Clinical trials: not yet recruiting
Multi Drug Resistant Infections, Pneumnia
Traditional Chinese Medicine in Multidrug-Resistant Bacterial Pneumonia
This is a multicenter prospective observational cohort study involving hospitalized adult patients with multidrug-resistant bacterial pneumonia.
- Trial name
- MDRBP-TCM (NCT07726095)
- Where
- China
- Volunteers
- 652 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Knee Arthroplasty, Total, Partial Knee Arthroplasty
Opioid Reduction and Enhanced Recovery in Orthopaedic Surgery (OREOS)-Knee
Knee replacements are the second most common surgery in Canada. Most patients recover very well but research consistently shows that 1 in 5 patients still have pain many months after surgery.
- Conditions
- Knee Arthroplasty, Total, Partial Knee Arthroplasty, Chronic Pain, Postoperative, Osteoarthritis (OA) of the Knee
- Trial name
- OREOS-K (NCT07895472)
- Testing
- Standard care, Multicomponent opioid reduction and pain management pathway
- Volunteers
- 170 people
- Sponsor
- McMaster University
Chronic Low Back Pain, Urinary Incontinence
Radiofrequency and Pelvic Floor-Core Exercise for Chronic Low Back Pain in Women With Pelvic Floor Dysfunction
The goal of this clinical trial is to learn whether capacitive-resistive radiofrequency, a supervised core and pelvic floor exercise programme, or both together reduce low back pain in premenopausal women with chronic…
- Conditions
- Chronic Low Back Pain, Urinary Incontinence, Pelvic Floor Disorders
- Trial name
- NCT07906431
- Testing
- Capacitive-resistive radiofrequency, Lumbopelvic-pelvic floor therapeutic exercise
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- SERGIO MONTERO NAVARRO
Malnutrition, Sarcopenia
Malnutrition and Sarcopenia in Adults With Chronic Kidney Disease in Tunisia
The TUN-CKDN study is a national, multicenter, prospective cohort study conducted in nephrology centers in Tunisia. It aims to describe how often malnutrition and sarcopenia (loss of muscle strength and muscle mass) occur in…
- Conditions
- Malnutrition, Sarcopenia, Renal Insufficiency, Chronic
- Trial name
- TUN-CKDN (NCT07906405)
- Testing
- Standardized nutritional and muscle assessment
- Where
- Tunisia
- Volunteers
- 4,000 people
- Sponsor
- Dacima Consulting
Melanoma
Combination Immunotherapy Targeting Melanoma
The purpose of this study is to assess the feasibility, safety and efficacy of combination immunotherapy based on CAR T cells, cytotoxic T lymphocytes (CTLs), and dendritic cell (DC) vaccines modified with GM-CSF and B7-2 (CD86)…
- Trial name
- NCT06739226
- Testing
- Antigen-specific CAR T, CTL and DCvac to treat melanoma.
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
Helicobacter Pylori
Pilot Study of a Gastric String Test Combined With a Rapid Antigen Assay for Helicobacter Pylori Detection
This single-center, open-label, prospective pilot study aims to evaluate the feasibility, safety, and preliminary diagnostic performance of a minimally invasive gastric string sampling device combined with a rapid antigen assay…
- Trial name
- NCT07906938
- Testing
- HP String Test With Rapid Antigen Assay
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
Respiratory Muscle Function and Football Performance
Acute Effects of Breathing Resistance During Exercise in Football Players
This randomized crossover study will examine the immediate effects of breathing resistance during exercise in 35 active football players aged 18-30 years.
- Trial name
- NCT07907510
- Testing
- Breathing-Resistance Exercise Mask, No-Mask Exercise
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Graft Healing
Full-Thickness Skin Graft Sizing and Scar Quality
This study will compare three different full-thickness skin graft sizes (90%, 100%, and 110% of the surgical defect size) in patients undergoing reconstruction of nasal or ear surgical defects.
- Trial name
- NCT07896317
- Testing
- Full-Thickness Skin Graft Sizing
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alcohol, Cannabis
A Hybrid Type 1 Randomized Controlled Trial of an Online and Text-Messaging Intervention to Prevent Alcohol and Cannabis Initiation, Escalation, and Consequences Among First-Year College Students
Building on promising pilot findings, this study will employ a Hybrid Type 1 Effectiveness-Implementation RCT to evaluate the effectiveness of a novel intervention for first-year college students who abstain from or use alcohol…
- Trial name
- NCT07905846
- Testing
- Online and Text Message Intervention
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Hypertension (HTN), Hypertension
A Study to Evaluate the Effectiveness and Safety of S-amlodipine-based Monotherapy and Combination Therapy
This study aims to evaluate the effectiveness, safety, and clinical utility as a treatment strategy of the s-amlodipine-based monotherapy, dual combination, and triple combination in patients with hypertension across various…
- Conditions
- Hypertension (HTN), Hypertension, Essential (Primary) Hypertension
- Trial name
- STRIKE (NCT07907822)
- Volunteers
- 4,528 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Preoperative Anxiety
Effect of Animation-Assisted Preoperative Information on Anxiety in Adolescents Undergoing Elective Surgery
This study aims to find out whether adding a short educational animation to standard preoperative information can help reduce anxiety in adolescents aged 12-17 years who are scheduled for elective surgery.
- Trial name
- NCT07901231
- Testing
- Animation-Assisted Preoperative Information
- Volunteers
- 148 people
- Sponsor
- Ankara City Hospital Bilkent
Breast Cancer Surgery, Breast Cancer Surgery Pain
Impact of High Thoracic Paravertebral Block on Diaphragmatic Function: a Prospective Study
The high thoracic paravertebral block is a regional anesthesia technique commonly used for oncologic breast surgery. Local anesthetic is injected into the paravertebral space to provide anesthesia and pain relief.
- Conditions
- Breast Cancer Surgery, Breast Cancer Surgery Pain, Hemidiaphragmatic Paralysis
- Trial name
- NCT07907692
- Testing
- High thoracic paravertebral block
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Depression, Anxiety
Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology Continuum
Background: Making decisions during daily life is a complicated behavior. Even simple choices can be affected by a range of emotions, stresses, and moods.
- Conditions
- Depression, Anxiety, Addiction, Emotion
- Trial name
- NCT07801079
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- National Institute of Mental Health (NIMH)
PARKINSON DISEASE (Disorder), Older Adults (65-85 Years)
Perception of Action Opportunities for Obstacle Crossing in Parkinson's Disease
The study examines how individuals with Parkinson's disease, compared to healthy older adults, evaluate their ability to cross an obstacle, and the association between this evaluation, motor and cognitive status, and…
- Trial name
- NCT07907770
- Testing
- Obstacle Crossing Task
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Down Syndrome, Trisomy 21
Executive Function Play Opportunities for Children With Down Syndrome
The Executive Function Play Opportunities (EXPO) study is a sequential, multiple assignment, randomized trial (SMART) evaluating adaptive caregiver-mediated intervention pathways for improving executive function (EF) in children…
- Trial name
- EXPO (NCT07792382)
- Testing
- EXPO, EXPO Extended, EXPO Foundations
- Where
- 2 sites in United States, Italy
- Volunteers
- 150 people
- Sponsor
- Colorado State University
Iron Deficiency Anemia
Effect of Vitamin D Supplementation Added to Iron Therapy in Children With Iron Deficiency Anemia
This randomized controlled trial will evaluate the effect of two vitamin D3 supplementation regimens, administered in addition to oral iron therapy, on hematological and iron status in children aged 6-60 months with confirmed…
- Trial name
- NCT07892170
- Testing
- Elemental iron, Vitamin D3 2000 IU/day, Vitamin D3 400 IU/day
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- AlFayhaa General Hospital
Interdental Papilla Deficiency
Microneedling-Assisted i-PRF for Interdental Papilla Deficiency
Loss of the gum tissue between teeth can leave visible gaps called black triangles. This study will compare injectable platelet-rich fibrin (i-PRF), prepared from the participant's own blood, with i-PRF combined with…
- Trial name
- MN-iPRF (NCT07907939)
- Testing
- Autologous injectable platelet-rich fibrin (i-PRF), Microneedling of the interdental papilla
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ehab Ayman Hussien Mohamed Abdelaal
Continuous Renal Replacement Therapy (CRRT), Magnesium
Magnesium Kinetics During Citrate-Anticoagulated CRRT
The goal of this observational study is to assess how continuous renal replacement therapy (CRRT), a type of dialysis used in critically ill patients, affects magnesium levels in adults treated in intensive care units (ICUs).
- Trial name
- NCT07906340
- Testing
- Serial blood and dialysis circuit fluid sampling
- Volunteers
- 35 people
- Sponsor
- Region Skane
Endometriosis, Adenomyosis
Psychotherapy in Patients With Endometriosis: Cognitive Behavioral Therapy Versus Acceptance and Commitment Therapy
The aim of the present study is to compare two types of psychotherapeutic interventions in women with endometriosis and/or adenomyosis: cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT).
- Trial name
- T-ENDO (NCT07907848)
- Testing
- Cognitive Behavioral Therapy (CBT), Acceptance and Commitment Therapy (ACT)
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Fiammetta Cosci
Typhoid Carrier, Typhoid Fever
Curcumin Extract Added to Ciprofloxacin for Typhoid Carriers Among Food Handlers of the Free Nutritious Meal Program
Some people keep carrying Salmonella Typhi after they recover from typhoid fever. These carriers have no symptoms. They can still pass the bacteria into food.
- Conditions
- Typhoid Carrier, Typhoid Fever, Salmonella Typhi Infection
- Trial name
- NCT07908030
- Testing
- Curcumin extract, Ciprofloxacin
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitas Sebelas Maret
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