Clinical trials: sponsored by Emory University
ISS Stage I Plasma Cell Myeloma, ISS Stage II Plasma Cell Myeloma
Pembrolizumab and Radiation Therapy in Patients With Relapsed or Refractory Multiple Myeloma
This pilot clinical trial studies the side effects of pembrolizumab and radiation therapy in treating patients with stage I-III multiple myeloma that has come back after a period of improvement or that does not respond to…
- Conditions
- ISS Stage I Plasma Cell Myeloma, ISS Stage II Plasma Cell Myeloma, ISS Stage III Plasma Cell Myeloma, Recurrent Plasma Cell Myeloma
- Trial name
- NCT03267888
- Testing
- Pembrolizumab, Radiation Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Brain Injuries
Cortical Contributions to Motor Sequence Learning
The long-term objective initiated with this study is to determine which brain areas functionally contribute to learning a motor skill.
- Trial name
- NCT04138953
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Emory University
Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8
Sirolimus and Durvalumab for the Treatment of Stage I-IIIA Non-small Cell Lung Cancer
This trial studies the side effects of sirolimus and durvalumab and to see how well they work in treating patients with stage I-IIIA non-small cell lung cancer.
- Conditions
- Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8
- Trial name
- NCT04348292
- Testing
- Durvalumab, Sirolimus
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Emory University
Anesthesia, Local
Lidocaine Administration Using STAR Particles
This study is being done to answer the question: Do STAR particles (tiny pieces of ceramic with small spikes) help numbing gel (a gel that helps you feel less pain) work more quickly to provide local anesthesia or numbing in a…
- Trial name
- NCT06034340
- Testing
- LET Gel after STAR Particle Application (Right or Left Arm), LET Gel Application without STAR Particle Application (Contralateral Arm)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Emory University
Mycosis Fungoides, Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
Mogamulizumab and Extracorporeal Photopheresis for the Treatment of Sezary Syndrome or Mycosis Fungoides
This phase Ib/II trial investigates the side effects of mogamulizumab and extracorporeal photopheresis and to see how well they work in treating patients with Sezary syndrome or mycosis fungoides.
- Conditions
- Mycosis Fungoides, Primary Cutaneous T-Cell Non-Hodgkin Lymphoma, Sezary Syndrome
- Trial name
- NCT04676087
- Testing
- Extracorporeal Photopheresis, Mogamulizumab, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Emory University
Zoster, Zoster Varicella
Systems Biology of Zoster Vaccine
The purpose of the study is to better understand how the immune system responds to the new herpes zoster (shingles) vaccine (Shingrix®). The study will be looking at certain markers in the blood after vaccination with Shingrix®.
- Conditions
- Zoster, Zoster Varicella, Shingles, Chicken Pox
- Trial name
- NCT04047979
- Testing
- Shingrix®
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Emory University
Femur Fracture
Study Comparing Ultrasound-guided FICNB Block to Systemic Analgesia in Treatment of Pediatric Femur Fracture
The goal of this prospective observational study is to compare pain control strategies in children with femur fractures. Researchers will compare ultrasound-guided fascia iliaca compartment nerve block to IV pain control alone.
- Trial name
- PLEXUS (NCT05947292)
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Nerve Block
- Where
- 10 sites in United States, Australia
- Volunteers
- 114 people
- Sponsor
- Zachary Binder
Anterior Cruciate Ligament Injuries
Neuroplastic Mechanisms Underlying Augmented Neuromuscular Training
The purpose of this study is to determine the neural mechanisms of augmented neuromuscular training (aNMT). Participants will complete a 6-week course of neuromuscular training with either aNMT biofeedback or sham biofeedback.
- Trial name
- NCT04069520
- Testing
- aNMT Biofeedback
- Where
- 2 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Emory University
Burnout, Professional
Coaching for Advanced Practice Providers
This study aims to determine if online coaching is feasible in advanced practice providers (APP) and can impact burnout. The study will recruit APPs from Children's Healthcare of Atlanta (CHOA), Emory, Colorado University (CU)…
- Trial name
- NCT05938556
- Testing
- hybrid asynchronous-synchronous group coaching program, treatment as usual group (TAU)
- Where
- 4 sites in United States
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Emory University
HCV
Xpert Hepatitis-C Virus (HCV) Test on the GeneXpert Xpress System
A multi-site prospective, all comers study that was conducted at geographically diverse locations in the United States.
- Trial name
- NCT06508996
- Testing
- Xpert HCV
- Where
- United States
- Volunteers
- 1,012 people
- Sponsor
- Cepheid
Hemophilia A
Hematopoietic Stem Cell Transplantation Gene Therapy for Treatment of Severe Hemophilia A
Factor VIII (FVIII) is a large plasma glycoprotein that participates in blood coagulation. Loss of circulating FVIII activity due to mutations within the F8 gene results in the X-linked, recessive bleeding disorder hemophilia A.
- Trial name
- NCT05265767
- Testing
- Auto CD34+PBSC transduced with a lentiviral vector encoding a novel coagulation factor VIII transgene
- Where
- India
- Volunteers
- 6 people
- Sponsor
- Christian Medical College, Vellore, India
Stroke, Ischemic, Intracranial Atherosclerosis
Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study
Early identification of intracranial atherosclerotic disease (ICAD) may impact the management of patients undergoing mechanical thrombectomy (MT).
- Conditions
- Stroke, Ischemic, Intracranial Atherosclerosis, Posterior Circulation Brain Infarction
- Trial name
- NCT06453252
- Testing
- we are aiming to develop a Scoring system based on certain variables derived from both groups
- Where
- 2 sites in United States, Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Plasma Cell Myeloma
Pembrolizumab as Salvage Therapy for the Treatment of Multiple Myeloma in Patients Progressing on CAR-T Cell Therapy
This phase II trial studies the effect of pembrolizumab in treating patients with multiple myeloma that is growing, spreading, or getting worse (progressing) on chimeric antigen receptor (CAR)-T cell therapy.
- Trial name
- NCT05204160
- Testing
- Pembrolizumab
- Where
- United States
- Sponsor
- Emory University
Plasma Cell Myeloma, Renal Failure
Daratumumab-Based Therapy for the Treatment of Newly Diagnosed Multiple Myeloma With Kidney Failure
This phase II trial studies how well daratumumab-based therapy works in treating patients with newly diagnosed multiple myeloma with kidney failure.
- Trial name
- NCT04352205
- Testing
- Bortezomib, Daratumumab, Dexamethasone
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Emory University
COVID-19
Multisite Observational Maternal and Infant Study for COVID-19
This is an observational, non-interventional, prospective cohort study designed to collect clinical information and specimens to evaluate the immune responses from pregnant individuals and postpartum individuals and their infants…
- Trial name
- MOMI-Vax (NCT05031468)
- Testing
- Licensed or EUA SARS-CoV-2 vaccine
- Where
- 10 sites in United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Emory University
Renal Transplant
Characterization Of the Intestinal Microbiome Evolution After Kidney Transplant Donation or Receipt
This is a hypothesis-generating pilot study. The intent is to model the impact of perioperative practices on the intestinal microbiome and possibly associate these conditions with the final microbiome status (e.g., number of…
- Trial name
- COMET-DR (NCT03043339)
- Testing
- Stool Specimen Collection, Anal Swab Sampling, Short Diet Assessment (SDA)
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Emory University
Recurrent Skin Carcinoma, Skin Squamous Cell Carcinoma
Pembrolizumab in Patients With Locally Advanced or Metastatic Skin Cancer
This phase II trial studies how well pembrolizumab works in treating patients with skin cancer that has spread from where it started to nearby tissue, lymph nodes, or other parts of the body.
- Trial name
- NCT02964559
- Testing
- Pembrolizumab
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Emory University
Prostate Carcinoma
Comprehensive Yoga Program (SKY) as Adjunct Therapy for Prostate Cancer
This randomized pilot trial studies the effect of comprehensive yoga program (SKY) in reducing stress, pain, and fatigue, and improving psychological well-being in patients with prostate cancer.
- Trial name
- NCT03220945
- Testing
- Yoga
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Emory University
Plasma Cell Myeloma
Daratumumab, Ixazomib, & Dexamethasone or Daratumumab, Bortezomib, & Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma
This phase II trial studies how well daratumumab, ixazomib, and dexamethasone with or without bortezomib work in treating patients with newly diagnosed multiple myeloma.
- Trial name
- DeRIVE (NCT03942224)
- Testing
- Bortezomib, Daratumumab, Dexamethasone
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Emory University
Type 2 Diabetes
Well-child Visit Video Project
The purpose of this study is to determine if incorporating videos on the importance of minimizing infant sugar-containing beverage (SCB) consumption into well-child visit protocols increases parents' SCB-related knowledge and…
- Trial name
- NCT05011292
- Testing
- Educational Video about SCB, Survey on child feeding and related knowledge and practices, Educational Video other than SCB
- Where
- United States
- Volunteers
- 388 people
- Sponsor
- Emory University
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