capsular/ventral striatal gamma capsulotomy
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- University of Sao Paulo General Hospital
Adolescent Substance Use
Substance Use Prevention in Teen Psychiatric Patients
The earlier a child initiates alcohol and other drug (AOD) use, the greater the risk of long-range problems. This association persists despite changes in national substance use rates over time, indicating its stability and…
- Trial name
- tCheckup (NCT01170013)
- Testing
- Family Check-up, Parent psychoeducation
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Brown University
Alcohol Abuse
Brief Intervention for Families of Teens Treated in the Emergency Department for an Alcohol-Related Event
The purpose of this study is to compare the effectiveness of a brief family intervention in reducing alcohol use and alcohol-related problems among families of underage drinkers (13-17 years old) who are treated in a hospital…
- Trial name
- NCT00247221
- Testing
- MI/Family Check-up, MI only
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Brown University
Tobacco Use Disorder, Schizophrenia
Smoking Abstinence and Lapse Effects in Smokers With Schizophrenia and Controls
This project tests two hypotheses concerning the low smoking cessation rates in smokers with schizophrenia. The first hypothesis is that smokers with schizophrenia experience stronger and more sustained effects of smoking…
- Trial name
- WREN (NCT01214005)
- Testing
- smoking abstinence
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brown University
Asthma, Smoking Cessation
Sustaining Smoking Cessation in Smokers With Kids With Asthma
Parents of Asthmatics Quit Smoking (PAQS-2) is a randomized controlled trial of a smoking cessation intervention for parents who smoke.
- Trial name
- PAQS2 (NCT00862368)
- Testing
- PAM, PAM-Enhanced/Asthma Counseling Phone Calls, Follow-Up Phone Calls - Child Wellness Topic
- Where
- 5 sites in United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Cancer
Web-based Physical Activity Intervention for Young Adult Cancer Survivors
The goal of this study is to adapt a previously developed web-based physical activity intervention so that the intervention targets young adult cancer survivors(age 18 to 39).
- Trial name
- NCT00791375
- Testing
- Physical activity intervention
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The Miriam Hospital
Alcoholism
Matching Genotypes and Serotonergic Medications for Alcoholism
Sertraline, a serotonin-specific reuptake inhibitor (SSRI) that increases basal serotonin levels, was shown to reduce alcohol consumption in lower risk/severity and later onset (LOA) but not higher risk/severity earlier onset…
- Trial name
- NCT01113164
- Testing
- Ondansetron and Sertraline
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Brown University
Smoking Cessation
Yoga for Smoking Cessation Feasibility Study
The purpose of this study is to test whether it is feasible to provide a smoking cessation program together with a yoga program to help women quit smoking.
- Trial name
- NCT01030068
- Testing
- Yoga, Wellness, Smoking cessation therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Binge Drinking, Alcohol Abuse
Cognitive Behavioral Treatment to Reduce Alcohol Use Among HIV-Infected Kenyans
This study will determine whether a cognitive behavioral intervention that demonstrates strong evidence in the U.S. of reducing alcohol use is effective when delivered by paraprofessionals in Kenya and compared against a usual…
- Conditions
- Binge Drinking, Alcohol Abuse, Alcohol Dependence, HIV Infections
- Trial name
- KHBS (NCT00792519)
- Testing
- HIV support group, CBT
- Where
- Kenya
- Volunteers
- 75 people
- Sponsor
- Brown University
Apathy, Alzheimer's Disease
Treatment of Apathy in Alzheimer's Disease With Modafinil
This study examined the effects of modafinil on apathetic symptomatology, performance of activities of daily living (ADLs) and caregiver burden in individuals with Alzheimer's disease (AD).
- Trial name
- NCT01172145
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Abuse, Alcohol Dependence
Enhanced Motivational Interviewing With Alcohol Positive Trauma Patients
The primary goal of this study is to test the efficacy of a brief intervention that includes the patient and a significant other, relative to an intervention including the patient only, for reducing alcohol use and…
- Trial name
- NCT00280488
- Testing
- Motivational Interview, Assessment
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Brown University
HIV Infections
Project ICARE: Intervening for Community Awareness, Respect, & Empowerment
This project will test the efficacy of a behavioral intervention to reduce sexual risk for HIV infection among African American Men who Have Sex with Men (MSM).
- Trial name
- NCT00712088
- Testing
- Project ICARE, HCT
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Adherence to CPAP in Obstructive Sleep Apnea
Evaluating Behavioral Treatments to Improve Adherence to CPAP in People With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person repeatedly stops breathing or experiences shallow breathing for short periods of time during sleep.
- Trial name
- BREATHE (NCT00939601)
- Testing
- Motivational Enhancement Therapy, Educational Counseling
- Sponsor
- Brown University
Alcohol Dependence
Research on Individualized Treatment for Alcoholism
The purpose of this study was to compare the effects of two psychosocial treatments that differed in scope and intensity (Broad Spectrum Treatment and Motivational Enhancement Treatment) combined with 3 or 6 months of treatment…
- Trial name
- RITA (NCT00523133)
- Testing
- naltrexone, Broad Spectrum Treatment, Motivational Enhancement Treatment
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Indiana University
Cardiovascular Disease
Interactive Technologies to Increase Exercise Behavior
The purpose of this study is to examine if an individually tailored Internet intervention is more efficacious than an individually tailored print-based intervention and standard Internet intervention for physical activity…
- Trial name
- NCT00200317
- Testing
- Internet and print-based interventions
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Opioid-Related Disorders, HIV Infections
Buprenorphine and Integrated HIV Care Evaluation
The purpose of this study is to assess the feasibility, cost and effectiveness of interventions designed to integrate buprenorphine treatment for opioid dependence into HIV primary care in ten HIV care centers in the U.S.
- Conditions
- Opioid-Related Disorders, HIV Infections, AIDS
- Trial name
- NCT00124358
- Testing
- Buprenorphine, Integrated HIV care and office-based opioid dependence treatment
- Where
- 10 sites in United States
- Volunteers
- 1,350 people
- Sponsor
- The New York Academy of Medicine
Morton's Neuroma
Comparison of Alcohol and Steroid Injection for Treating Morton's Neuroma
Interdigital neuroma is a painful forefoot disorder characterized by plantar pain and toe paresthesias thought to result from entrapment of the interdigital nerve by the overlying transverse metatarsal ligament.
- Trial name
- NCT00284583
- Testing
- Injection of Steroid into Foot, Injection of Alcohol into Foot, Injection of Lidocaine into Foot
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brown University
Melanoma
The Use of Mole Mapping Diagrams to Increase Skin Self Examination Accuracy
This study aims to improve Skin Self-Examination accuracy by a simple cost effective intervention requiring participants to complete a mole-mapping diagram.
- Trial name
- NCT00237965
- Testing
- Mole Mapping Diagram
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brown University
Cardiovascular Disease
Exercise Instruction Via Phone or Print
The objective of this study is to determine the differential effect of intervention delivery channel (phone versus print versus wait list control) on physical activity adoption and maintenance in previously sedentary adults.
- Trial name
- NCT00200278
- Testing
- PROJECT STRIDE
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital