Clinical trials: sponsored by Alcon Research
Myopia
Clinical Evaluation of a Silicone Hydrogel Lens
The purpose of this study is to assess the performance of an investigational contact lens among contact lens wearers.
- Trial name
- NCT01016132
- Testing
- lotrafilcon A contact lens
- Volunteers
- 152 people
- Sponsor
- CIBA VISION
Presbyopia
Comparison of Two New Silicone Hydrogel Multifocal Products
The purpose of this trial is to compare the performance of two multifocal contact lenses.
- Trial name
- NCT00823615
- Testing
- Lotrafilcon B multifocal contact lens, Senofilcon A multifocal contact lens
- Volunteers
- 40 people
- Sponsor
- CIBA VISION
Myopia
Evaluation of Lotrafilcon A Lenses Over a Three Month Period
The purpose of this trial is to assess the performance of a Lotrafilcon A contact lens over a 3-month period.
- Trial name
- NCT00931307
- Testing
- Lotrafilcon A contact lens
- Volunteers
- 22 people
- Sponsor
- CIBA VISION
Myopia
Non-dispense Comfort Comparison of Two Silicone Hydrogel Lenses
The purpose of this study is to compare subjective responses to two contact lenses after 15 minutes of wear.
- Trial name
- NCT00808834
- Testing
- Lotrafilcon A contact lens, Senofilcon A contact lens
- Volunteers
- 196 people
- Sponsor
- CIBA VISION
Cosmetic Appearance
Asian Clinical Evaluation of an Investigational Contact Lens for Cosmetic Effect
The purpose of this study is to compare the cosmetic appearance of two different contact lenses on Asian eyes.
- Trial name
- NCT01446835
- Testing
- nelfilcon A contact lens with print, etafilcon A contact lens with print
- Where
- Singapore
- Volunteers
- 151 people
- Sponsor
- CIBA VISION
Glaucoma
Efficacy and Safety of Travoprost 0.004% Versus Tafluprost 0.0015% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension
The purpose of this study is to assess the safety and efficacy of Travoprost 0.004% and Tafluprost 0.0015% in patients with primary open angle glaucoma or ocular hypertension when both medications are administered in the evening.
- Trial name
- NCT00966940
- Testing
- Travoprost 0.004% ophthalmic solution (TRAVATAN), Tafluprost 0.0015% ophthalmic solution
- Volunteers
- 51 people
- Sponsor
- Alcon Research
Contact Lens Wear
Evaluation of Silicone Hydrogel Lens Wettability With Marketed Lens Care Solutions
The purpose of this study is to assess ex vivo wettability of a commonly prescribed silicone hydrogel (SiH) contact lens with three marketed contact lens care solutions.
- Trial name
- SILVER (NCT01252134)
- Testing
- Biotrue multipurpose solution, Sauflon Synergi multipurpose solution, OTE Elements multipurpose solution
- Volunteers
- 22 people
- Sponsor
- Alcon Research
Blepharitis
A Study to Evaluate the Clinical Efficacy and Safety of Tobradex® ST Compared to Azasite® in the Treatment of Subjects With Moderate to Severe Chronic Blepharitis
The purpose of this study is to evaluate the clinical efficacy and safety of Tobradex ST compared to AzaSite in the treatment of moderate to severe chronic blepharitis.
- Trial name
- NCT01102244
- Testing
- Tobradex ST, Azasite
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Alcon Research
Dry Eye
Phase II Study of AL-2178 (FID 109980) in the Treatment of Dry Eye
The purpose of this study is to see if Rimexolone (FID 109980) is a safe and effective treatment of dry eye.
- Trial name
- NCT00471419
- Testing
- Rimexolone
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Alcon Research
Dry Eye
Optimization of Assessment and Grading for Lid Wiper Epitheliopathy
The purpose of this study is to assess eyelid margin staining, termed "lid wiper epitheliopathy" (LWE), in three populations. The hypothesis is LWE will be more prevalent in symptomatic contact lens wearers than non-symptomatic…
- Trial name
- BURNABY (NCT01611922)
- Testing
- Ophthalmic dye, Contact lenses
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Uveitis, Posterior, Glaucoma
Prophylactic Anecortave Acetate in Patients With a Retisert Implant
Retisert implant is an effective therapy for controlling inflammation in patients with non-infectious posterior uveitis. One of the major complications of this device is the development of elevated intraocular pressure (IOP)…
- Trial name
- NCT00570479
- Testing
- anecortave acetate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Texas Retina Associates
Allergic Conjunctivitis
Efficacy Investigation Study of Olopatadine Hydrochloride Ophthalmic Solution Using OHIO Chamber in Patients With Seasonal Allergic Rhinitis (SAR)
To evaluate the efficacy of olopatadine 0.1% using the OHIO Chamber in patients with seasonal allergic conjunctivitis.
- Trial name
- NCT00818805
- Testing
- Olopatadine 0.1%, Tranilast 0.5%
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Open-angle Glaucoma, Ocular Hypertension
Examination of Ocular Surface Effects With Administration of Travatan Z and XALATAN
The purpose of this study is to compare two ophthalmic solutions in patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00798759
- Testing
- Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®), Latanoprost ophthalmic solution 0.005% (XALATAN®)
- Volunteers
- 236 people
- Sponsor
- Alcon Research
Ocular Hypertension, Primary Open Angle Glaucoma
Glaucoma Adherence Study
The purpose of this study is evaluate adherence to DuoTrav® when reinforced by the use of the Travalert™ Dosing Aid.
- Trial name
- GAS (NCT00676637)
- Testing
- Travoprost 0.004%/timolol 0.05% fixed combination eye drops (DuoTrav), Travalert Dosing Aid
- Where
- 4 sites in France, Italy and 2 more
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Ocular Hypertension, Primary Open Angle Glaucoma
Glaucoma Adherence Study, Spain
The purpose of this study is to evaluate adherence to DuoTrav® when reinforced by the use of the Travalert™ Dosing Aid.
- Trial name
- GAS (NCT00680329)
- Testing
- Travoprost 0.004%/timolol 0.05% fixed combination eye drops (DuoTrav), Travalert Dosing Aid
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Open-Angle Glaucoma
A Multi-Dose Study With a Treatment for Open-Angle Glaucoma
The purpose of this study is to determine whether Anecortave Acetate is effective for lowering intraocular pressure caused by open-angle glaucoma.
- Trial name
- NCT00705770
- Testing
- Anecortave Acetate
- Sponsor
- Alcon Research
Glaucoma
Prevalence of Ocular Surface Disease in Glaucoma Patients
Demographic information and a brief medical and concomitant medicine history will be obtained from the glaucoma patient's records. Qualified patients will be asked to complete a questionnaire about their symptoms.
- Trial name
- NCT00382122
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Alcon Research
Glaucoma
Short Term Comparative Study of Xalatan With Benzalkonium Chloride vs. Travatan Z Without Benzalkonium Chloride in Healthy Volunteers
Compare the effect of Xalatan with benzalkonium chloride on the ocular surface to those effects observed with Travatan Z without benzalkonium chloride after a single dose
- Trial name
- NCT00468988
- Testing
- Travatan® Z, Xalatan®
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Open-Angle Glaucoma, Ocular Hypertension
A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to compare the comfort of Travatan Z in one eye and Xalatan in the opposite eye in patients with primary open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00527592
- Testing
- Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®), Latanoprost ophthalmic solution 0.005% (XALATAN®)
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Open-angle Glaucoma, Ocular Hypertension
Phase III Clinical Trial of TRAVATAN Z in Ocular Surface Health
The purpose of the study is to compare two ophthalmic solutions in patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00761319
- Testing
- Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®), Latanoprost ophthalmic solution 0.005% (XALATAN®)
- Volunteers
- 705 people
- Sponsor
- Alcon Research